Anterior chamber contamination during cataract surgery with intraocular lens implantation

Mistlberger, Andrea; Ruckhofer, Josef; Raithel, Erich; Müller, Manfred J.; Alzner, E.; Egger, S.; Grabner, Günther

doi:10.1016/s0886-3350(97)80081-8

Cited by 108 publications

(56 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In fact, the current culture media for isolating conjunctival bacteria described in Chapter 1 21 is different from that in the Khorazo et al studies 3 mentioned in Chapter 24 of the same volume, in the same book 21 (revised 10 years before). In more recent studies [25][26][27][28][29][30][31][32][33][34][35][36][37][38] most samples of patients undergoing cataract surgery have a small size and the frequency of the isolated bacteria varies a lot between them due to different factors 18 (the isolating culture media used, the exclusion criteria used to select the patients and the geographical area where they lived). Among these factors the climatic conditions in Madrid have been statistically associated with the conjunctival bacteria frequency of our patients undergoing cataract surgery.…”

Section: Discussionmentioning

confidence: 99%

Influence of age on conjunctival bacteria of patients undergoing cataract surgery

Rubio

2005

Eye

View full text Add to dashboard Cite

Aim To ascertain the effect of elderly in the conjunctival bacteria frequency of patients undergoing cataract extraction. Methods A retrospective case series study of 4432 consecutive patients who underwent cataract surgery, without excluding any of them for having pre-existing diseases. Their preoperative conjunctival culture were performed over a 3-year period (1994)(1995)(1996). Bacteria were grouped in nine categories and patients were divided into seven groups, according to age; comparisons between groups were made by means of the v 2 test, and the Mantel-Haenszel test to analyse age as a confounder, using SPSS program, version 12. Results Patients aged over 74 years accounted for 41.4%; women predominated among this group (61.4%), but not in the patients younger than 75 (47.7%); In the whole sample women accounted for 53.4%. Patients aged 75-96 years had a greater frequency of: Corynebacteria, Staphylococcus aureus, Streptococcus sp. (except Streptococcus pneumoniae), Gram-negative cocci and Gramnegative rods (except Haemophilus sp.) and 'other bacteria' categories than those aged 3-74 years. Different bacteria frequency in both sexes produced a confounding effect in the comparison between age-groups. Men had more Staphylococci coagulase (-), S. pneumoniae and Gram-negative rods than women. Conclusions Elderly patients awaiting cataract surgery had more conjunctival bacteria than those younger than 75 years, except Staphylococcus coagulase negative, S. pneumoniae and Haemophilus sp. At any age, men had more bacteria than women. These increments of frequencies could increase the risk of intraocular surgery contamination.

show abstract

Section: Discussionmentioning

confidence: 99%

Influence of age on conjunctival bacteria of patients undergoing cataract surgery

Rubio

2005

Eye

View full text Add to dashboard Cite

show abstract

“…Subconjunctival cefuroxime achieves therapeutic levels in the anterior chamber within 12-24 min of administration and maintains clinically significant levels for up to 12 h. 17,18 Postoperative therapeutic antibiotic levels within the anterior chamber will help to counteract the potential bacterial load in the eye as bacteria are present in the anterior chamber at the end of cataract surgery in 13-43% of patients. [19][20][21] There are some limitations to this study. Case ascertainment was questionnaire-based and dependent on voluntary reporting by ophthalmologists throughout the UK.…”

Section: Discussionmentioning

confidence: 98%

Presumed infectious endophthalmitis following cataract surgery in the UK: a case–control study of risk factors

Kamalarajah

Ling

Silvestri

et al. 2006

Eye

View full text Add to dashboard Cite

Aims To study risk factors for presumed infectious endophthalmitis complicating cataract surgery in the United Kingdom. Methods Two hundred and fourteen clinically diagnosed patients with presumed infectious endophthalmitis were compared with 445 control patients throughout the United Kingdom in a prospective case-control study. The cases were identified through the British Ophthalmological Surveillance Unit reporting card system. Control patients undergoing cataract surgery from 13 'control centres' throughout the United Kingdom were selected randomly. Risk factors were identified by univariate and multivariate logistic regression analyses. Pertinent variables relating to the cataract extraction procedure, antimicrobial prophylaxis, ophthalmic and medical history were analysed with regard to postoperative infection. Results Statistically significant risk factors in the multivariate model included inpatient cataract surgery (P ¼ 0.001), surgery in dedicated eye theatres (Po0.001), consultant grade surgeon (compared to registrar) (P ¼ 0.001), posterior capsule tear during cataract surgery (P ¼ 0.001). The use of face masks by the scrub nurse and surgeon during cataract surgery (Po0.001) and the administration of subconjunctival antibiotics at the end of surgery (Po0.001) were protective against postoperative infection. Conclusions In order to minimise the risk of postoperative endophthalmitis we would recommend the wearing of face masks by the surgeon and scrub nurse during cataract surgery and subconjunctival antibiotics at the end of surgery.

show abstract

“…The seed stock of the Piry virus, strain BeAn 41191 (LD 50 =10 8,5 ), was obtained from the brain macerates of an infected mice.…”

Section: Methodsmentioning

confidence: 99%

“…This increase has occurred si contaminates the aspiration fluid (13) . Contamination of the aspiration fluid may seem normal to a certain extent because it has been shown that during and at the conclusion of intraocular operations, bacteria are present on the conjunctiva and in the anterior chamber (4,5) . It has been suspected that reflux from the internal tubing repre sented a potential source of endophthalmitis, but outflow lines have not been investigated.…”

Section: Introductionmentioning

confidence: 99%

Viral contamination during sequential phacoemulsification surgeries in an experimental model

Coelho¹,

Garcia²,

Paula³

et al. 2012

Arq. Bras. Oftalmol.

View full text Add to dashboard Cite

Purpose: To determine the incidence of Piry virus contamination among surgical instruments used with disposable accessories for phacoemulsification during se quential surgeries. Methods: An experimental model was created with 4 pigs' eyes that were conta minated with Piry virus and 4 pigs' eyes that were not contaminated. Phacoemul sification was performed on the eyes, alternating between the contaminated and noncontaminated eyes. From one surgery to another, the operating fields, gloves, scalpel, tweezers, needles, syringes, tips and bag collector from the phacoemulsi fi cation machine were exchanged; only the hand piece and the irrigation and aspira tion systems were maintained. Results: In the collector bag, three samples from the contaminated eyes (3/4) were positive, and two samples from the noncontaminated (2/4) eyes were also positive; at the tip, one sample from the contaminated eyes (1/4) and two samples of the non contaminated eyes (2/4) yielded positive results. In the irrigation system, one sample from a noncontaminated eye (1/4) was positive, and in the aspiration system, two samples from contaminated eyes (2/4) and two samples from noncontaminated eyes (2/4) were positive. In the gloves, the samples were positive in two samples from the noncontaminated eyes (2/4) and in two samples from the contaminated eyes (2/4). In the scalpel samples, three contaminated eyes (3/4) and none of the noncontaminated eyes (0/4) were positive; finally, two samples from the anterior chambers of the noncontaminated eyes gathered after surgery were positive. Conclusions: In two noncontaminated eyes, the presence of genetic material was detected after phacoemulsification surgery, demonstrating that the transmission of the genetic material of the Piry virus occurred at some point during the surgery on these noncontaminated eyes when the hand piece and irrigation and aspiration systems were reused between surgeries.

show abstract

Anterior chamber contamination during cataract surgery with intraocular lens implantation

Cited by 108 publications

References 19 publications

Influence of age on conjunctival bacteria of patients undergoing cataract surgery

Influence of age on conjunctival bacteria of patients undergoing cataract surgery

Presumed infectious endophthalmitis following cataract surgery in the UK: a case–control study of risk factors

Viral contamination during sequential phacoemulsification surgeries in an experimental model

Contact Info

Product

Resources

About