Antenatal Steroid in Preterm Infants with Respiratory Distress Syndrome

Gabr, Heba Elsayed; Fouad, Mariam Adel

doi:10.21608/ejhm.2022.247134

Cited by 2 publications

(1 citation statement)

References 19 publications

(19 reference statements)

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“…27 Additionally, the severity of RDS can impact the length of stay, with more severe cases requiring longer hospitalization. 28 It has been found that preterm infants with severe RDS who require mechanical ventilation have increased cortisol levels, indicating a higher stress level associated with respiratory distress. 29 Therefore, the presence and severity of RDS in preterm infants can contribute to a longer LOS.…”

Section: Discussionmentioning

confidence: 99%

Risk Factors Affecting Length of Stay in Preterm Infants at Wangaya Regional General Hospital, Indonesia

Putri Prashanti,

Kanthi Soraca Widiatmika,

Putu Siska Suryaningsih

et al. 2023

Bioscmed

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Background: Advances in neonatology have led to many preterm infants being saved. Prolonged length of stay (LOS) increases the incidence of neonatal complications and even mortality, placing a significant economic burden on families and strain on healthcare systems. This study aims to determine the factors associated with LOS in preterm infants. Methods: This cross-sectional study involved 60 preterm babies treated at Wangaya Hospital from May 2022 to May 2023. Infants with congenital anomalies, referred from other hospitals and did not receive appropriate treatment were excluded from the study. Data were taken from the electronic medical record after obtaining ethical clearance and then analyzed using descriptive statistics and linear regression in SPSS 25. Statistical significance was considered at 0.05. Results: As many as 46 out of 60 preterm infants were born at moderate to late preterm gestational age. The majority of 81.7% of infants were born with a body weight of 1500-2499 grams. The median number of LOS was 7.5 days (IQR 15). Multivariate analysis of numerical independent variables obtained an equation log [LOS] = 2.902-0.066*gestational age+ 0.022*duration of parenteral nutrition (R2 = 78.1%). Meanwhile, in the categorical independent variables obtained, an equation log [LOS] = 0.398 + 0.223*very preterm + 0.144* RDS + 0.178*NEC + 0.206*prolonged antibiotics administration + 0.278*late enteral feeding + 0.148*abdominal distension + 0.144*vomiting (R2 = 87.4%). Conclusion: Factors influencing LOS of preterm infants are gestational age, duration of parenteral nutrition, the presence of RDS, NEC, vomiting, abdominal distension, late enteral feeding, and prolonged use of antibiotics. It is essential to carry out antenatal care for pregnant women to prevent premature birth.

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Section: Discussionmentioning

confidence: 99%

Risk Factors Affecting Length of Stay in Preterm Infants at Wangaya Regional General Hospital, Indonesia

Putri Prashanti,

Kanthi Soraca Widiatmika,

Putu Siska Suryaningsih

et al. 2023

Bioscmed

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Study of Effect of Antenatal Steroids on Mechanically Ventilated Low Birth Weight Neonates With Respiratory Distress Admitted to Neonatal Intensive Care Unit(nicu)

Goud¹,

Kartik.²,

Adarsh.³

2023

ijsr

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Background: Low birth weight (LBW) is dened as a birth weight of less than 2.5kg as per World Health Organization (WHO)1. Low birth weight (LBW) is a major public health problem in developing countries including India. In India, 30-35% of babies are LBW and more than half of them are full term babies2. Reduction of low birth weight forms an important contribution to the Millennium Development Goal (MDG) for reducing child mortality3. Corticosteroids administration before anticipated preterm births is one of the most important antenatal therapies available to improve neonatal outcomes. Corticosteroids alter the structural and biochemical physiology of neonates, like surfactant production and lung maturation and thus reduces the requirement and duration of mechanical ventilation. Aims And Objectives: 1.To know the effect of antenatal steroids in minimizing the duration of ventilation in LBW neonates 2.To know the effect of antenatal steroids on assisting in early extubation of LBW neonates. All Low birth weight neonates <2.5 kg who were intubated and on vent Inclusion Criteria: Exclusion Criteria: ilator support. 1.Major congenital anomalies 2.Extubated as a part of withdrawal of care. This Materials And Methods: study was a Prospective Observational Study and was conducted in Rajarajeswari Medical College and Hospital, Bangalore for a duration of 18 months between January 2021 and June 2022.SAMPLE SIZE: n=54, Sample size calculated using considering 95% condence interval and 10% precision. All the parameters Results: i.e., birth weight, gestational age, gender, presence of maternal comorbidities, surfactant and antenatal steroids showed signicant association with number of days of mechanical ventilation in the study. This study was conducted Conclusion: to study the effect of antenatal steroids on mechanical ventilation in low-birth-weight neonates admitted to neonatal intensive care unit and it was found that antenatal steroids had signicant effect on duration of mechanical ventilation; this study has also recognized the factors involved in prolonging the days of mechanical ventilation such as prematurity, doses of antenatal steroids received, low birth weight, lower gestational ag . Recognising such factors can help in preventing complications among the newborns thereby reducing the number of days of mechanical ventilation

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Antenatal Steroid in Preterm Infants with Respiratory Distress Syndrome

Cited by 2 publications

References 19 publications

Risk Factors Affecting Length of Stay in Preterm Infants at Wangaya Regional General Hospital, Indonesia

Risk Factors Affecting Length of Stay in Preterm Infants at Wangaya Regional General Hospital, Indonesia

Study of Effect of Antenatal Steroids on Mechanically Ventilated Low Birth Weight Neonates With Respiratory Distress Admitted to Neonatal Intensive Care Unit(nicu)

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