Antenatal and postnatal risk factors for neonatal hypertension and infant follow-up

Seliem, Wael; Falk, Michael C.; Shadbolt, Bruce; Kent, Alison

doi:10.1007/s00467-007-0603-2

Cited by 88 publications

(80 citation statements)

References 48 publications

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“…A 2.8% prevalence of hypertension in our subjects in three consecutive visits is similar to a study done by Friedman and Hustead which is 2.6% but twice as high as the Australian study which is 1.3% (11,12). In most reports the prevalence of hypertension in survivors of the neonatal intensive care units ranges from 0.2-3% (13)(14)(15)(16)(17)(18). This is in agreement with our finding.…”

Section: Discussionsupporting

confidence: 93%

Patterns of Blood Pressure in Infants who Survived from a Neonatal Intensive Care Unit

Shimelis¹

2017

ijSciences

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Section: Discussionsupporting

confidence: 93%

Patterns of Blood Pressure in Infants who Survived from a Neonatal Intensive Care Unit

Shimelis¹

2017

ijSciences

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“…Indeed, AS have been associated with increased postnatal BP in preterm infants (6,10,18,19). Correspondingly, the incidence of hypertension has been reported to increase (20), whereas both hypotension and the need for treatment of hypotension decrease (6,7,18,(21)(22)(23) with AS. Conversely, not all studies confirm the positive effect of AS on postnatal BP (8,24) and the need for treatment of hypotension (17).…”

mentioning

confidence: 99%

Early Postnatal Blood Pressure in Preterm Infants: Effects of Chorioamnionitis and Timing of Antenatal Steroids

et al. 2009

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Previous studies suggest postnatal blood pressure in preterm infants to be decreased by chorioamnionitis and increased by antenatal steroids (AS). We examined the adjusted effects of both antenatal modulators on postnatal blood pressure (BP), with separate effects reported for histologic chorioamnionitis with or without fetal involvement and timing of AS. General characteristics, BP, and heart rate values during the first 72 h after birth were obtained from 271 infants with gestational age Յ32.0 wk. In unadjusted analyses, chorioamnionitis was associated with lower BP, most prominently so in infants with fetal involvement, without an effect on hypotension incidence. AS increased BP and decreased the incidence of hypotension when administered within 7 d before birth. In a multivariable mixed model analysis, the AS effect remained significant, whereas chorioamnionitis was not independently predictive of postnatal BP. Other variables associated with increased postnatal BP were gestational age and umbilical artery pH, whereas hemolysis, elevated liver enzymes, low platelets syndrome was associated with decreased BP.

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“…The other factors which have been implicated for effecting neonatal BP are maternal drug intake, Apgar scores, hypertension in mother during pregnancy, delivery method, type of anaesthesia given to mother during new-born birth [12,13], neonatal drugs and neonatal morbidities. When neonatal BP is high and before stating it as NHT, all the BP effecting factors should be taken care of right interpretation of neonatal BP [14].…”

Section: What Is the Normal Bp In Neonatal Population?mentioning

confidence: 99%

Hypertension in Neonates: Need for Future Research

Sharma¹

2017

J Neonatal Biol

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Drug ClassName of drug and Recommended dose Fast onset of action Calcium-channel blockersNicardipine ( 95th and 99 th percentile) and mild depending upon the value of BP and end-organ dysfunction and treatment will depend upon the severity of presentation ( Figure 6) [3,5,17,22,23]. When is the surgical Intervention needed for neonatal HT?The indications for surgical treatment of NHT are few and includes renal malformations (renal vessels thrombosis/stenosis, polycystic kidney and renal tumors) and cardiovascular malformations like coarctation of aorta [26][27][28][29][30][31]. How is the prognosis of neonate with HT?The prognosis of NHT depends upon the cause of HT i.e. if cause of iatrogenic than the NHT get resolved once the precipitating factor is removed. If the neonate have features of end organ dysfunction than outcome is not favourable [28]. If the cause of NHT is renal, then HT persists in childhood. Blood pressure usually gets normalized in follow up of neonate who had NHT secondary to bronchopulmonary dysplasia [32]. ConclusionNeonatal HT has no clear definition with no proper treatment guidelines. Blood pressure should be measured in described standard manner, with the health care personal taking BP measurement should have sound knowledge of the method. The etiology of neonatal HT should be sought and before starting anti-hypertensive medication, treatable causes of neonatal HT should be sought. The commonest etiology for neonatal hypertension is reno vascular disease. The diagnostic approach includes detailed history taking (prenatal, perinatal and postnatal), clinical examination and laboratory investigations. ACE inhibitors are first line of drugs and should be used after ruling out renal artery stenosis.

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Antenatal and postnatal risk factors for neonatal hypertension and infant follow-up

Cited by 88 publications

References 48 publications

Patterns of Blood Pressure in Infants who Survived from a Neonatal Intensive Care Unit

Patterns of Blood Pressure in Infants who Survived from a Neonatal Intensive Care Unit

Early Postnatal Blood Pressure in Preterm Infants: Effects of Chorioamnionitis and Timing of Antenatal Steroids

Hypertension in Neonates: Need for Future Research

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