Anthropometric characteristics and cardiometabolic risk factors in a sample of urban-dwelling adults in Senegal

Fontbonne, Annick; Cournil, Amandine; Cames, Cécile; Mercier, Sabine; Coly, Aminata Ndiaye; Lacroux, Annie; Dupuy, Anne‐Marie; Diop, S; Cristol, Jean Paul; Bork, Kirsten

doi:10.1016/j.diabet.2010.07.008

Cited by 10 publications

(10 citation statements)

References 19 publications

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“…Triglycerides were low and remained so irrespective of obesity status. This is consistent with studies showing that low HDL-C is a major dyslipoproteinemia phenotype in obese Africans [33, 45]. In fact, studies show a gradual decrease in HDL-C levels in Africa, over the last three decades [45–47].…”

Section: Discussionsupporting

confidence: 90%

“…The significantly higher relative risk of onset of dyslipoproteinemia in AO men (not significant in women) over the followup period, even in the adjusted model, suggests that AO as currently defined using nonspecific cutoffs may be associated with higher CMR in men than women. This is consistent with a recent cross-sectional study in Senegal that reported less favourable CMR profiles in men than women in general, with lower HDL-C concentrations [33]. According to a recent review, higher HDL-C may be considered a gender-specific protective factor in women [34].…”

Section: Discussionsupporting

confidence: 89%

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Four-Year Trends in Cardiometabolic Risk Factors according to Baseline Abdominal Obesity Status in West-African Adults: The Benin Study

Sossa

Delisle

Aguèh³

et al. 2012

Journal of Obesity

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The study examined whether abdominal obesity (AO) according to waist circumference was associated with more unfavourable changes in other cardiometabolic risk (CMR) factors in sub-Saharan Africans. The study included 541 randomly selected and apparently healthy subjects (50% women) aged 25–60 years. Complete data at baseline, 24, and 48 months later was available in 366 subjects. AO was associated with higher CMR at baseline and over the follow-up period, except for high blood pressure. A significantly higher incidence of high ratio of total cholesterol : HDL-cholesterol (TC/HDL-C) was associated with AO. Controlling for WC changes, age, baseline diet, and lifestyles, the relative risk (RR) of low HDL-C and high TC/HDL-C was 3.2 (95% CI 1.06–9.61) and 7.4 (95% CI 2.01–25.79), respectively, in AO men; the RR was not significant in women. Over a four-year period, AO therefore appeared associated with an adverse evolution of cholesterolemia in the study population.

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Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 89%

Four-Year Trends in Cardiometabolic Risk Factors according to Baseline Abdominal Obesity Status in West-African Adults: The Benin Study

Sossa

Delisle

Aguèh³

et al. 2012

Journal of Obesity

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“…56 Additional research in Benin and Senegal has found support for a link between increased body fat and fat distribution in metabolic risk factors for cardiovascular disease. 57,58 A recent systematic review of hypertension literature across Sub-Saharan Africa, showed that while prevalence was highly variable between countries, on average rates were rising, and were higher in urban areas, 59 a similar pattern being found for hypercholesterolemia. 60 The body of literature reviewed above (and provided in greater depth by other contributions to this special issue) suggests that there is ample evidence for connections between globalization and urbanization, diet, overweight and obesity, and NCD prevalence.…”

Section: Global Food Environment and Noncommunicable Diseasementioning

confidence: 87%

Urbanization and International Trade and Investment Policies as Determinants of Noncommunicable Diseases in Sub-Saharan Africa

Schram

Labonté

Sanders

2013

Progress in Cardiovascular Diseases

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“…In our study, for early detection of cardiometabolic risk we determined WC cut offs to predict at least one other component of the MS as study mentioned that cluster of risk factors do not add anything to the predictive value of the individual components of the syndrome The low WC cut offs in men compared to women observed in our study is consistent with studies of Lemieux et al [37] who reported that men are on average twice as much visceral abdominal fat than premenopausal women. In convergence, Fontbone et al observed in Senegal, a more favorable RCM profile in women compared to men, which showed a high prevalence of low HDL cholesterol levels [38], while high levels of HDLcholesterol are considered as a specific protection factor sex for women [39]. However, during menopause, lipid profile of women becomes more atherogenic and is associated with weight gain [40].…”

Section: Discussionmentioning

confidence: 99%

Determination of the Optimal Waist Circumference Cut-Off Points in Benin Adults

Aguèh¹,

Sossa²,

Ouendo³

et al. 2015

OJEpi

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Obesity is an independent risk factor for chronic diseases such as diabetes, cardiovascular diseases and certain cancers. Early detection of abdominal obesity followed by appropriate interventions will prevent associated diseases. The objective was to determine optimal waist circumference (WC) cutoff points predictive of at least one other component of metabolic syndrome in Benin adults. This longitudinal and observational study included at the baseline 541 apparently healthy subjects aged 25-60 years randomly selected in the largest city of Cotonou (n = 200), the smaller-size city of Ouidah (n = 171) and rural surroundings of Ouidah (n = 170) in Benin. Components of the metabolic syndrome considered along with abdominal obesity were high blood pressure, high fasting glycaemia, low HDL-cholesterol and high triglycerides as defined by the Joint Interim Statement. After the baseline survey, the subjects were followed-up for four years. Complete data at baseline and four years later were available in 416 subjects. The receiver operating characteristic (ROC) curve for waist circumference to predict at least one other component of the metabolic syndrome was plotted and the Youden index was used to define the optimal cutoffs of WC. At the baseline of the study, the optimal WC cutoff point to predict the presence of at least one other component of the metabolic syndrome was 80 cm for men (sensitivity = 0.62, specificity = 0.65); the area under the ROC curve was 0.67 (IC 95%: 0.61-0.74). In women, the optimal WC cutoff point was 90 cm (sensitivity = 0.54, specificity = 0.80), and the area under the ROC curve was 0.68 (IC 95%: 0.62-0.75). These optimal cutoffs were similar four years later. Optimum WC cutoff points for both men and women in Benin differ from those currently recommended for sub-Saharan Africans. Therefore, waist circumference cutoff points for abdominal obesity need to be reconsidered for these populations.

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Anthropometric characteristics and cardiometabolic risk factors in a sample of urban-dwelling adults in Senegal

Cited by 10 publications

References 19 publications

Four-Year Trends in Cardiometabolic Risk Factors according to Baseline Abdominal Obesity Status in West-African Adults: The Benin Study

Four-Year Trends in Cardiometabolic Risk Factors according to Baseline Abdominal Obesity Status in West-African Adults: The Benin Study

Urbanization and International Trade and Investment Policies as Determinants of Noncommunicable Diseases in Sub-Saharan Africa

Determination of the Optimal Waist Circumference Cut-Off Points in Benin Adults

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