Antenatal fetal death in twin pregnancies: a dangerous condition mainly for the surviving co-twin; a report of four cases

Veyver, I.B.M. Van den; Schatteman, Etienne; Vanderheyden, J.S.; Wiemeersch, J. Van; Meulyzer, P

doi:10.1016/0028-2243(91)90210-c

Cited by 7 publications

(3 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Fetal death is defined as death prior to the complete expulsion or extraction from its mother of a product of conception, irrespective of the duration of pregnancy ( World Health Organisation, 1993 ). Late fetal deaths, after 24 weeks gestation in twin gestations, are associated with major morbidity such as cerebral palsy and various congenital anomalies in the surviving co-conceptus ( Melnick, 1977 ; Hagay et al ., 1986 ; Carlson and Towers, 1989 ; Cherouny et al ., 1989 ; Fusi and Gordon, 1990 ; Van den Veyver et al ., 1990 ; Ishimatsu et al ., 1994 ; Kilby et al ., 1994 ; Lin et al ., 1999 ; Pharoah and Adi, 2000 ; Weiss et al ., 2004 ). Whether or not early fetal death, before 24 weeks gestation, may be associated with similar risks of death or morbidity in the co-twin is less certain.…”

Section: Introductionmentioning

confidence: 99%

Congenital anomalies in multiple births after early loss of a conceptus

2008

View full text Add to dashboard Cite

BackgroundCongenital anomalies are more common in twins than singletons but in the majority, aetiology is not known. Our aim was to test the hypothesis that survivors of an early loss in a multiple conception, compared with all singletons, are at increased risk of congenital anomaly.MethodsData were abstracted from the UK population-based Northern Multiple Pregnancy Register and Northern Congenital Abnormality Survey, 1998–2004.ResultsAmong 3311 twin conceptions, both conceptuses were lost at <16 weeks gestation in 67, and one conceptus in 142 conceptions. Of the 142 singleton survivors, two died in infancy, two were terminated for a congenital anomaly and 11 of 138 had a congenital anomaly (prevalence 915.5 per 10 000 births). There were 197 congenital anomalies among 5948 registered twin births (331.2 per 10 000). The relative risk (RR) of congenital anomalies in a singleton with early loss of a conceptus and twins was 2.40 [95% confidence interval (CI): 1.34–4.29]. There were 4265 infants with a congenital anomaly among the 206 914 singletons [206.1 per 10 000 births: RR twin:singleton 1.61 (95% CI 1.40–1.89)].ConclusionsA highly significant increase in the risk of congenital anomaly in survivors from a multiple conception following early loss of a conceptus supports the hypothesis that many congenital anomalies are associated with monozygotic multiple conceptions.

show abstract

Section: Introductionmentioning

confidence: 99%

Congenital anomalies in multiple births after early loss of a conceptus

2008

View full text Add to dashboard Cite

show abstract

“…While early fetal death of one twin before 10 to 16 weeks of gestation is seen in 10 to 70% of all twin pregnancies ( 1 -3), in later pregnancy intrauterine fetal death is less common, occurring in only 0.5 to 7% (4)(5)(6)(7)(8)(9)(10)(11)(12). In addition to case reports, case series (8, 10, 11, [13][14][15][16][17][18] and compiled statistics (6,19) have been published in recent years, reporting a total of 300 cases of multiple pregnancies with an antepartum death of one fetus.…”

mentioning

confidence: 99%

Twin pregnancies with single fetal death

Prömpeler

Madjar

Klosa

et al. 1994

Acta Obstet Gynecol Scand

View full text Add to dashboard Cite

show abstract

“…Reported cases of cerebral impairment in survivors of twin gestations complicated by fetal death have, almost exclusively, been described in monochorionic twin gestations (2,(7)(8)(9)(12)(13)(14)(15). In the study reported here, the cerebral palsy prevalence in survivors of a twin pregnancy with a fetal death was 80 per 1000, which is greatly in excess of the cerebral palsy prevalence rates of 2 to 2.5 per 1000 in the general population (16), or the rate speci cally in twins of 7-12 per 1000 (3,5).…”

Section: Discussionmentioning

confidence: 99%

Twins and cerebral palsy

Pharoah

2001

Acta Paediatrica

View full text Add to dashboard Cite

In a national follow-up study of twin births, monozygous compared with dizygous twins were at signi cantly increased for both to die in utero, one to die in utero and the co-twin to die in infancy, or both to be livebirths but both die in infancy. The prevalence of cerebral palsy among survivors of a co-twin fetal death was 80.2 and other cerebral impairment was 107.0 per 1000. Many apparently singleton cases of cerebral palsy and impairment may be due to fetal death of a twin that has not been recognized or has been recognized but not registered.

show abstract

Antenatal fetal death in twin pregnancies: a dangerous condition mainly for the surviving co-twin; a report of four cases

Cited by 7 publications

References 17 publications

Congenital anomalies in multiple births after early loss of a conceptus

Congenital anomalies in multiple births after early loss of a conceptus

Twin pregnancies with single fetal death

Twins and cerebral palsy

Contact Info

Product

Resources

About