Antenatal screening for hepatitis B virus infection.

Gad, Magdy A.; Metwally, Mohamed A.; Eissa, Hesham A.; Gehad, Mahmoud A.; Rayan, Moataz M.

doi:10.21608/bmfj.2017.69211

Cited by 7 publications

(13 citation statements)

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“…In our study, multigravidae and primigravidae did not differ signi cantly. This was in agreement with previous study made in Benha [21], and in Nigeria [32]. However, Azhar et al; stated that multigravidae had higher percentage of infection because of multigravidae exposure to many risk factors as multiple pregnancies, blood transfusion, and hospital admission [33].Occupation is a risk factor for HBV infection.…”

Section: Discussionsupporting

confidence: 91%

“…In Ismailia, 18.3% of women were HBcAb positive, and 5% were HBsAg positive [20]. HBsAg seropositivity was found to be 1.56% in Benha in agreement with our study [21]. In Upper Egypt, sero-prevalence of HBsAg was 4.8% in Assiut [22].Findings of the present study were similar to ndings in Libya and Algeria.…”

Section: Discussionsupporting

confidence: 90%

“…Another study was similar to our study in which 80% of HBsAg positive cases were set for surgeries [11]. However, previous surgery was not signi cant risk factor in some other studies [19,21]. Also, other studies detected that dental procedures were no longer signi cant risk factor for HBV.…”

Section: Discussionsupporting

confidence: 85%

“…Taseer et al; reported the association between hepatitis B infection and multiple injection therapy [25]; also, addiction of patient's husband was found to be a signi cant risk factor in another study [21]. Previous studies reported non signi cant difference between HBsAg positive and negative ones as regards history of hospital admission [11,39].…”

Section: Discussionmentioning

confidence: 94%

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Hepatitis B in Pregnant Females. A Cross Sectional Study in Nile Delta, Egypt

Elkadeem

Elnaggar

2021

Preprint

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Background &Aim:Hepatitis B infection is a worldwide health problem. Egypt classified as an area of intermediate endemicity. Hepatitis B has high materno-fetal transmission. The aim of this study was to assess hepatitis B virus infection in Egyptian pregnant females in Nile Delta as regards risk factors and magnitude of the problem.Methods:This cross sectional study was performed on 1948 pregnant females. Historical and sociodemographic data were collected through short simple questionnaire. They were screened for hepatitis B surface antigens. Positive ones were subjected to test hepatitis B e antigen and viral load by real time polymerase chain reaction.Results: Thirty patients (1.54%) were hepatitis B surface antigen positive. Only two of them (6.67%) were hepatitis B e antigen positive with high viral load. Others were hepatitis B e antigen negative and low viral load. Family history of hepatitis B, occupation, age more than 27 years, and history of surgical or dental procedures were significant risk factors associated with hepatitis B acquisition.Conclusion: Screening for hepatitis B is important as a part of antenatal care mainly in the presence of risk factors to follow up mother, and protect fetus so as to prevent wide spread of hepatitis B in Egypt.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 85%

Section: Discussionmentioning

confidence: 94%

See 2 more Smart Citations

Hepatitis B in Pregnant Females. A Cross Sectional Study in Nile Delta, Egypt

Elkadeem

Elnaggar

2021

Preprint

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“…(18) In 2017, a study carried out in Benha University Hospital reported 1.56% HBsAg seropositivity. (19) However, more recently Elkhateeb and Hassan (2018) found a much lower HBsAg seroprevalence of 0.364% in their study done in Minia Governorate. (20) This difference may be explained by different sample sizes and sociodemographic characteristics of the studied females.…”

Section: Discussionmentioning

confidence: 90%

Prevalence of Hepatitis B Virus Among Pregnant Women Attending Antenatal Care in Alexandria

Fekry¹,

Hashish²,

Selim³

et al. 2019

Journal of High Institute of Public Health

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Background & Hepatitis B infection is a very serious public health problem. Perinatal vertical transmission is a common mode of transmission. Infants infected from their mothers will have a very high risk of developing chronic liver disease. Objective(s): To determine the prevalence of hepatitis B virus (HBV) infection and associated risk factors among pregnant females in Alexandria. Methods: A cross sectional study was conducted on 354 pregnant females attending the antenatal care clinics of two gynecology and obstetrics governmental hospitals (with high attendees) in Alexandria. This study was carried out from May 2016 through February 2017. A predesigned questionnaire was used to collect sociodemographic characteristics and possible risk factors. All pregnant women were screened for hepatitis B surface antigen (HBsAg). Samples positive for HBsAg were subjected to hepatitis B e antigen (HBeAg); both were carried out via enzyme linked immunosorbent assay (ELISA). Results: The prevalence of HBsAg was 3.39% (12/354) among studied pregnant females. All HBsAg positive subjects were HBeAg negative. There was no significant statistical association between HBsAg positivity and age, gestational age, history of blood transfusion, previous operation or contact with viral hepatitis infected patients. Conclusion: The prevalence of HBV infection among pregnant women in this study setting is intermediate (3.39%) according to the WHO criteria. HBsAg positivity was not significantly associated with the sociodemographic variables or the studied risk factors. Increasing awareness of HBV transmission and regular screening of pregnant women for HBsAg are recommended.

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