Anterior urethral valves and diverticula in children: a result of ruptured Cowper's duct cyst?

McLellan, Dawn L.; Gaston, Michael V.; Diamond, David A.; Lebowitz, Robert L.; Mandell, James; Atala, Anthony; Bauer, Stuart B.

doi:10.1111/j.1464-410x.2004.04854.x

Cited by 56 publications

(57 citation statements)

References 23 publications

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“…However, current opinion recommends open intervention for certain populations, such as children with large diverticula and inadequate spongiosum. In such cases, diverticulectomy should be considered (9,(33)(34)(35). In the infant population where severe reflux exists due to an anterior urethral valve phenomenon secondary to syringocele, urinary diversion and vesicostomy should be considered (36,37).…”

Section: Treatment Of Syringocelesmentioning

confidence: 99%

Current diagnosis and management of syringocele: a review

Melquist¹,

Sharma²,

Sciullo³

et al. 2010

Int. braz j urol.

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Cowper's syringocele is a rare but an under-diagnosed cystic dilation of the Cowper's ducts and is increasingly being recognized in the adult population. Recent literature suggests that syringoceles be classified based on the configuration of the duct's orifice to the urethra, either open or closed, as this also allows the clinical presentations of 2 syringoceles to be divided, albeit with some overlap. Usually post-void dribbling, hematuria, or urethral discharge indicate open syringocele, while obstructive symptoms are associated with closed syringoceles. As these symptoms are shared by many serious conditions, a working differential diagnosis is critical. Ultrasonography coupled with retro and ante grade urethrography usually suffices to diagnose syringocele, but supplementary procedures -such as cystourethroscopy, computed tomography scan, and magnetic resonance imaging -can prove useful. Conservative observation is first recommended, but persistent symptoms are usually treated with endoscopic marsupialization unless contraindicated. Upon reviewing the literature, this paper addresses the clinical anatomy, classification, presentation, diagnosis, and treatment of syringoceles in further detail.

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Section: Treatment Of Syringocelesmentioning

confidence: 99%

Current diagnosis and management of syringocele: a review

Melquist¹,

Sharma²,

Sciullo³

et al. 2010

Int. braz j urol.

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“…Reviews in the literature depend on the size of the cavity, thickness of the dorsal wall and the integrity of the corpus spongiosum or other adequate supporting tissue layers. These large saccular diverticula with inadequate support from the corpus spongiosum may most benefit from open surgical excision and urethral reconstruction providing support of the spongy tissue [9]. The aim should be to completely excise the diverticulum, restore continuity of the urethra, and, if necessary, provide additional tissue to reinforce the repair and prevent a fistula to the skin.…”

Section: Discussionmentioning

confidence: 99%

Traumatic Urethral Diverticula: A Rare Malformation of the Male Urethra

Li¹,

Sa²,

Jin³

et al. 2013

Urol Int

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Urethral diverticula are pouches opening into the urethral canal that may be either acquired or congenital. Diverticula of the female urethra are fairly common. However, diverticula of the male urethra are relatively uncommon abnormalities. Clinical manifestation is frequently described with irritative and/or obstructive voiding symptoms or ventral bulging, but manifestation as a scrotal mass is extremely rare. We report a giant urethral diverticulum presenting as a scrotal mass in an adult male.

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“…Está relacionada com a produção de um líquido claro e viscoso, de pH alcalino que lubrifica a uretra e a glande, neutraliza a acidez da uretra e a secreção vaginal ácida da mulher (Orts 1967, Ninomiya et al 1995. No sêmen participa também como um fator necessário na coagulação e de defesa urogenital pela secreção de glicoproteínas, tais como o antígeno prostático específico (Pedron et al 1997, McLellan et al 2004, Chughtai et al 2005. Em outros mamíferos sua função é pouco conhecida.…”

Section: Introductionunclassified

Estereologia das glândulas bulbouretrais do coelho (Oryctolagus cuniculus) e da cobaia (Cavia porcellus)

Vásquez

Sol

2014

Pesq. Vet. Bras.

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As glândulas bulbouretrais (GBU) no coelho (Oryctolagus cuniculus) e na cobaia (Cavia porcellus) desempenham um papel importante na fisiologia reprodutiva. No entanto, seus aspectos histológico e estereológico são escassos. Assim, o objetivo desta pesquisa foi comparar características estereológicas entre as GBU do coelho e da cobaia como um primeiro passo para a compreensão das variáveis morfométricas que participam nos processos reprodutivos. Foram utilizados 5 coelhos e 5 cobaias adultos machos, saudáveis, obtidos do Biotério da Universidade de La Frontera, Temuco, Chile. A região pélvica foi dissecada isolando-se a GBU de cada animal. Determinou-se o peso e o volume de cada glândula. Estas foram fixadas em formalina tamponada durante 24 horas e incluídas em paraplast. Cortes seriados de 4 μm de espessura foram corados com HE para análise estereológica. A média de células glandulares na GBU do coelho foi 19,50 x 10(5)mm³ (DP 2,35) e da cobaia 10,57 x 10(5)mm³ (DP 2,07) e a porcentagem média de tecido glandular foi de 25,52% (DP 2,20) e 17,20% (DP 3,33), respectivamente. Todos os parâmetros estereológicos comparados tiveram uma diferença estatisticamente significativa (p<0,0001). Estas diferenças poderiam ser explicadas porque há maior proximidade celular do epitélio secretor, menor diâmetro do lúmen dos ácinos e da relação núcleo citoplasma na GBU do coelho. Assim, os ácinos da GBU apresentam maior quantidade de células por mm³ do que na GBU do coelho. Estes parâmetros podem ser influenciados por fatores hormonais, etários, sazonais e ambientais, entre outros. Considerar as características morfológicas da GBU nesses animais poderia condicionar o êxito da reprodução por parte do macho.

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Anterior urethral valves and diverticula in children: a result of ruptured Cowper's duct cyst?

Abstract: OBJECTIVETo review a series of children with anterior urethral valves and diverticula, to elucidate the pathophysiology and optimal management of this entity. PATIENTS AND METHODSNine cases (all boys; 1963 to 2003) were reviewed retrospectively.

Cited by 56 publications

References 23 publications

Current diagnosis and management of syringocele: a review

Current diagnosis and management of syringocele: a review

Traumatic Urethral Diverticula: A Rare Malformation of the Male Urethra

Estereologia das glândulas bulbouretrais do coelho (Oryctolagus cuniculus) e da cobaia (Cavia porcellus)

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