Antenatal Diagnosis of Choroid Plexus Cyst: Suggested Management

Oettinger, Moshe; Odeh, Marwan; Korenblum, Raphael; Markovits, J

doi:10.1097/00006254-199309000-00026

Cited by 13 publications

(7 citation statements)

References 0 publications

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“…an enlarged abnormal bladder in 1 case and a mild pericardial effusion in the other. These findings are in agreement with the suggested management of pregnancies with choroid plexus cysts that was recently proposed in a review of the literature [28], In 2 other cases of trisomy 18, umbilical cord pseudocysts were demonstrated, and both fe tuses had other structural anomalies. This sonographic sign associated with trisomy 18 has already been reported [29].…”

Section: Discussionsupporting

confidence: 90%

Cordocentesis for Rapid Karyotype: 421 Consecutive Cases

Donner

Rypens²,

Paquet³

et al. 1995

Fetal Diagn Ther

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Between October 1985 and December 1993, 421 patients underwent fetal blood sampling for rapid karyotyping (426 samplings, 5 twin pregnancies). The aim of the study was to evaluate cordocentesis in terms of results, complications and additional information in this specific indication especially in case of abnormal pregnancy sonogram. The fetal loss rate possibly related to fetal blood sampling was 1.9%. Abnormal sonograms represented 91% of rapid karyotype indications. Chromosomal abnormalities were found in 9.5% of abnormal sonograms and in 16.9% of fetal structural anomalies (37 cases). The commonest chromosomal abnormality was trisomy 21 (11 cases). In conclusion, cordocentesis is a safe and reliable method for rapid karyotyping although it is associated with more risks than in other indications (congenital infections). The high rate of chromosomal abnormalities pleaded for ultrasonographic screening in a population usually not investigated by cytogenetic studies.

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Section: Discussionsupporting

confidence: 90%

Cordocentesis for Rapid Karyotype: 421 Consecutive Cases

Donner

Rypens²,

Paquet³

et al. 1995

Fetal Diagn Ther

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“…2. Similar algorithms have been reported (Oettinger et al, 1993;Gupta et al, 1995;Shields et al, 1996) using maternal serum screening and ultrasound, although no actual experience with maternal serum screening was reported.…”

Section: Discussionmentioning

confidence: 66%

A role for maternal serum screening in detecting chromosomal abnormalities in fetuses with isolated choroid plexus cysts: a prospective multicentre study

et al. 1999

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“…20,21 Despite the low incidence, CPC has clinical implications for aneuploidy because of an association of choroid plexus with trisomy 18 2,[5][6][7][8][9][10][11][12]22 and trisomy 21. 4,10,13,19,[22][23][24] Researchers have been more concerned with trisomy 18 because the prevalence of CPC for fetuses with trisomy 21 and for the general population are the same.…”

Section: Epidemiologymentioning

confidence: 99%

“…Prenatal karyotyping is recommended when maternal serum screening markers are abnormal and abnormalities are found on sonogram. [3][4][5][6][7][8][9][10][11][12] However, the presence of CPC on sonogram without other abnormalities is a cause of controversy and should be recognized in early pregnancy as an important issue which must be addressed with proper management and care.…”

mentioning

confidence: 99%