Anthropometric characteristics, high prevalence of undernutrition and weight loss: impact on outcomes in patients with adolescent idiopathic scoliosis after spinal fusion

Tarrant, Roslyn; Nugent, Mary; Nugent, Anne P.; Queally, Joseph M.; Moore, David P.; Kiely, Patrick

doi:10.1007/s00586-014-3622-2

Cited by 17 publications

(19 citation statements)

References 30 publications

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“…The pooled average early SSI rate among 14,517 patients was 2.1% (median, 2.6%; range, 0.5%–16.7%) [11,13,20,22,25,32,78,82–84,86,142,147,156,164,167,170,171] compared with 0.8% (median, 0.9%; range, 0.1%–4.7%) for pooled average late SSI rate among 12,238 patients [11,13,54,83,167,171]. In terms of specific types of spine operations, 52 studies evaluated SSI rates among patients who underwent spinal fusion [9,10,14,15,21,24,27,30,33,42,43,46,52,56,58,62,63,68–70,72,75,76,92,103,105,107–109,111,113–115,119,120,123,125,128,133,139,141–144,146,150,151,157,161,162,164,173]. The pooled average SSI rate was calculated to be 1.6% (median, 2.8%; range, 0.2%–18.3%) based on 64 cohorts comprising a total of 212,639 patients.…”

Section: Resultsmentioning

confidence: 99%

“…A total of 39 studies evaluating S. aureus SSI rates among patients who underwent spine operations of interest were included in this study (Table 1A) [6,7,10–15,32,37,45,47,48,52,53,62,77,84,90,91,101,103,111–113,117,122,126,129,132,137,138,140,146,155,160,164,167,173]. The pooled average S. aureus SSI rate was calculated to be 1% (median, 2%; range, 0.02%–10%) based on 42 cohorts evaluating a total of 112,135 patients.…”

Section: Resultsmentioning

confidence: 99%

“…An assessment of the S. aureus SSI rates after specific types of spine operations was only possible for spinal fusion and instrumented spinal fusion because of availability of data. On the basis of nine studies with nine cohorts consisting of a total of 9,604 patients who underwent spinal fusion, the calculated pooled average rate was 1.8% (median, 2.6%; range, 1.1%–8.3%) [14,15,52,62,103,113,146,164,173]. According to 13 studies consisting of 14 cohorts with a total of 14,835 patients who underwent instrumented spinal fusion, the calculated pooled average rate was 1.4% (median, 2%; range, 0.1%–10%) [6,37,48,77,84,90,101,112,122,126,132,137,160].…”

Section: Resultsmentioning

confidence: 99%

“…According to 13 studies consisting of 14 cohorts with a total of 14,835 patients who underwent instrumented spinal fusion, the calculated pooled average rate was 1.4% (median, 2%; range, 0.1%–10%) [6,37,48,77,84,90,101,112,122,126,132,137,160]. The pooled average contribution of S. aureus infections to spinal SSIs was calculated to be 49.3% (median, 50%; range, 16.7%–100%; 2,272 SSIs) [6,7,10–15,32,37,45,47,48,52,53,62,77,84,90,91,101,103,111–113,117,122,126,129,132,137,138,140,146,155,160,164,167,173]. …”

Section: Resultsmentioning

confidence: 99%

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Burden of Surgical Site Infections Associated with Select Spine Operations and Involvement ofStaphylococcus aureus

Patel¹,

Khoury²,

Girgenti

et al. 2017

Surgical Infections

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Background: Spine operations may be indicated for treatment of diseases including vertebral injuries, degenerative spinal conditions, disk disease, spinal misalignments, or malformations. Surgical site infection (SSI) is a clinically important complication of spine surgery. Staphylococcus aureus, including methicillin-resistant Staphylococcus aureus (MRSA), is a leading cause of post-spinal SSIs.Methods: PubMed and applicable infectious disease conference proceedings were searched to identify relevant published studies. Overall, 343 full-text publications were screened for epidemiologic, mortality, health care resource utilization, and cost data on SSIs associated with specified spine operations.Results: Surgical site infection rates were identified in 161 studies from North America, Europe, and Asia. Pooled average SSI and S. aureus SSI rates for spine surgery were 1.9% (median, 3.3%; range, 0.1%–22.6%) and 1.0% (median, 2.0%; range, 0.02%–10.0%). Pooled average contribution of S. aureus infections to spinal SSIs was 49.3% (median, 50.0%; range, 16.7%–100%). Pooled average proportion of S. aureus SSIs attributable to MRSA was 37.9% (median, 42.5%; range, 0%–100%). Instrumented spinal fusion had the highest pooled average SSI rate (3.8%), followed by spinal decompression (1.8%) and spinal fusion (1.6%). The SSI-related mortality rate among spine surgical patients ranged from 1.1%–2.3% (three studies). All studies comparing SSI and control cohorts reported longer hospital stays for patients with SSIs. Pooled average SSI-associated re-admission rate occurring within 30 d from discharge ranged from 20% to 100% (four studies). Pooled average SSI-related re-operation rate was 67.1% (median, 100%; range, 33.5%–100%). According to two studies reporting direct costs, spine surgical patients incur approximately double the health care costs when they develop an SSI.Conclusions: Available published studies demonstrate a clinically important burden of SSIs related to spine operations and the substantial contribution of S. aureus (including MRSA). Preventive strategies aimed specifically at S. aureus SSIs could reduce health care costs and improve patient outcomes for spine operations.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Burden of Surgical Site Infections Associated with Select Spine Operations and Involvement ofStaphylococcus aureus

Patel¹,

Khoury²,

Girgenti

et al. 2017

Surgical Infections

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“…1,2 Albumin is the most abundant serum protein and preoperative hypoalbuminemia is a factor that is intimately related to perioperative morbidity and mortality since it affects the vascular diffusion of nutrients, which impacts the immunological system and the maintenance of homeostasis. 3,4 Vitamin D is another important nutrient, fundamental to mineral homeostasis and bone metabolism.…”

Section: Introductionmentioning

confidence: 99%

Correlation Between Nutritional Status and Clinical Results in Patients Undergoing Spinal Surgery

et al. 2017

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Objective: To investigate the relationship between preoperative vitamin D and albumin levels and postoperative quality of life in patients undergoing spinal surgery. Methods: Patients undergoing thoracic and lumbar spine surgery were evaluated in this prospective study. Their vitamin D and albumin levels were assessed before surgery and quality of life was measured by two questionnaires, Oswestry Disability Index (ODI) and Scoliosis Research , one year after the procedure. Data on infection occurrence and healing time were collected. Preoperative nutritional values and patients' quality of life were analyzed using the chi-square test and ANOVA for albumin and vitamin D, respectively. The relationship among nutritional status, healing time, and the occurrence of infection was evaluated by the Pearson correlation coefficient. Results: Forty-six patients were included and their mean nutritional values were 19.1 (6.6) ng/mL for vitamin D and 3.9 (0.6) g/dL for albumin [mean (standard deviation)]. No association was found between vitamin D and quality of life of patients measured by ODI (p=0.534) and SRS-22 (p=0.739) questionnaires. There was also no association between albumin levels and quality of life measured by ODI (p=0.259) and SRS-22 (p=0.076) questionnaires. No correlation was found between the healing time or occurrence of infection and nutritional values. Conclusions: There was no association between vitamin D and albumin levels and the surgical result, according to the patient's perception, besides the occurrence of complications with the surgical wound.Keywords: Spine; Serum albumin; Vitamin D; Surgical wound infection; Quality of life. 19,1 (6,6) ng/ml para vitamina D e 3,9 (0,6) g/dl para albumina [média (desvio-padrão)]. Não foi encontrada associação entre os níveis de vitamina D e qualidade de vida dos pacientes medidos pelos questionários ODI (p = 0,739). Também não houve associação entre níveis de albumina e qualidade de vida medidos pelos questionários ODI (p = 0,076 ODI (p = 0,739). También no hubo asociación entre los niveles de albúmina y la calidad de vida medidos por los cuestionarios ODI (p = 0,076) RESUMO Objetivo: Investigar a relação entre os níveis de vitamina D e albumina pré-operatórios e qualidade de vida pós-operatória em pacientes submetidos a cirurgia de coluna. Métodos: Pacientes submetidos a cirurgia de coluna nos níveis torácico e lombar foram avaliados neste estudo prospectivo. Seus níveis de vitamina D e albumina foram avaliados antes da cirurgia e a qualidade de vida foi medida por meio de dois questionários, Oswestry Disability Index (ODI) e Scoliosis Research Society -22 (SRS-22), um ano após o procedimento. Os dados sobre ocorrência de infecção e tempo de cicatrização foram coletados. Os valores nutricionais pré-operatórios e a qualidade de vida dos pacientes foram analisados usando o teste de qui-quadrado e ANOVA para albumina e vitamina D, respectivamente. A relação entre o estado nutricional e o tempo de cicatrização e a ocorrência de infecção foram avaliados pelo coe...

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Low BMI (< 10th percentile) increases complications and readmissions after posterior spinal fusion in adolescent idiopathic scoliosis

2021

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Anthropometric characteristics, high prevalence of undernutrition and weight loss: impact on outcomes in patients with adolescent idiopathic scoliosis after spinal fusion

Cited by 17 publications

References 30 publications

Burden of Surgical Site Infections Associated with Select Spine Operations and Involvement ofStaphylococcus aureus

Burden of Surgical Site Infections Associated with Select Spine Operations and Involvement ofStaphylococcus aureus

Correlation Between Nutritional Status and Clinical Results in Patients Undergoing Spinal Surgery

Low BMI (< 10th percentile) increases complications and readmissions after posterior spinal fusion in adolescent idiopathic scoliosis

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