Anterior and posterior capsular opacification with the Tecnis ZCB00 and AcrySof SA60AT IOLs: a randomised intraindividual comparison

Abstract

Both IOLs had a similar low rate of PCO 1 year after surgery. However, there seems to be a difference in the anterior capsule behaviour between both IOL models.

Intraindividual comparative analysis of capsule opacification after implantation of 2 single-piece hydrophobic acrylic intraocular lenses models: Three-year follow-up

“…Of the original 160 eyes (80 patients) enrolled, 12 (6) were excluded because of a large and nonoverlapping CCC and 48 (24) were lost to follow-up or were excluded because of insufficient retroillumination image quality. All surgeries were uneventful.…”

“…Eyes with an IOL with an interrupted square optic edge had statistically significantly higher percentages of ACO and higher ACO scores than eyes with a continuous square optic edge IOL; this is similar to the 1-year results in a previous study evaluating the same 2 IOL models. 6 Because IOLs were implanted in fellow eyes of the same patient, we assume that factors inherent in the individual patient can be disregarded (intraindividual comparison). The differences in IOL surface properties and design might explain this finding.…”

“…1-3 A comparative study by Nixon and Woodcock 5 evaluating the PCO rate 2 years postoperatively found that eyes with an IOL with a continuous 360-degree sharp square edge (Tecnis AAB00, Abbott Medical Optics, Inc.) had significantly less PCO than eyes with an IOL with interruption of the square edge at the optic-haptic junction (Acrysof SA60AT or SN60AT, Alcon Surgical, Inc.). Another study 6 confirmed the presence of significant differences in anterior capsule behavior between 2 IOLs with sharp square optic edges, 1 with a continuous edge and the other with an interrupted edge.…”

Posterior Capsular Changes and Its Association With Posterior Chamber Intraocular Lens Surface Changes After Extracapsular Cataract Extraction

“…6 The intraocular lenses have a role in preventing and promoting posterior capsular changes. 7,8 Lens epithelial cells (LECs) transdifferentiate to myofibroblastic cells, producing collagen fibres around the anterior capsulotomy margins. 1 These fibres cause the anterior capsulotomy margin to adhere to the posterior capsule to form a closed space in which LECs differentiate into lens fibre cells.…”

Are lens implant modifications the best way to prevent posterior capsule opacification?

“…Kahraman et al 26 recently showed that the square edge design of the two modern IOLs described does not show a significant difference for PCO rates—there is a slight tendency for the AcrySof IOL to develop PCO, anterior capsule opacification, and capsular phimosis faster. A limitation of their study was the short follow-up time of only 12 months, as the usual PCO development for modern IOLs was evaluated in other studies over a period of at least 11–36 months 6 7 9–11 27.…”