Anthocyanins from Lycium ruthenicum Murray inhibit HCC tumor angiogenesis and promote autophagic apoptosis through AMPK/PI3K/AKT/mTOR pathway
Tingting Wei,
Jiajie Cheng,
Hongli Fan
et al.
Abstract:Purpose
Angiogenesis is a crucial factor in the initiation, progression and metastasis of tumor. The exploration for novel anti-angiogenic agents from natural sources has garnered significant attention. Our previous study confirmed the inhibitory effects of anthocyanins obtained from Lycium ruthenicum Murray (ALR) on the growth and metastasis of HepG2 cells, yet its potential to suppress neovascularization in hepatocellular carcinoma (HCC) remains unknown. This research aimed to assess the anti-angiogenic eff… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.