An anterior sacral meningocele (ASM) may be diagnosed by combining different imaging modalities. This case report describes multimodality imaging findings including radiography (X-ray), ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI) in a 52-year-old woman with right sacral neuropathic pain and a pelvic mass. The consultant gynecologist performed a pelvic ultrasound, and she was referred to the radiology department as suspected ovarian tumor. The X-rays showed opacification of the pelvic cavity with enlargement of the first two sacral foramina. US showed an anechoic, multilobulated pelvic mass with posterior acoustic enhancement which was avascular on color Doppler US; the origin of the pelvic mass was undetermined. CT scan of the abdomen and pelvis with contrast showed a large cystic pelvic tumor with associated mass effect, displacement of adjacent organs, extension through the remodeled and enlarged sacral foramina in the first two sacral vertebrae, and continuity with the thecal sac through a wide neck, consistent with an ASM. MRI confirmed the findings, and ASM was diagnosed. This case is the first report of an ASM in Mexico and is presented for educational purposes to highlight the findings of ASM in four imaging modalities: X-ray, US, CT, and MRI.