Anterior segment morphology after laser iridotomy in primary angle closure suspects

Mansoori, Tarannum; Balakrishna, Nagalla

doi:10.1111/cxo.12631

Cited by 8 publications

(5 citation statements)

References 17 publications

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“…In this study, 100 patients with PACS were observed. It was found that the anterior chamber angle was widened, the ACD was deepened, the IC was decreased and the distance between the iris and the ciliary body was significantly shortened after LPI in a Guangzhou population with PACS, which is consistent with previous research results ( 14 – 17 ). The angle opening distance was related to the baseline ACD, IT750, AOD750, and LV before LPI.…”

Section: Discussionsupporting

confidence: 91%

Predictive Equation for Angle Opening Distance at 750 μm After Laser Peripheral Iridotomy in Primary Angle Closure Suspects

et al. 2021

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Aim: The aim of this study was to investigate the changes in anterior segment parameters as assessed by ultrasound biomicroscopy (UBM) after laser peripheral iridotomy (LPI) and to propose a prediction equation for the width of the angle after LPI.Design: This was a prospective study.Participants: The participants included 100 subjects with primary angle closure suspect (PACS).Methods: Anterior segment UBM parameters were measured, whereas AOD750 was chosen to indicate the width of the angle associated with gonioscopic angle closure, as found in a prior study.Main Outcome Measures: Angle parameters, iris parameters, anterior chamber parameters and ciliary body parameters.Results: All angle parameters increased after LPI, including the mean angle opening distance at 750 μm (AOD750), mean angle opening distance at 500 μm from the scleral spur (AOD500), mean angle opening distance at 750 μm from the scleral spur (AOD750), and mean angle recess area at 750 μm from the scleral spur (ARA750). Among iris parameters and ciliary body parameters, the iris thickness at 2,000 μm (IT2000), iris curvature (IC), and trabecular-ciliary process distance (ICPD) were reduced after LPI. The final equation consisted of four parameters: anterior chamber depth (ACD), iris thickness at 750 μm from the scleral spur (IT750), AOD750, and lens vault (LV). This equation explained 42.7% of the variability in the angle opening indicator AOD750 after LPI, whereas in the plateau iris configuration subgroup, the accuracy of the prediction equation reached the highest a maximum of 68.6%.Conclusions: There was an increase in angle opening and iris flattening after LPI. An equation involving four angle parameters was constructed, this equation which could explained 42.7% of the variability in the angle opening indicator AOD750 after LPI whereas in the plateau iris configuration subgroup, the accuracy of the prediction equation reached a maximum of 68.6%.

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Section: Discussionsupporting

confidence: 91%

Predictive Equation for Angle Opening Distance at 750 μm After Laser Peripheral Iridotomy in Primary Angle Closure Suspects

et al. 2021

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“…Unlike our study, they also included patients with primary angle closure (PAC), PAC glaucoma, acute angle closure glaucoma and iris plateau con guration. However, other two studies involving a similar patient group as our study found no signi cant change in ACD after LPI [7,8]. We thought that the discrepancy in results was related to the different methodology of these studies.…”

Section: Discussioncontrasting

confidence: 63%

Short-term changes detected by corneal topography and optical coherence tomography after prophylactic laser iridotomy in primary angle closure suspect

et al. 2023

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Purpose: To evaluate early changes in anterior segment parameters by Scheimp ug-Placido disc topography system and changes in retinal layers by optical coherence tomography in primary angleclosure suspects after laser peripheral iridotomy Methods: One eye of 26 patients with primary angle closure suspect and of 20 healthy subjects were included in this retrospective cross-sectional study. Anterior chamber depth/volume, iridocorneal angle and central corneal thickness were obtained by Scheimp ug-Placido disc topography system. Retinal thickness, retinal nerve ber layer thickness and ganglion cell-inner plexiform layer thickness were acquired by optical coherence tomography. All the tests were repeated 1 week and 1 month after laser peripheral iridotomy.Results: The mean ages of the patients and healthy controls were 64.8±10.7 years and 64.5 ± 3.9 years, respectively (p=0.990). Anterior chamber depth/volume and iricorneal angle value were lower in the PACS group (p<0.001, for all). Anterior chamber volume and iridocorneal angle increased signi cantly after laser peripheral iridotomy (p=0.004, for both). While foveal thickness decreased signi cantly after laser peripheral iridotomy (p=0.027), retinal nerve ber layer thickness increased in superior and temporal quadrants (p=0.038 and p=0.016, respectively). Conclusion: Our results suggest that LPI in patients with PACS provides improved retinal thickness and RNFL thickness, as well as anterior chamber parameters.

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“…[ 8 ] measured the anterior segment parameters following LPI in PACD using Pentacam (Oculus Pentacam, Wetzlar, Germany) and compared it to measurements using AS-OCT (Carl Zeiss Meditec) and demonstrated a significant change in ICA, which was comparable to both the imaging modalities. Mansoori and Balakrishna[ 13 ] demonstrated a similar change using a Scheimpflug-based device with good reproducibility.…”

Section: Discussionmentioning

confidence: 92%

“…Our study did not show a significant difference in HVID, HACD, CCT, and CV after LPI in PACD patients, which is expected and similar to previous reports. [ 13 , 19 ]…”

Section: Discussionmentioning

confidence: 99%

Evaluation of changes in anterior segment morphology using Sirius Scheimpflug-Placido disk topographer following laser peripheral iridotomy in primary angle-closure disease

Stephen

Kaliaperumal

Behera

2023

Indian Journal of Ophthalmology

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Purpose: To assess the morphological changes in the anterior segment following laser peripheral iridotomy (LPI) in primary angle-closure disease (PACD) using Sirius Scheimpflug-Placido disk corneal topographer. Methods: This was a prospective observational study. A total of 52 eyes of 27 patients with PACD who underwent LPI were analyzed for iridocorneal angle (ICA), anterior chamber depth (ACD), anterior chamber volume (ACV), horizontal visible iris diameter (HVID), corneal volume (CV), central corneal thickness (CCT), and horizontal anterior chamber diameter (HACD) 1 week following LPI, using Sirius Scheimpflug-Placido disk corneal topographer. Data analysis was done using Statistical Package for the Social Sciences (SPSS) software version 19.0, and paired t -test was used to assess the statistical significance. Results: Laser peripheral iridotomy was performed in 43 eyes with primary angle-closure suspect (PACS), six eyes with primary angle closure (PAC), and three eyes with primary angle-closure glaucoma (PACG). The analysis of the data showed statistically significant changes in anterior segment parameters of ICA, ACD, and ACV. Post-laser increase in ICA from 34.13° ± 2.64° to 34.75° ± 2.84° ( P < 0.041), mean ACD increase from 2.21 ± 0.25 to 2.35 ± 0.27 mm ( P = 0.01), and mean ACV increase from 98.19 ± 12.13 to 104.15 ± 11.16 mm 3 ( P = 0.001) were noted. Conclusion: Significantly quantifiable short-term changes in the anterior chamber parameters of ICA, ACD, and AC volume were seen after LPI in patients with PACD on Sirius Scheimpflug-Placido disc corneal topographer.

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Anterior segment morphology after laser iridotomy in primary angle closure suspects

Cited by 8 publications

References 17 publications

Predictive Equation for Angle Opening Distance at 750 μm After Laser Peripheral Iridotomy in Primary Angle Closure Suspects

Predictive Equation for Angle Opening Distance at 750 μm After Laser Peripheral Iridotomy in Primary Angle Closure Suspects

Short-term changes detected by corneal topography and optical coherence tomography after prophylactic laser iridotomy in primary angle closure suspect

Evaluation of changes in anterior segment morphology using Sirius Scheimpflug-Placido disk topographer following laser peripheral iridotomy in primary angle-closure disease

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