Anthelmintics for people with neurocysticercosis

Abba, Katharine; Ramaratnam, Sridharan; Ranganathan, Lakshmi Narasimhan

doi:10.1002/14651858.cd000215.pub3

Cited by 44 publications

(31 citation statements)

References 43 publications

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“…For viable parenchymal disease, antiparasitic medications increase the speed of radiographic resolution22 and decrease seizure recurrence 23. Albendazole (at 15 mg/kg/day by mouth for 8–15 days) is slightly more efficacious than praziquantel (at 50–75 mg/kg/day by mouth for 15 days) 24.…”

Section: Discussionmentioning

confidence: 99%

Under seize: neurocysticercosis in an immigrant woman and review of a growing neglected disease

et al. 2015

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Summary Neurocysticercosis (NCC) is a significantly neglected tropical disease and, with increasing globalisation, a notable emerging infection in the developed world. We describe a case of ventricular NCC in a 22-year-old Mexican-American woman with a history of seizures, who presented with 2 weeks of headaches and intermittent fevers progressing to altered mental status and vomiting. Initial imaging revealed a cystic mass at the posteroinferior aspect of the third ventricle superior to the aqueduct of Sylvius, calcifications scattered throughout the parenchyma, and enlargement of the lateral and third ventricles. Initial laboratories were unrevealing and serum investigations for Taenia solium antibody were negative, but T. solium antibody was subsequently returned positive from cerebrospinal fluid. This case highlights important issues regarding the clinical presentation, diagnostic evaluation and treatment of NCC relevant to providers not only in areas with endemic disease but, importantly, in locales with diverse immigrant populations.

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Section: Discussionmentioning

confidence: 99%

Under seize: neurocysticercosis in an immigrant woman and review of a growing neglected disease

et al. 2015

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“…Contemporary diagnostic criteria for neurocysticercosis have been established [10], and the medical treatment of neurocysticercosis, including considerations relating to the use of antihelminthic [1] and cysticidal agents, steroids, and antiepileptic drugs, have been reviewed by a number of groups [12,13,28,21]. Neurosurgical indications and approaches have also been studied [20,7,24,30,15] and reviewed by several authors [25,29].…”

Section: Discussionmentioning

confidence: 99%

Third-ventricular neurocysticercosis: hydraulic maneuvers facilitating endoscopic resection

2013

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Neurocysticercosis, infection of the central nervous system with the larval cysts of the pork tapeworm, Taenia solium, is the most common parasitic disease of the central nervous system. The disease is a major global cause of acquired epilepsy and may also manifest as intracranial hypertension due to mass effect from large cysts, or to cerebrospinal fluid flow obstruction by intraventricular cysts or inflammation of the subarachnoid space. While the condition is endemic in several regions of the world and has been appreciated as a public health problem in such regions for several decades, its emergence in the United States in areas far from the Mexican border is a more recent phenomenon. We present a case of surgically corrected acute hydrocephalus in a recent Haitian emigrant child due to a third-ventricular neurocysticercal cyst complex, and describe the endoscope-assisted en bloc removal of the complex, together with hydraulic maneuvers facilitating removal of the intact cyst.

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“…In general, eradication therapy with cysticidal agents benefit symptomatic patients with multiple, live (non-calcified) cysticerci. A meta-analysis by Abba et al 25 found that administration of cysticidal therapy in patients with viable lesions reduced the number of lesions. Another study by Kalra et al 26 concluded that the combination of albendazole and dexamethasone increases resolution of NCC lesions and reduces the risk of recurrence of seizure among children presenting one or two ring-enhancing lesion on CT.…”

Section: Discussionmentioning

confidence: 99%

Transient cortical blindness as a manifestation of solitary cysticercus granuloma

Hussain

2012

BMJ Case Reports

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Neurocysticercosis is recognised as a significant cause of neurological morbidity in endemic regions. The wide range of pleomorphic and non-specific neurological manifestations of neurocysticercosis must be kept in mind by physicians, as the disease has shown resurgence in developed countries. When an atypical presentation of an unusual tropical disease occurs in non-endemic regions, the diagnosis is often missed. We describe a case of a 4-year-old girl who presented with a history of transient bilateral loss of vision with headache and vomiting. Brain MRI revealed the presence of a single cysticercus granuloma in the occipital lobe. A diagnosis of symptomatic occipital lobe seizure secondary to neurocysticercosis was made. She was given a course of albendazole. There was no recurrence of symptoms at 3 years follow-up. Occipital seizures that are associated with ictal amaurosis closely mimic basilar migraine. Such cases benefit from neuroimaging in order to rule out the underlying structural causes.

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Anthelmintics for people with neurocysticercosis

Abstract: Trusted evidence. Informed decisions. Better health.

Cited by 44 publications

References 43 publications

Under seize: neurocysticercosis in an immigrant woman and review of a growing neglected disease

Under seize: neurocysticercosis in an immigrant woman and review of a growing neglected disease

Third-ventricular neurocysticercosis: hydraulic maneuvers facilitating endoscopic resection

Transient cortical blindness as a manifestation of solitary cysticercus granuloma

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