Anthropometric study of the knee in patients with osteoarthritis: intraoperative measurement versus magnetic resonance imaging

Loures, Fabrício Bolpato; Carrara, Renato Janetti; Góes, Rogério Franco de Araújo; Albuquerque, Rodrigo Pires e; Barretto, João Maurício; Kinder, André; Gameiro, Vinícius Schott; Marchiori, Edson

doi:10.1590/0100-3984.2016.0007

Cited by 18 publications

(15 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Most authors have only looked at the AP and ML dimensions for the distal femur and proximal tibia [ 5 , 6 , 12 , 24 ]. The ROC of the femoral condyles and proximal tibia are not uniform and are integral in dictating normal knee motion as the curvature of the condyles is one of the main factors affecting knee kinematics.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Morphologic Features of the Distal Femur and Proximal Tibia: A Cross-Sectional Study

Chaurasia¹,

Tyagi²,

Santoshi³

et al. 2021

Cureus

View full text Add to dashboard Cite

Background The asymmetric medial and lateral condyles of the distal femur and proximal tibia have a direct influence on the biomechanics of knee joint and prostheses design. This study aimed to determine the morphologic data, that is., anteroposterior (AP) and mediolateral (ML) widths, and the radius of curvature (ROC) of the geometric arcs of the distal femur and proximal tibia. Methods One hundred and seventeen adult dry bones (57 femurs and 60 tibias) were studied. Aspect ratios (AP/ML) were calculated. The AP and ML widths were measured using digital Vernier Caliper with a measuring range of 0-150 mm, resolution of 0.01 mm, and accuracy ± 0.02 mm. The geometric arcs of femoral and tibial condyles were divided into three parts namely anterior 1/3rd, distal (femur) or middle (tibia) 1/3rd and posterior 1/3rd and were estimated in the sagittal plane for the femur and transverse plane for tibia using the ROC gauges. Results For the femur, the mean AP length for medial and lateral condyles was 55.62 mm and 57.93 mm, respectively, while the mean ML width was 73.45 mm. For the tibia, the mean AP length for medial condyle (MC) and lateral condyle (LC) was 47.74 mm and 43.46 mm, respectively. The mean aspect ratios for the distal femur and proximal tibia were 1.26 and 1.45, respectively. The mean aspect ratios for MC and LC of the femur were 0.50 and 0.52, respectively, whereas, for tibia, they were 0.61 and 0.71, respectively. The mean ROC for femoral MC - 20.77 mm, 31.42 mm, and 19.68 mm and for LC - 21.48 mm, 64.40 mm and 19.06 mm for the anterior, distal and posterior arcs, respectively. The mean ROC for tibial MC - 22.42 mm, 22.49 mm and 19.94 mm, and LC - 19.92 mm, 21.79 mm and 20.95 mm for the anterior, middle and posterior arcs, respectively. Conclusions The morphologic data accumulated in this study for both the distal femur as well as the proximal tibia would provide guidelines and help the manufacturers of joint prostheses to address the potential for compromised implant fit and re-design and make available ‘anatomic’ knee prostheses appropriate for the local population which would not only improve function but also prolong the longevity of the prostheses.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Some previous studies have used specimen resected during surgery for anthropometric measurements [ 18 , 24 ]. The specimens obtained during knee arthroplasty surgery are obviously arthritic and may not be suitable for basing implant design.…”

Section: Discussionmentioning

confidence: 99%

Morphologic Features of the Distal Femur and Proximal Tibia: A Cross-Sectional Study

Chaurasia¹,

Tyagi²,

Santoshi³

et al. 2021

Cureus

View full text Add to dashboard Cite

show abstract

“…In recent years, many studies have found that osteoarthritis patients have immune abnormalities, and abnormal secretions of cytokines might damage cartilage function and metabolism[14,15]. In addition, aggravated gradual decomposition of cartilage matrix can bring irreversible injury to the joint structure of patients, which is manifested as the corresponding clinical symptoms, thus accelerating the progress of articular cartilage injury[16,17]. IL-1β, IL-6 and TNF-α are secreted from macrophages and immune cells, which mainly come from the lining cells of the synovial membrane.…”

Section: Discussionmentioning

confidence: 99%

Elevated levels of interleukin-1β, interleukin-6, tumor necrosis factor-α and vascular endothelial growth factor in patients with knee articular cartilage injury

Wang

Chen

Hao

et al. 2019

WJCC

View full text Add to dashboard Cite

BACKGROUND Inflammatory cytokines play a vital role in the occurrence of osteoarticular injury and inflammation. Whether inflammation-associated factors interleukin-1β (IL-1β), IL-6, tumor necrosis factor-α (TNF-α) and vascular endothelial growth factor (VEGF) are involved in the pathogenesis of keen articular cartilage injury remains poorly understood. AIM To measure the levels of inflammatory factors [IL-1β, IL-6, TNF-α and VEGF] in patients with knee articular cartilage injury. METHODS Fifty-five patients with knee articular cartilage injury were selected as patient groups, who were divided into three grades [mild ( n = 20), moderate ( n = 19) and severe ( n = 16)] according to disease severity and X-ray examinations. Meanwhile, 30 healthy individuals who underwent physical examination were selected as the control group. The levels of IL-1β, IL-6, TNF-α and VEGF were measured by ELISA and immunohistochemical staining. RESULTS Compared with the control group, patient groups displayed significantly higher levels of IL-1β, IL-6, TNF-α and VEGF, and the extent of increase was directly proportional to the severity of injury ( P < 0.05). In addition, the number of cells with positive staining of IL-1β, IL-6, TNF-α and VEGF in the synovial membrane were significantly increased, along with increased disease severity ( P < 0.05). After treatment, the scores of visual analogue scale and the Western Ontario and McMaster University of Orthopaedic Index in patient groups were 2.26 ± 1.13 and 15.56 ± 7.12 points, respectively, which were significantly lower than those before treatment (6.98 ± 1.32 and 49.48 ± 8.96). Correlation analysis suggested that IL-1β and TNF-α were positively correlated with VEGF. CONCLUSION IL-1β, IL-6, TNF-α and VEGF levels are increased in patients with knee articular cartilage injury, and are associated with the disease severity, indicating they might play an important role in the occurrence and development of knee articular cartilage injury. Furthermore, therapeutically targeting them might be a novel approach for the treatment of keen articular cartilage injury.

show abstract

“…Because of the excellent tissue contrast provided by MRI, it can reveal musculoskeletal changes that are not visible on X-rays, as well as allowing the identification of the lesions that are most suitable for biopsy ( 1 , 8 - 11 ) . On MRI, nodular sarcoidosis has a characteristic appearance that can facilitate its accurate diagnosis-it typically consists of central areas of fibrosis that show low signal intensity in all sequences, together with peripheral areas of granulomas that show high signal intensity in T2weighted sequences and contrast enhancement ( 1 , 6 ) -findings collectively known as a "black star".…”

mentioning

confidence: 99%

Sarcoidosis: when the initial manifestations are musculoskeletal symptoms

Reis

Duarte²,

Alvarenga

et al. 2018

Radiol Bras

View full text Add to dashboard Cite

Anthropometric study of the knee in patients with osteoarthritis: intraoperative measurement versus magnetic resonance imaging

Cited by 18 publications

References 28 publications

Morphologic Features of the Distal Femur and Proximal Tibia: A Cross-Sectional Study

Morphologic Features of the Distal Femur and Proximal Tibia: A Cross-Sectional Study

Elevated levels of interleukin-1β, interleukin-6, tumor necrosis factor-α and vascular endothelial growth factor in patients with knee articular cartilage injury

Sarcoidosis: when the initial manifestations are musculoskeletal symptoms

Contact Info

Product

Resources

About