Antenatal diagnosis, prevalence, and outcome of congenital anomalies of the kidney and urinary tract in Saudi Arabia

Al-Mendalawi,

doi:10.4103/0974-7796.148671

Cited by 1 publication

(1 citation statement)

References 4 publications

(6 reference statements)

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“…Furthermore, this sex differences in the burden of UCA showed a slight enlarging trend because the decrease in ASIRs and ASDRs was more pronounced in females. A distinct male predominance in cases of CAKUTs has been documented in multiple studies 30 , 31 . Studies conducted in China found a high proportion of CAKUTs in male newborns 32 , 33 , and reports from Saudi Arabia also indicated that approximately 66% of CAKUT cases were male 34 .…”

Section: Discussionmentioning

confidence: 87%

Sex difference and risk factors in burden of urogenital congenital anomalies from 1990 to 2019

Huang,

Tang,

Chen

et al. 2023

Sci Rep

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Urogenital congenital anomalies (UCAs) is defined as “any live-birth with a urinary or genital condition” and affects millions of men and women worldwide. However, sex differences and related environmental risk factors in UCAs burden on a global scale have not been assessed. Using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, we estimated prevalence, incidence, mortality and disability-adjusted life years (DALYs) of UCAs from 1990 to 2019 by sex, region, and socio-demographic Index (SDI) in 204 countries and territories. The disease burden of UCAs was also estimated attributable to each risk factor were estimated according to risk exposure. In 2019, UCAs caused 10,200 all-ages deaths (95% UI 7550–13,400). The combined global incidence rate was 8.38 per 1000 (95% UI 5.88–12.0) live births. The ASIR increased slightly, while the ASDR decreased from 1990 to 2019.The UCAs burden varies greatly depending on the development level and geographical location. The UCAs burden was significantly higher in men than in women, and the sex differences showed an enlarging trend. Health risks and issues, including pollution, child and maternal malnutrition, diet habits, unsafe sanitation and water source, were detected to be positively related to UCAs burden. Albeit the age-standardised prevalence, mortality, incidence, and DALYs of UCAs have decreased, they still cause a public health challenge worldwide. The high deaths and DALYs rates in low and low-middle SDI countries highlight the urgent need for improved preventive, diagnostic, and therapeutic measures. Global strategies for enhancing water safety, reducing pollution, and healthy diets are crucial steps in reducing the burden of UCAs.

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