Anterior segment optical coherence tomography angle and vault analysis after toric and non-toric implantable collamer lens V4c implantation in patients with high myopia

Rosa, Guillermo Garcia-De la; Olivo-Payne, Andrew; Serna‐Ojeda, Juan Carlos; Salazar-Ramos, Maria Sandra; Lichtinger, Alejandro; Gomez-Bastar, Arturo; Ramírez-Miranda, Arturo; Navas, Alejandro; Graue-Hernández, Enrique O

doi:10.1136/bjophthalmol-2017-310518

Cited by 40 publications

(25 citation statements)

References 16 publications

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“…If we focus now on predictability, we can consider these procedures to be successful, since 90.6% and 93.9% of the eyes were within the ±0.50 and ± 1.00 D range of postoperative refractive error, respectively. Both values were also comparable and sometimes better (versus Ganesh et al [7], García-de-la-Rosa et al [10], and Niu et al [11]) than those found in previous studies (see Table 3). Similarly, SE was also good, being below a quarter of diopter (−0.09 ± 0.47D).…”

Section: Discussionsupporting

confidence: 74%

“…e search was limited to publications written in English. e date of the last electronic search was March 24, 2020. e literature search based on these criteria resulted in 8 relevant contributions being considered [5][6][7][8][9][10][11][12]. Table 2 summarizes the information about the sample size (number of eyes), patients' age, and SE values of these studies.…”

Section: Discussionmentioning

confidence: 99%

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Posterior-Chamber Phakic Intraocular Lens Implantation in Patients over 40 Years of Age

Tañá‐Rivero

Pastor-Pascual

Crespo

et al. 2020

Journal of Ophthalmology

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Purpose. To assess the efficacy, safety, and predictability of the Visian Implantable Collamer Lens (ICL) model having a central port in patients over 40 years of age. Methods. This study included 33 eyes from 21 patients who underwent V4c ICL implantation for the correction of myopia and myopic astigmatism. We assessed uncorrected (UDVA) and corrected (CDVA) distance visual acuity, refraction, intraocular pressure (IOP), endothelial cell density (ECD), vault, and adverse events occurring over a 1-year period. Results. Mean age of the patients at the time of implantation was 43.52 ± 4.49 years (range: 40 to 56 years). Efficacy and safety indexes were 1 and 1.09, respectively. Surgical outcomes for CDVA were as follows: no eye lost any lines, 19 eyes (57.58%) showed no CDVA changes, 7 eyes (21.21%) gained 1 line, 4 eyes (12.12%) gained 2 lines, and 3 eyes (9.09%) gained ≥3 lines. Mean postoperative spherical equivalent (SE) was −0.09 ± 0.47 D. A total of 29 eyes (87.8%) were within ±0.50 D and 31 eyes (93.9%) were within ±1.00 D of the desired SE. At 1-year, mean IOP was 15.27 ± 3.03 mmHg (range: 9 to 20 mmHg, p=0.12 pre vs. post) and mean ECD was 2516 ± 234 cells/mm2 (p=0.29 pre vs. post). Mean postoperative vault was 320 ± 136 μm, with 201–300 μm being the most prevalent vault range for 9 eyes (31.03%). None of the eyes showed a vault >701 μm. There were neither intraoperative nor postoperative complications; in fact, all ICL implantation procedures were uneventful. Conclusions. Our study’s findings support the use of this lens in patients over 40 years of age. A long follow-up period is advisable to monitor ICL position relative to the crystalline lens.

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Section: Discussionsupporting

confidence: 74%

Section: Discussionmentioning

confidence: 99%

Posterior-Chamber Phakic Intraocular Lens Implantation in Patients over 40 Years of Age

Tañá‐Rivero

Pastor-Pascual

Crespo

et al. 2020

Journal of Ophthalmology

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“…In this study, there was a negative correlation between the C-ICL and the ΔECD. Several reports [22][23][24][25][26] regarding the anterior chamber lens showed a decreased distance between the corneal endothelium and central ICL, which increased the loss of ECD. Two reports in 2017 emphasised the importance of C-ICL in reducing the loss of ECD.…”

Section: Discussionmentioning

confidence: 97%

Four-year observation of the changes in corneal endothelium cell density and correlated factors after Implantable Collamer Lens V4c implantation

Yang

Zhao

Zhao³

et al. 2020

Br J Ophthalmol

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BackgroundTo evaluate the changes in corneal endothelium cell density (ECD) and the correlated factors after Implantable Collamer Lens (ICL) V4c implantation.MethodsIn this retrospective, consecutive study, 48 eyes of 25 patients with myopia who underwent ICL V4c implantation were enrolled. Patients were followed up for at least 4 years, during which manifest refraction, uncorrected distance visual acuity, corrected distance visual acuity (CDVA), intraocular pressure, ECD, anterior chamber depth, anterior chamber volume (ACV), anterior chamber angle (ACA), vault and distance from the corneal endothelium to the central ICL (C-ICL) were measured. Spearman’s correlation analysis was used to identify variables correlated with changes in ECD, and generalised estimating equation model adjusting within-patient intereye correlations was used to predict changes in ECD.ResultsAll surgeries were performed safely with no complications during follow-up (average 52±2.9 months). Safety and efficacy indices were 1.23±0.22 and 1.04±0.16, respectively. No eyes had decreased CDVA, and 67% gained one or more lines. Further, 79% were within ±0.50 D, and 100% were within ±1.0 D of the attempted refraction. Additionally, a 4.03%±2.2% reduction in ECD compared with the preoperative value was observed at the last follow-up visit. Changes in ECD were significantly correlated with vault, C-ICL, change in ACA and change in ACV. Vault was the most significant factor for changes in ECD.ConclusionsICL V4c implantation is safe and effective for myopia correction. Anterior segment biometric parameters including the vault, ACA and C-ICL may influence changes in ECD; specifically, the vault plays a major role.

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“…This includes evaluation of pterygium [102], management guidance in ocular surface neoplasia [103], characterization of abnormalities associated with keratoconus [104-108], and evaluation of corneal wound healing [109-113]. The role of AS-OCT is also important in preoperative, intraoperative, and postoperative assessment of patients requiring corneal surgeries [111, 114-118]. Recently, application of intraoperative AS-OCT has been proven to be helpful in deep anterior lamellar keratoplasty [119-121], femtosecond cataract surgery [122], as well as during Descemet stripping automated endothelial keratoplasty (DSAEK) [123] and Descemet membrane endothelial keratoplasty (DMEK) [124, 125].…”

Section: Imaging and Ne(ur)ovascularizationmentioning

confidence: 99%

New Technologies in Clinical Trials in Corneal Diseases and Limbal Stem Cell Deficiency: Review from the European Vision Institute Special Interest Focus Group Meeting

et al. 2020

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To discuss and evaluate new technologies for a better diagnosis of corneal diseases and limbal stem cell deficiency, the outcomes of a consensus process within the European Vision Institute (and of a workshop at the University of Cologne) are outlined. Various technologies are presented and analyzed for their potential clinical use also in defining new end points in clinical trials. The disease areas which are discussed comprise dry eye and ocular surface inflammation, imaging, and corneal neovascularization and corneal grafting/stem cell and cell transplantation. The unmet needs in the abovementioned disease areas are discussed, and realistically achievable new technologies for better diagnosis and use in clinical trials are outlined. To sum up, it can be said that there are several new technologies that can improve current diagnostics in the field of ophthalmology in the near future and will have impact on clinical trial end point design.

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Anterior segment optical coherence tomography angle and vault analysis after toric and non-toric implantable collamer lens V4c implantation in patients with high myopia

Abstract: There is a significant reduction in the iridocorneal angle after ICL V4c implantation. Furthermore, there is a change under mesopic conditions in both the iridocorneal angle and vault during long-term follow-up.

Cited by 40 publications

References 16 publications

Posterior-Chamber Phakic Intraocular Lens Implantation in Patients over 40 Years of Age

Posterior-Chamber Phakic Intraocular Lens Implantation in Patients over 40 Years of Age

Four-year observation of the changes in corneal endothelium cell density and correlated factors after Implantable Collamer Lens V4c implantation

New Technologies in Clinical Trials in Corneal Diseases and Limbal Stem Cell Deficiency: Review from the European Vision Institute Special Interest Focus Group Meeting

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