Anterior mitral annulus caseoma: as benign as posterior counterparts?

Mazzucco, Alessandro; Abbasciano, Riccardo; Brognoli, Gabriele; Fanti, Diego; Gottin, Leonardo; Faggian, Giuseppe

doi:10.1016/j.carpath.2015.10.002

Cited by 4 publications

(2 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This is commonly seen in elderly women and patients with calcium metabolism abnormalities or renal failure, suggesting that a high turnover of calcium contributes to the development of MAC 11 . The aetiology of caseous necrosis in CCMA is still debated, but similarities to atheromas seen in atherosclerotic cardiovascular disease have been suggested 8 , 11 . Findings such as severe calcific atherosclerosis of the coronary arteries and hypertension, both present in our case, are commonly described in patients with CCMA, further supporting this theory.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Caseous calcification of the mitral annulus: case report and brief review

Curl

Riemer

2018

European Heart Journal - Case Reports

View full text Add to dashboard Cite

BackgroundCaseous calcification of the mitral annulus (CCMA) is a very rare variant of mitral annular calcification, which is typically asymptomatic but can manifest as a cardiac tumour, abscess, or in the form of mitral valve dysfunction.Case summaryWe present a patient who developed shortness of breath and was initially thought to have an intracardiac tumour, but ultimately was recognized as massive calcification of the mitral valve by computed tomography angiogram. This finding was unfortunately made only shortly before the patient’s clinical deterioration, and the specific diagnosis of CCMA was made on post-mortem findings, precluding any directed treatment for this entity.DiscussionCaseous calcification of the mitral annulus can lead to significant pathology, including mitral regurgitation, stenosis, or systemic embolization of caseous material. Due to its relative scarcity and tendency to be asymptomatic, a diagnosis of CCMA is often difficult to make or easily overlooked. Early recognition and appropriate treatment is crucial for avoiding these potential complications.

show abstract

Section: Discussionmentioning

confidence: 99%

“…This condition can also manifest with conduction abnormalities or sometimes with systemic embolization of caseous material 7 . Caseous calcification of the mitral annulus is nearly always described as involving the posterior portion of the mitral annulus, but uncommonly involves the anterior portion alone or the entire annulus 8 …”

Section: Introductionmentioning

confidence: 99%

Caseous calcification of the mitral annulus: case report and brief review

Curl

Riemer

2018

European Heart Journal - Case Reports

View full text Add to dashboard Cite

show abstract

Mitral Annular Calcification: Association with Atherosclerosis and Clinical Implications

Cavalcanti

Perazzo

Neto

et al. 2020

Curr Atheroscler Rep

View full text Add to dashboard Cite

Asymptomatic Caseous Calcification of the Mitral Annulus in a 66-Year-Old Woman with 3-Year Imaging Follow-Up

et al. 2022

View full text Add to dashboard Cite

Patient: Female, 66-year-old Final Diagnosis: Caseous calcification of the mitral annulus Symptoms: Asymptomatic Medication:— Clinical Procedure: — Specialty: Cardiology Objective: Rare disease Background: Caseous calcification of the mitral annulus (CCMA) is an uncommon form of mitral annular calcification and can be misdiagnosed as heart abscess, neoplasm, or other lesions occupying the atrioventricular groove. Data regarding imaging follow-up of patients with CCMA are limited. This report presents a case of CCMA with a 3-year imaging follow-up. Case Report: A 66-year-old asymptomatic woman was referred to our cardiology department for further evaluation of a rapidly expanding intracardiac mass observed using transthoracic echocardiography (TTE) in an outpatient setting. A neoplasm was suspected. Echocardiographic examination was normal 5 years ago, and 2 years later, TTE revealed an echodense structure (10×10 mm) occupying the atrioventricular groove. Three years later, TTE revealed an increase in the size of the lesion (21×18 mm) and a mild acoustic shadow. Cardiac magnetic resonance imaging revealed a pathological mass (20×20×37 mm) in the posterior portion of the mitral annulus that extended into the left ventricle. Using computed tomography, a round mass (20×19×39 mm) with a demarcated area of calcification was revealed in the posterior portion of the mitral annulus. Thus, the intracardiac mass was diagnosed as CCMA. Although there was a considerable increase in lesion size (doubling of lesion size within 3 years), normal intracardiac flow and asymptomatic course of the disease remained. Therefore, this patient underwent conservative management with imaging follow-up. Conclusions: In cases of atypical presentation of CCMA, multimodal imaging may provide an accurate diagnosis and important information regarding the course of the disease.

show abstract

Anterior mitral annulus caseoma: as benign as posterior counterparts?

Cited by 4 publications

References 8 publications

Caseous calcification of the mitral annulus: case report and brief review

Caseous calcification of the mitral annulus: case report and brief review

Mitral Annular Calcification: Association with Atherosclerosis and Clinical Implications

Asymptomatic Caseous Calcification of the Mitral Annulus in a 66-Year-Old Woman with 3-Year Imaging Follow-Up

Contact Info

Product

Resources

About