Antenatal Sonographic Features of Megacystis‐Microcolon‐Intestinal Hypoperistalsis Syndrome

Manco, Lawrence G.; D.O., Paul Osterdahl

doi:10.1002/jcu.1870120915

Cited by 29 publications

(17 citation statements)

References 10 publications

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“…MMIHS was associated with a normal pregnancy course in 45% of continuing pregnancy cases [32,33,34,35]. There was a substantial preterm delivery rate of 55% of continuing pregnancies; however, most of these were late preterm deliveries (35-37 weeks) and scheduled preterm deliveries due to a fetal concern.…”

Section: Discussionmentioning

confidence: 99%

Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome: Case Report and Review of Prenatal Ultrasonographic Findings

Tuzović¹,

Anyane‐Yeboa²,

Mills³

et al. 2014

Fetal Diagn Ther

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Objective: To investigate prenatal ultrasonographic findings associated with megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS). Methods: A PubMed search was performed using the terms ‘MMIHS', ‘MMIH' and ‘prenatal diagnosis'. Results: A total of 50 cases were analyzed. Prenatal diagnosis was achieved in 26% of cases. In 54% of patients with a correct antenatal diagnosis there was a previously affected sibling. Fetal megacystis with or without hydroureteronephrosis was the most common initial ultrasonographic finding (88%). While megacystis eventually complicated all fetal presentations, isolated bilateral hydronephrosis and isolated dilated stomach were noted (in 10 and 2% of cases, respectively) prior to megacystis. The initial sonographic abnormality was most commonly detected (in 70% of patients) in the second trimester. Amniotic fluid was normal in 69% and increased in 27% of cases. Gastrointestinal abnormalities were noted in 24% of pregnancies. Conclusion: MMIHS should be prenatally suspected when fetal megacystis is associated with a normal or increased amount of amniotic fluid and normal external genitalia, especially in the setting of a suggestive family history. Associated gastrointestinal findings support this diagnosis. Isolated bilateral hydronephrosis may precede the development of megacystis. Due to preserved renal function and a general absence of oligohydramnios, no rationale exists for vesicoamniotic shunt placement.

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Section: Discussionmentioning

confidence: 99%

Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome: Case Report and Review of Prenatal Ultrasonographic Findings

Tuzović¹,

Anyane‐Yeboa²,

Mills³

et al. 2014

Fetal Diagn Ther

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“…[6][7][8][9][10] However, such as association has not been noted in most prenatal sonographic reports. 2,8,11,12 Penman and Lilford 13 in 1980 first identified gastric dilatation by sonography in a 16-week fetus affected with MMIHS. It is possible to image the fetal stomach sonographically after the beginning of the second trimester.…”

Section: Discussionmentioning

confidence: 99%

Sonographic findings in a fetus with megacystis-microcolon–intestinal hypoperistalsis syndrome

Chen

Wang

Chuang

1998

J. Clin. Ultrasound

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“…Very large cysts in the fetal abdomen can com press the surrounding organs and interfere with develop ment [1], The prune belly syndrome or megacystis-microcolon-intestinal hypoperistalsis syndrome presenting a large cystic mass has a poor prognosis for long-term sur vival [2,3]. Fetal therapy has been performed to treat large hydrothorax and obstructive uropathy [4][5][6], The hepatic cyst we experienced was solitary according to the classification by Beker [7], A few cases of fetal hepatic cysts occupying most of the abdominal cavity have been reported [8,9].…”

Section: Introductionmentioning

confidence: 99%

Aspiration of Giant Hepatic Cyst in the Fetus in utero

et al. 1997

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A large hepatic cyst was diagnosed in a fetus at 29 weeks of gestation by puncture and aspiration performed under ultrasonographic guidance. This procedure was repeated five times at about 2-week intervals, with a total of 1,446 ml of cystic fluid aspirated. A healthy female infant was delivered vaginally at 40 weeks of gestation. Her Apgar score was 9 at 1 min, and she weighed 2,790 g. On the 14th postnatal day, the hepatic cyst was punctured percutaneously under ultrasonographic guidance, and 119 ml of yellow fluid was aspirated. The cyst was subsequently not visible on computed tomography at 9 months. Surgery was not indicated in this infant, and the cyst was also not detected at the age of 21 month. Thus, treatment in utero appeared to have obviated the need for surgery.

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Antenatal Sonographic Features of Megacystis‐Microcolon‐Intestinal Hypoperistalsis Syndrome

Cited by 29 publications

References 10 publications

Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome: Case Report and Review of Prenatal Ultrasonographic Findings

Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome: Case Report and Review of Prenatal Ultrasonographic Findings

Sonographic findings in a fetus with megacystis-microcolon–intestinal hypoperistalsis syndrome

Aspiration of Giant Hepatic Cyst in the Fetus in utero

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