Anthelmintic activity of Ethanolic extract of whole plant of Eupatorium odoratum. L

Patel, Jitendra; Kumar, Gaurav; Qureshi, Md. Shamim; Jena, Prabhat Kumar

doi:10.5138/ijpm.2010.0975.0185.02020

Cited by 32 publications

(21 citation statements)

References 25 publications

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“…Among the two pure compounds analyzed PI showed more potent activity than PII. The results obtained in the present study are in accordance with the earlier studies of Sucheta et al, (2011);Jitendra et al, (2010); Arasan et al (2010) and Vidyadhar et al (2010) in which the ethanol extract showed significant anthelmintic activity against tested earth warms.…”

Section: Discussionsupporting

confidence: 83%

In vitro Anthelmintic Activity of Different Extracts of Memecylon umbellatumBurm.

Asha¹,

Krishnappa²,

Kenchappa³

2016

Sci. Technol. Arts Res. J.

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In the present study, the possible anthelminitic effects of different extracts (petroleum ether, chloroform, and ethanol) and two isolated compounds β Sitosterol (PII) from the leaves of Memecylon umbellatum Pheretima Posthuma was investigated by in vitro (25, 50, 100mg/ml) of all extracts were tested and results were expressed in terms of time for paralysis and time for death of worms. From the activity results it was found that the ethanolic extract and pure compound PI having the equipotent activity with standard drug albendazole. Form the observations made higher concentration of extract produced paralytic effect much earlier and the time to death was shorter for all worms.

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Section: Discussionsupporting

confidence: 83%

In vitro Anthelmintic Activity of Different Extracts of Memecylon umbellatumBurm.

Asha¹,

Krishnappa²,

Kenchappa³

2016

Sci. Technol. Arts Res. J.

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“…Parasites will also die if they become paralyzed and temporarily lose their ability to maintain their position in the gut. Anthelmintics can act by also binding to gastrointestinal tract free proteins of the worms, thereby ultimately causing death (Patel et al, 2010).…”

Section: Resultsmentioning

confidence: 99%

Evaluation of in vitro anthelmintic activity of extracts of jasminum sessiliflorum

Philip

Krishnasamy

Abraham

2019

ijrps

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Plant preparations are most popular from ancient times for the treatment of various diseases. The ancient people had an appreciable on the application and usage of plant preparations for the common ailments. Based on the investigation, it has been found that various species of this plant has been used as an anthelmintic. The extracts of Jasminum sessiliflorum was investigated for anthelmintic potential using earthworms, Pheretima posthuma. Different concentration of plant extracts were used for the evaluation. Albendazole (10 mg/ml) was used as reference standard drug. The method employs the determination of paralysis time and death time of the worms and these results were recorded. Extracts showed significant activity. The ethanolic extract was found to be most efficient.

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“…It is also used for the treatment of various ailments, such as amenorrhea, catarrh, cold-associated nasal congestion, diabetes, diarrhoea, fever, pertussis and rheumatism, and as a vermifuge (Goodall and Erasmus 1996). Other pharmacological properties of this plant include anthelminthic (Patel et al 2010), antimalarial (Ongkana 2003), analgesic (Chakraborty et al 2011), anti-inflammatory, antipyretic, antispasmodic (Oludare et al 2000), antimycobacterial, insecticidal, antioxidant (Phan et al 2001a), anti-gonorrhoeal (Caceres et al 1995), fungicidal, diuretic (Gopinath et al 2009), blood coagulating (Triaratana et al 1991), and antimicrobial effects (Borges et al 2016). However, at present there is only limited information available pertaining to the wound healing properties of the plant (Biswal et al 1997).…”

Section: Original Papermentioning

confidence: 99%

Efficacy of Chromolaena odorata leaf extracts for the healing of rat excision wounds

Vijayaraghavan¹,

Rajkumar²,

Ali-Seyed³

2017

Vet. Med.

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Injury to the soft tissues is followed by wound healing, which consists of four stages: haemostasis, inflammation, proliferation and remodelling. Chromolaena odorata is a weed that is traditionally used for the treatment of various ailments in humans and animals. The present study was aimed at exploring the wound healing potential of aqueous and ethanolic extracts of C. odorata in a rat excision wound model. This investigation involved phytochemical screening and in vitro analyses of various parameters such as antioxidant activity, lipid peroxide inhibitory activity and the effects of extracts on contraction and epithelialisation of the rat excision wounds. The phytochemical screening of both ethanolic and aqueous extracts showed that they were rich in secondary metabolites such as alkaloids, flavonoids, tannins, saponins, terpenoids, anthraquinones, cardiac glycosides and carbohydrates. The aqueous extract showed high antioxidant and lipid peroxide inhibitory activity, while the ethanolic extract showed high total phenol content and hydrogen peroxide inhibitory activity at concentrations of 50, 100 and 250 μg/ml. Our results also indicate that the most effective concentration of the C. odorata extract for excision wound healing was 5.0% (w/w). C. odorata-treated groups exhibited a faster reduction in wound area compared to control and Betadine-treated groups. In addition, the topical application of C. odorata extract increased collagen synthesis and its stabilisation at the wound site, as evidenced by the increase in hydroxyproline and hexosamine levels and expression of collagen. The present investigation demonstrates that aqueous and ethanolic extracts of C. odorata of varying concentrations promote an accelerated wound healing process and might represent a novel healing agent. Our findings are of potential clinical relevance and might be highly beneficial for drug discovery and development in the area of both human and veterinary medicine.

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Anthelmintic activity of Ethanolic extract of whole plant of Eupatorium odoratum. L

Cited by 32 publications

References 25 publications

<i>In vitro </i>Anthelmintic Activity of Different Extracts of <i>Memecylon umbellatum</i>Burm.

<i>In vitro </i>Anthelmintic Activity of Different Extracts of <i>Memecylon umbellatum</i>Burm.

Evaluation of in vitro anthelmintic activity of extracts of jasminum sessiliflorum

Efficacy of Chromolaena odorata leaf extracts for the healing of rat excision wounds

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