Anti-allergic effects of two potential probiotic strains isolated from infant feces in China

Liang, Huijing; Zhang, Yujie; Miao, Zhonghua; Cheng, Ruyue; Jiang, Fengling; Ze, Xiaolei; Shi, Xi; He, Fang

doi:10.1016/j.jff.2022.105070

Cited by 6 publications

(3 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Liang et al evaluated the antiallergic effects of probiotics isolated from infant feces in OVA-sensitized mice and found that OVA-induced gut microbial dysbiosis was featured by a significant increase in Alloprevotella, despite their SCFA-producing ability. 50 On the other hand, Alloprevotella has been reportedly associated with the pathogenesis of ulcerative colitis in mice. 51 We speculated that such inconsistencies could be attributed to heterogeneity in animal species, microbiota analysis methods, and study design.…”

Section: Discussionmentioning

confidence: 99%

“…Alloprevotella is a member of the family Prevotellaceae, and there is some controversy concerning its role in allergic diseases. Liang et al evaluated the antiallergic effects of probiotics isolated from infant feces in OVA-sensitized mice and found that OVA-induced gut microbial dysbiosis was featured by a significant increase in Alloprevotella , despite their SCFA-producing ability . On the other hand, Alloprevotella has been reportedly associated with the pathogenesis of ulcerative colitis in mice .…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Combination of Gut Microbial Features and the Proteomic Pattern Revealed Changes in Specific Intestinal Luminal Factors and Mechanisms of Their Regulation of Gluten Allergy

Xie

Liu

et al. 2023

J. Agric. Food Chem.

View full text Add to dashboard Cite

Recent research consensus has highlighted the role of intestinal luminal factors in the association between intestinal microenvironment homeostasis and food allergy. However, the association between intestinal immune homeostasis and food allergy-related proteomic features remains elusive. In this study, we aimed to investigate the changes in gluten allergy (GA)-defined phenotypes and endotypes and intestinal microenvironment factors in BALB/c mice and linked GA to colonic proteomic signatures. Combined with increased allergy and diarrhea scores, intense antibody responses and abnormalities in T-cell cytokine production were induced in mice. GA-associated disruption of intestinal microenvironment homeostasis was underlined by the increased colonic pH, decreased intestinal antioxidant capacity, impaired intestinal barrier function, and decreased production and imbalanced proportions of short-chain fatty acids. 16S rRNA amplicon sequencing showed that the gut microbiota dysbiosis in mice was characterized by significant enrichment of six bacterial taxonomic units, including Prevotellaceae, Escherichia Shigella, Alloprevotella, Escherichia coli, Bacteroides vulgatus, and Lachnospiraceae bacterium DW59, which was correlated with immune end points. Using a label-free proteomics quantitative approach, 24 differentially expressed proteins linking GA-induced gut dysbiosis were identified, with four of them enriched in the serine endopeptidase inhibitor activity pathway. The development of GA in mice was associated with changes in specific intestinal luminal factors and may be mediated by serine protease activity-associated metabolic routes.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Combination of Gut Microbial Features and the Proteomic Pattern Revealed Changes in Specific Intestinal Luminal Factors and Mechanisms of Their Regulation of Gluten Allergy

Xie

Liu

et al. 2023

J. Agric. Food Chem.

View full text Add to dashboard Cite

show abstract

“…Furthermore, both probiotic strains reduced serum immunoglobulin G3 (IgG3) levels and induced tumor necrosis factor-alpha (TNFα), IL-6, IL-10, and IL-12. In addition, L. paracasei 207-27 remarkedly upregulated the level of cecal SCFAs in allergic mouse models (98). Another recent study reported the potential of Lacticaseibacillus paracasei MG4272, MG4577, and MG4657 and Lactobacillus gasseri MG4247 to attenuate allergic inflammation by downregulating the expression of IL-4, IL-5, IL-13, and STAT6 phosphorylation (99).…”

Section: Immune Stimulationmentioning

confidence: 98%

Probiotics, their action modality and the use of multi-omics in metamorphosis of commensal microbiota into target-based probiotics

et al. 2022

View full text Add to dashboard Cite

This review article addresses the strategic formulation of human probiotics and allows the reader to walk along the journey that metamorphoses commensal microbiota into target-based probiotics. It recapitulates what are probiotics, their history, and the main mechanisms through which probiotics exert beneficial effects on the host. It articulates how a given probiotic preparation could not be all-encompassing and how each probiotic strain has its unique repertoire of functional genes. It answers what criteria should be met to formulate probiotics intended for human use, and why certain probiotics meet ill-fate in pre-clinical and clinical trials? It communicates the reasons that taint the reputation of probiotics and cause discord between the industry, medical and scientific communities. It revisits the notion of host-adapted strains carrying niche-specific genetic modifications. Lastly, this paper emphasizes the strategic development of target-based probiotics using host-adapted microbial isolates with known molecular effectors that would serve as better candidates for bioprophylactic and biotherapeutic interventions in disease-susceptible individuals.

show abstract

Lactic acid bacteria with probiotic characteristics in fermented dairy products reduce cow milk allergy

Guo,

Wang,

Zhao

et al. 2023

Food Bioscience

View full text Add to dashboard Cite

Anti-allergic effects of two potential probiotic strains isolated from infant feces in China

Cited by 6 publications

References 46 publications

Combination of Gut Microbial Features and the Proteomic Pattern Revealed Changes in Specific Intestinal Luminal Factors and Mechanisms of Their Regulation of Gluten Allergy

Combination of Gut Microbial Features and the Proteomic Pattern Revealed Changes in Specific Intestinal Luminal Factors and Mechanisms of Their Regulation of Gluten Allergy

Probiotics, their action modality and the use of multi-omics in metamorphosis of commensal microbiota into target-based probiotics

Lactic acid bacteria with probiotic characteristics in fermented dairy products reduce cow milk allergy

Contact Info

Product

Resources

About