Anterior maxillary metastasis of gastric adenocarcinoma: A rare case

Abstract

Metastatic tumors of the oral cavity are rare, representing about 1% of oral tumors. Seventy percent of all tumors metastatic to the oral and maxillofacial region are adenocarcinomas, most commonly originating from the breast, kidney and lung. Carcinoma of stomach is generally described as one of the “captains of men of death”. Usual sites of metastasis from gastric adenocarcinoma are direct invasion of adjacent organs, peritoneal dissemination, lymphatic metastasis and hematogenous spread. A primary carcinoma of the stomach may rarely metastasize to the oral cavity, it is important to bear this possibility in mind because such conditions may mimic a benign disease. This article describes a case of metastasis of gastric adenocarcinoma to the maxilla in a 50-year-old male.

Metastatic Tumours to the Oral Cavity: Report of Three Cases

“…A metastatic lesion in the oral soft tissue is more easily recognized. Gingival metastases usually appear as a polypoid or exophytic mass, highly vascularized and hemorrhagic [ 4 , 6 , 7 , 10 , 17 , 19-28 ].…”

“…Aforementioned signs and symptoms may lead to a misdiagnosis. The differential diagnosis includes hemangioma, pyogenic granuloma, giant-cell granuloma, peripheral fibroma, adenoid squamous cell carcinoma, polymorphous low-grade adenocarcinoma that affects the minor salivary glands of the mouth [ 2 , 4 , 9 , 11 , 12 , 14 , 15 , 19 , 21 , 22 , 27 , 29-41 ]. In our second case, the gingival lesion was first diagnosed as an inflammatory lesion and treated with tooth extraction and antibiotics, but the patient’s symptoms deteriorated despite the treatment.…”

Gastric Carcinoma Metastases to the Anterior Maxilla: A Rare Case Report

“…Malignant tumors of the oral region constitute about 5% of all malignant tumors, of which 1% are metastatic (1,2). In some cases, oral metastatic tumors are the first indication of an undiagnosed primary tumor (3).…”

“…Gastric carcinoma metastasizes of the oral cavity are extremely rare (3). Patients with metastasis in the oral cavity usually develop metastases in other regions of the body (2).…”

“…In the early period, gastric carcinoma can present with mild or no symptoms. Therefore, the tumor is usually detected in late stages (3). The prognoses of these patients are very poor (4,5).…”