2002
DOI: 10.1067/mtc.2002.124994
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Antegrade selective cerebral perfusion during operations on the thoracic aorta: Factors influencing survival and neurologic outcome in 413 patients

Abstract: Antegrade selective cerebral perfusion is an effective method of brain protection. Cerebral perfusion times of longer than 90 minutes were not associated with an increased risk of hospital mortality or poorer neurologic outcome. Urgency status and recent history of central neurologic events were retained as important risk factors for hospital mortality and neurologic outcome.

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Cited by 125 publications
(85 citation statements)
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“…There were some major, independent risk factors reported for PND after the aortic arch operation per- 12,17) history of cerebrovascular accident, 8,9,12,17) male, 8) and older age (>60 years).…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…There were some major, independent risk factors reported for PND after the aortic arch operation per- 12,17) history of cerebrovascular accident, 8,9,12,17) male, 8) and older age (>60 years).…”
Section: Discussionmentioning
confidence: 99%
“…SCP prevents ischemic damage to the brain during circulatory arrest, so it facilitates complicated aortic arch replacement, resulting in a significant reduction of mortality and morbidity for aortic arch repair. [7][8][9][10][11][12] However, it has some disadvantages including greater complexity, a cumbersome operative field, and an inherent risk for cerebral embolism an inherent risk for cerebral embolism caused by insertion of perfusion cannula for SCP. In this study, we retrospectively examined factors that influence postoperative PND and in-hospital mortality after TAR surgery preformed with separate arch vessel grafting during SCP.…”
Section: Discussionmentioning
confidence: 99%
“…At risk, however, is a possible increase in the embolic load to the brain. Recently, excellent clinical results in terms of mortality and neurological deficit have been reported by several groups using SACP [7][8][9][10][11] that suggest superiority over either HCA alone or HCA supplemented by retrograde cerebral perfusion.…”
mentioning
confidence: 99%
“…Previous studies have identified risk factors for TND as being preoperative cerebrovascular disease, patient age, undergoing an emergent operation, and a long duration of CA. 4,[15][16][17][18] The present study showed that limiting the duration of cerebral ischemia could reduce the incidence of neurologic complications. The use of SCP for DTA or TAA surgery, resulting in a shorter period of cerebral ischemia, may reduce the risk of TND.…”
Section: Resultsmentioning
confidence: 88%