Anthracene Crystallization Induced by Single-Shot Femtosecond Laser Irradiation:  Experimental Evidence for the Important Role of Bubbles

Nakamura, Kazuhiko; Hosokawa, Yoichiroh; Masuhara, Hiroshi

doi:10.1021/cg060631q

Cited by 55 publications

(86 citation statements)

References 22 publications

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“…The sudden pressure rise leads to an emission of a shock wave and bubbling, for example, the creation of cavitation bubbles by transient boiling [17][18][19][20] and subsequent long-lasting bubbles that are composed of gas products from the photodecomposition of solute and solvent molecules [21]. Recently, we and another group quantitatively determined threshold energies of nucleation and laser-induced bubbling using simple organic molecules and proteins [22][23][24][25]. The results clearly showed that nucleation occurs when the laser irradiation has energy above the threshold for the generation of laser-induced bubbling.…”

Section: Introductionmentioning

confidence: 99%

Femtosecond laser-induced nucleation of protein in agarose gel

Yoshikawa

Murai

Sugiyama

et al. 2009

Journal of Crystal Growth

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Section: Introductionmentioning

confidence: 99%

Femtosecond laser-induced nucleation of protein in agarose gel

Yoshikawa

Murai

Sugiyama

et al. 2009

Journal of Crystal Growth

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“…7 (2013)A more direct confirmation of dynamics of this femtosecond laser-induced crystallization was demonstrated for simple solution system; anthracene in cyclohexane. 89 Its crystallization is very easy and crystal growth is fast, so that it is possible to monitor the growing within 1 s. A single shot femtosecond laser pulse with a pulse energy higher than above 3.1¯J/pulse was irradiated into a sufficiently supersaturated solution, and then we found that anthracene crystallization was induced at the vicinity of the laser focal point immediately after the irradiation. The threshold of crystallization was in agreement with that of the laser-induced bubbling.…”

Section: Crystallization Of Molecules and Proteins By Femtosecond Lasmentioning

confidence: 90%

Time-Resolved Spectroscopic and Imaging Studies on Laser Ablation of Molecular Systems: From Mechanistic Study to Bio/Nano Applications

Masuhara

2013

Bulletin of the Chemical Society of Japan

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Studies on laser ablation of polymer films, molecular crystals in solution, protein solution, and culture media containing living cells are summarized and considered. Dynamics and mechanism of laser ablation were systematically studied by utilizing time-resolved spectroscopy and imaging; femtosecondnanosecond transient absorption and emission spectroscopy, nanosecond shadowgraphy, nanosecondnanometer interferometry, femtosecond surface light scattering imaging. It was confirmed by integrating both data that primary processes of laser ablation can be well understood in the framework of Jablonski diagram. For nanosecond laser ablation of doped polymers, it was demonstrated that cyclic multiphoton absorption is an efficient photothermal conversion process leading to photothermal ablation. For femtosecond laser ablation of dye films, transient pressure mechanism was proposed indicating photomechanical ablation. As applications of laser ablation, nanoparticle preparation, protein crystallization, and manipulation of living cells are presented. Laser ablation of molecular crystals in poor solvent gives small fragments whose size are in a few tens nm. The fabricated nanocolloids are stable without adding detergents and their size was the smallest as nanoparticles produced by the top-down-method. Multiphoton laser ablation of water generates local impulsive force due to bubble formation, shockwave propagation, and local convection flow. The force triggers molecular and protein crystallization in their supersaturated solutions, whose mechanisms are described and considered. The impulsive force is also very useful for manipulating living cells and its high potential was confirmed by examining cell functions such as division, differentiation, death, and migration. Finally summary and future plan are presented.Studies on molecular spectroscopy and photochemistry introduced lasers very early in 1960's and used them as light sources for spectroscopic measurements as well as for inducing photochemical reactions. When chemists started to use pulsed lasers, they soon became aware that laser irradiation induced vaporization, decomposition, and fragmentation of materials and found that the irradiated surface was etched. The left patterns on the colored papers were practically used to confirm optical alignment in experimental setups before infrared (IR) viewer became popular. Later this laser-induced phenomenon was called laser ablation by Srinivasan, 1 and its systematic application was quickly developed to fabricate microstructures of various materials by electronics engineers and to microsurgery by medical doctors. Laser ablation is made possible by applying pulsed lasers and never brought out by weak continuous wave (CW) laser even when its irradiation continues for 1 year. Laser ablation is one of representative nonlinear photochemical phenomena and has a threshold with respect with laser fluence. Initially most of laser ablation studies were carried out for metals, semiconductors, ceramics, and glasses, 2 while organic materi...

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“…Interestingly, the rate of nucleation and crystal growth determine the time to crystallization in the solution [48]. Indeed, gas bubbles can have a positive effect on crystallization, as commented by Nakamura [49], Matsumoto [50] and Deora [51]. During bubble formation and rupture, several processes may trigger crystallization.…”

Section: Morphologymentioning

confidence: 99%

Combined control of morphology and polymorph in spray drying of mannitol for dry powder inhalation

Lyu

Liu

Zhang

et al. 2017

Journal of Crystal Growth

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The morphology and polymorphism of mannitol particles were controlled during spray drying with the aim of improving the aerosolization properties of inhalable dry powders. The obtained microparticles were characterized using scanning electron microscopy, infrared spectroscopy, differential scanning calorimetry, powder X-ray diffraction and inhaler testing with a next generation impactor. Mannitol particles of varied -mannitol content and surface roughness were prepared via spray drying by manipulating the concentration of NH 4 HCO 3 in the feed solution. The bubbles produced by NH 4 HCO 3 led to the formation of spheroid particles with a rough surface. Further, the fine particle fraction was increased by the rough surface of carriers and the high -mannitol content.Inhalable dry powders with a 29.1 ± 2.4% fine particle fraction were obtained by spray-drying using 5% mannitol (w/v)/2% NH 4 HCO 3 (w/v) as the feed solution, proving that this technique is an effective method to engineer particles for dry powder inhalation.

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Anthracene Crystallization Induced by Single-Shot Femtosecond Laser Irradiation: Experimental Evidence for the Important Role of Bubbles

Cited by 55 publications

References 22 publications

Femtosecond laser-induced nucleation of protein in agarose gel

Femtosecond laser-induced nucleation of protein in agarose gel

Time-Resolved Spectroscopic and Imaging Studies on Laser Ablation of Molecular Systems: From Mechanistic Study to Bio/Nano Applications

Combined control of morphology and polymorph in spray drying of mannitol for dry powder inhalation

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