2018
DOI: 10.1002/star.201700319
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Anti‐Adhesion Mesh for Hernia Repair Based on Modified Bacterial Cellulose

Abstract: Polypropylene (PP) is the most widely used biomaterial for hernia repair despite its many problems related to over fibrosis. The current study is designed to evaluate and directly compare the biomechanics and antiadhesion properties of the novel, TEMPO(2,2,6,6-tetramethylpyperidine-1oxyl)-mediated modified bacterial cellulose (TBC) mesh and the clinically used PP meshes. Laser perforation generates isotropic, flat and stable structures that prevent deformation under pressure and reduce the risk of potential ba… Show more

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Cited by 16 publications
(11 citation statements)
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References 37 publications
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“…In a similar work, oxidized and laser-perforated BNC was employed in experimental surgery using a rabbit model. 40 One week after subcutaneous suture-free BNC implantation on the animal's back a positive integration of the BNC implants with the surrounding tissues was reported following our observations. Interestingly, Lai and co-workers stated a very low inflammatory response contrasting with the here presented histological analysis.…”
Section: Papersupporting
confidence: 76%
“…In a similar work, oxidized and laser-perforated BNC was employed in experimental surgery using a rabbit model. 40 One week after subcutaneous suture-free BNC implantation on the animal's back a positive integration of the BNC implants with the surrounding tissues was reported following our observations. Interestingly, Lai and co-workers stated a very low inflammatory response contrasting with the here presented histological analysis.…”
Section: Papersupporting
confidence: 76%
“…The results showed that perforated BC membranes exhibited an improved performance, explained by its effective integration in host tissue and tissue remodeling induction effect, as well as due to its suitable biomechanical properties. Lai et al . developed and evaluated a novel TEMPO‐mediated modified bacterial cellulose (TBC) mesh to act as an antiadhesion mesh for hernia repair.…”
Section: Applicationsmentioning
confidence: 99%
“…Copyright 2020 American Chemical Society. Panel D reprinted with permission from ref . Copyright 2018 John Wiley and Sons.…”
Section: Functional Meshesmentioning
confidence: 99%