Anterior Cruciate Ligament Injuries: Operative and Rehabilitative Options

Gotlin, Robert S.; Huie, Gordon

doi:10.1016/s1047-9651(18)30107-4

Cited by 23 publications

(7 citation statements)

References 47 publications

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“…Many questions are as yet unanswered, however, and, as such, this lack of information may promote the inadvertent use of unsafe exercises or movements. At the same time, clinicians are faced daily with individuals recovering from ACL trauma, an injury that frequently afflicts and disables those enjoying a demanding active lifestyle (Gotlin and Huie 2000). What should they as professionals be administering as an efficacious ACL protocol?…”

Section: Resultsmentioning

confidence: 99%

Exercises Following Anterior Cruciate Ligament Reconstructive Surgery: Biomechanical Considerations and Efficacy of Current Approaches

Grodski

Marks

2008

Research in Sports Medicine

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To enable a safe, effective return to daily functional activities and to prevent premature knee joint osteoarthritis, adults undergoing anterior cruciate ligament (ACL) surgery require carefully designed and appropriate rehabilitation strategies. In this article we critically examine the contemporary body of literature concerning the application and outcomes of various knee exercise rehabilitation protocols described in the literature in the context of the surgically repaired ACL injured knee. These data were obtained from the MEDLINE (1991-2007), CINAHL (1982-2007), and SPORTS DISCUS (1975-2007) databases, using the terms anterior cruciate ligament, exercise, and ligament, showed that two lines of research currently dominate this topic: (1) the role of open versus closed chain exercises approaches; (2) the impact of these exercises on knee stability and function post-ACL surgery. In light of the small number of studies and their methodological limitations, however, more research clearly is recommended to establish if closed-chain kinetic exercises are conclusively more efficacious than open-chain exercise for this condition, as predicted by the present literature base.

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Section: Resultsmentioning

confidence: 99%

Exercises Following Anterior Cruciate Ligament Reconstructive Surgery: Biomechanical Considerations and Efficacy of Current Approaches

Grodski

Marks

2008

Research in Sports Medicine

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“…The mechanical properties of the ACL, crucial to its function, are complex, showing variable tension among fibre bundles and variable modulus as a function of load level and viscoelastic effects (creep, relaxation and strain‐rate sensitivity). The ACL is the most frequently injured knee ligament, especially in athletes, accounting for 200 000 injuries and approximately 100 000 reconstruction procedures reported annually in the USA alone (Gotlin and Huie, ; Majewski et al ., ). Most patients are 20–29 years of age but gender incidence is still a subject of debate (Majewski et al ., ).…”

Section: Tendon and Ligament Injuriesmentioning

confidence: 99%

Engineering tendon and ligament tissues: present developments towards successful clinical products

Rodrigues

Reis

Gomes

2012

J Tissue Eng Regen Med

143

213

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Musculoskeletal diseases are one of the leading causes of disability worldwide. Among them, tendon and ligament injuries represent an important aspect to consider in both athletes and active working people. Tendon and ligament damage is an important cause of joint instability, and progresses into early onset of osteoarthritis, pain, disability and eventually the need for joint replacement surgery. The social and economical burden associated with these medical conditions presents a compelling argument for greater understanding and expanding research on this issue. The particular physiology of tendons and ligaments (avascular, hypocellular and overall structural mechanical features) makes it difficult for currently available treatments to reach a complete and long-term functional repair of the damaged tissue, especially when complete tear occurs. Despite the effort, the treatment modalities for tendon and ligament are suboptimal, which have led to the development of alternative therapies, such as the delivery of growth factors, development of engineered scaffolds or the application of stem cells, which have been approached in this review.

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“…The ACL is also the most frequently injured knee ligament 44 , with 200,000 injuries and approximately 100,000 reconstruction procedures reported annually in the United States alone 45,46 . The long-term performance of ACL grafts depends the structural and material properties of the graft, initial graft tension 47–51 , the intra-articular position of the graft 52,53 , and graft fixation 9,10 .…”

Section: Design Considerations In Acl-bone Interface Tissue Enginmentioning

confidence: 99%

Orthopedic Interface Tissue Engineering for the Biological Fixation of Soft Tissue Grafts

Moffat¹,

Wang²,

Rodeo³

et al. 2009

Clinics in Sports Medicine

100

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Interface tissue engineering is a promising new strategy aimed at the regeneration of tissue interfaces and ultimately enabling the biological fixation of soft tissue grafts utilized in orthopaedic repair and sports medicine. Many ligaments and tendons with direct insertions into subchondral bone exhibit a complex enthesis consisting of several distinct yet continuous regions of soft tissue, noncalcified fibrocartilage, calcified fibrocartilage and bone. Regeneration of this multi-tissue interface will be critical for functional graft integration and improving long term clinical outcome. This review will highlight current knowledge of the structure-function relationship at the interface, the mechanism of interface regeneration, and the strategic biomimicry implemented in stratified scaffold design for interface tissue engineering and multi-tissue regeneration. Potential challenges and future directions in this emerging field will also be discussed. It is anticipated that interface tissue engineering will lead to the design of a new generation of integrative fixation devices for soft tissue repair, and it will be instrumental for the development of integrated musculoskeletal tissue systems with biomimetic complexity and functionality.

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Anterior Cruciate Ligament Injuries: Operative and Rehabilitative Options

Cited by 23 publications

References 47 publications

Exercises Following Anterior Cruciate Ligament Reconstructive Surgery: Biomechanical Considerations and Efficacy of Current Approaches

Exercises Following Anterior Cruciate Ligament Reconstructive Surgery: Biomechanical Considerations and Efficacy of Current Approaches

Engineering tendon and ligament tissues: present developments towards successful clinical products

Orthopedic Interface Tissue Engineering for the Biological Fixation of Soft Tissue Grafts

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