Antepartum and postpartum exposure to maternal depression: different effects on different adolescent outcomes

Hay, Dale F.; Pawlby, Susan; Waters, Cerith S.; Sharp, Deborah

doi:10.1111/j.1469-7610.2008.01959.x

Cited by 213 publications

(187 citation statements)

References 33 publications

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“…It may be that a significant portion of women with postpartum-onset depression remain depressed beyond the child's first year, which in our study would have lead them to be assigned to a group with persistent symptoms. Nevertheless, with a notable exception [29] , prior studies indicate that exposure to maternal depression in the period up to one year after birth does not exert an independent influence on the child's cognitive function [7; 10] .…”

Section: Patterns Of Association Between Maternal Depression and Chilmentioning

confidence: 99%

Persistent maternal depressive symptoms trajectories influence children's IQ: The EDEN mother-child cohort

et al. 2016

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for The EDEN Mother–Child Cohort Study GroupInternational audienceBackground: This study assessed the association between timing and course of maternal depression from pregnancy onwards and children's cognitive development at ages 5 to 6. Potential interaction effects with child sex and family socioeconomic status were explored.Methods: One thousand thirty-nine mother–child pairs from the French EDEN mother–child birth cohort were followed from 24 to 28 weeks of pregnancy onwards. Based on Center for Epidemiological Studies Depression (CES-D) and Edinburgh Postnatal Depression Scale (EPDS) scores assessed at six timepoints, longitudinal maternal depressive symptom trajectories were calculated with a group-based semiparametric method. Children's cognitive function was assessed at ages 5 to 6 by trained interviewers with the Wechsler Preschool and Primary Scale of Intelligence Third Edition (WPPSI-III), resulting in three composite scores: Verbal IQ (VIQ), Performance IQ (PIQ), and Full-Scale IQ (FSIQ).Results: Five trajectories of maternal symptoms of depression could be distinguished: no symptoms, persistent intermediate-level depressive symptoms, persistent high depressive symptoms, high symptoms in pregnancy only, and high symptoms in the child's preschool period only. Multiple linear regression analyses showed that, compared to children of mothers who were never depressed, children of mothers with persistent high levels of depressive symptoms had reduced VIQ, PIQ, and FSIQ scores. This association was moderated by the child's sex, boys appearing especially vulnerable in case of persistent maternal depression.Conclusions: Chronicity of maternal depression predicts children's cognitive development at school entry age, particularly in boys. As maternal mental health is an early modifiable influence on child development, addressing the treatment needs of depressed mothers may help reduce the associated burden on the next generation

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Section: Patterns Of Association Between Maternal Depression and Chilmentioning

confidence: 99%

Persistent maternal depressive symptoms trajectories influence children's IQ: The EDEN mother-child cohort

et al. 2016

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“…19 For example, 10-year-old children exposed to maternal PPD symptoms since birth have larger left and right amygdala and a heightened cortisol response to stress, 20 and other long-term associations have also been observed between maternal PPD and cognitive outcomes including IQ in adolescents. 21 …”

Section: Postpartum Depressionmentioning

confidence: 99%

Emerging Risk Factors for Postpartum Depression: Serotonin Transporter Genotype and Omega-3 Fatty Acid Status

2012

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Objective: Depression is a leading cause of disability and hospitalization. Women are at the highest risk of depression during their childbearing years, and the birth of a child may precipitate a depressive episode in vulnerable women. Postpartum depression (PPD) is associated with diminished maternal somatic health as well as health and developmental problems in their offspring. This review focuses on 2 PPD risk factors of emerging interest: serotonin transporter (5-HTT) genotype and omega-3 polyunsaturated fatty acid (n-3 PUFA) status. Method:The MEDLINE, PubMed, and Web of Science databases were searched using the key words postpartum depression, nutrition, omega-3 fatty acids, and serotonin transporter gene. Studies were also located by reviewing the reference lists of selected articles.Results: Seventy-five articles were identified as relevant to this review. Three carefully conducted studies reported associations between the 5-HTT genotype and PPD. As well, there is accumulating evidence that n-3 PUFA intake is associated with risk of PPD. Preliminary evidence suggests that there could be an interaction between these 2 emerging risk factors. However, further studies are required to confirm such an interaction and to elucidate the underlying mechanisms. Conclusions:Evidence to date supports a research agenda clarifying the associations between n-3 PUFAs, the 5-HTT genotype, and PPD. This is of particular interest owing to the high prevalence of poor n-3 PUFA intake among women of childbearing age and the consequent potential for alternative preventive measures and treatments for PPD. W W WObjectif : La dépression est une cause principale d'incapacité et d'hospitalisation. Les femmes sont les plus à risque de dépression durant leur période d'enfantement, et la naissance d'un enfant peut précipiter un épisode dépressif chez les femmes vulnérables. La dépression du postpartum (DPP) est associée avec la santé somatique maternelle diminuée ainsi qu'avec des problèmes de santé et de développement chez leur enfant. Cette étude se penche sur 2 facteurs de risque de DPP qui suscitent un nouvel intérêt : le génotype du transporteur (5-HTT) de la sérotonine et l'état des acides gras (n-3 PUFA) omega-3 polyinsaturés.Méthode : Une recherche a été effectuée dans les bases de données MEDLINE, PubMed, et Web of Science à l'aide des mots clés dépression du postpartum, nutrition, acides gras omega-3, et gène du transporteur de la sérotonine. Des études ont aussi été trouvées en examinant la bibliographie des articles relevés.Résultats : Soixante-quinze articles ont été jugés pertinents pour cette étude. Trois études menées rigoureusement rapportaient des associations entre le génotype du 5-HTT et la DPP. De même, les preuves s'accumulent à l'effet que l'ingestion de n-3 PUFA soit associée à un risque de DPP. Les données probantes préliminaires suggèrent qu'il pourrait y avoir une interaction entre les 2 nouveaux facteurs de risque. Cependant, il faut d'autres études pour confirmer cette interaction et pour clarifier les méca...

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“…For example, mothers with depression may lack normal verbal and nonverbal (including facial) communication, be unresponsive or insensitive to their infant's needs and communication, be deficient in touching their child, and engage in activities inappropriate for the child's develop mental stage or temperament (Punamäki 2006). Maternal postpartum (but not antenatal) depression has also been associated with lower adolescent IQ, especially in males (Hays 2008).…”

Section: Child Behaviour and Psychopathologymentioning

confidence: 99%

Making decisions in the management of perinatal depression and anxiety

Wand

2014

Adv. psychiatr. treat

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SummaryThe care of women with anxiety and depressive disorders in the perinatal period is complex. The literature in this field is vast and may be difficult for busy clinicians to keep abreast of. The first part of this article provides an overview of the potential risks and benefits of treatment options, including no treatment, at various stages in the perinatal period. The second part explores the frameworks which may assist clinicians in decision-making with their pregnant patients, including risk-benefit analysis, ethical considerations, evaluating capacity, and mental health legislation. The common pitfalls and limitations of these approaches are examined to guide good practice.LEARNING OBJECTIVES•Understand the potential risks and benefits of treating, or not treating, maternal mental illness at various stages in the perinatal period.•Understand the limitations of the literature in this field.•Be able to use different frameworks for deciding with patients about the management of mental illness in the perinatal period.

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Antepartum and postpartum exposure to maternal depression: different effects on different adolescent outcomes

Cited by 213 publications

References 33 publications

Persistent maternal depressive symptoms trajectories influence children's IQ: The EDEN mother-child cohort

Persistent maternal depressive symptoms trajectories influence children's IQ: The EDEN mother-child cohort

Emerging Risk Factors for Postpartum Depression: Serotonin Transporter Genotype and Omega-3 Fatty Acid Status

Making decisions in the management of perinatal depression and anxiety

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