Answer to the Letter to the Editor of Manu N. Capoor et al. concerning “Low virulence bacterial infections in cervical intervertebral discs: a prospective case series” by Chen Y, Wang X, Zhang X, et al. (Eur Spine J; 2018: doi: 10.1007/s00586-018-5582-4)
“…Moreover, 6-15% of RA patients have a risk of developing ILD, and the risk increases with prolonged RA duration. 12 Death risk was found to be 3 times higher in RA patients with ILD compared to RA patients who do not have ILD. Given the high mortality associated with ILD, early diagnosis and appropriate intervention is critical.…”
Krebs von den Lungen-6 (KL-6) is one of the mucins associated with interstitial lung disease. We aimed to assess the value of KL-6 as a marker for detecting the presence of interstitial lung disease in Egyptian rheumatoid arthritis patients and to evaluate its ability to assess severity in different grades of interstitial lung disease. The study included 89 rheumatoid arthritis patients; 64 patients with interstitial lung disease and 25 patients without interstitial lung disease. Serum levels of KL-6 were assessed using enzyme linked immunosorbent assay. Levels of KL-6 were higher in patients with interstitial lung disease compared to patients without interstitial lung disease (P< 0.001). KL-6 levels were significantly higher in grade 4 patients than those in grades 1 and 2. Also, KL-6 levels were significantly higher in grade 3 patients than those in grades 1 and 2. Kl-6 levels were also higher in grade 2 patients compared to grade 1 patients. Finally, no difference was observed between grade 4 patients and grade 3 patients. KL-6 levels were significantly higher in usual interstitial pneumonia pattern compared other patterns (P=0.015). In conclusion, KL-6 is a potential circulating biomarker that may have a substantial role in detecting the presence and evaluating the severity of interstitial lung disease among rheumatoid arthritis patients.
“…Moreover, 6-15% of RA patients have a risk of developing ILD, and the risk increases with prolonged RA duration. 12 Death risk was found to be 3 times higher in RA patients with ILD compared to RA patients who do not have ILD. Given the high mortality associated with ILD, early diagnosis and appropriate intervention is critical.…”
Krebs von den Lungen-6 (KL-6) is one of the mucins associated with interstitial lung disease. We aimed to assess the value of KL-6 as a marker for detecting the presence of interstitial lung disease in Egyptian rheumatoid arthritis patients and to evaluate its ability to assess severity in different grades of interstitial lung disease. The study included 89 rheumatoid arthritis patients; 64 patients with interstitial lung disease and 25 patients without interstitial lung disease. Serum levels of KL-6 were assessed using enzyme linked immunosorbent assay. Levels of KL-6 were higher in patients with interstitial lung disease compared to patients without interstitial lung disease (P< 0.001). KL-6 levels were significantly higher in grade 4 patients than those in grades 1 and 2. Also, KL-6 levels were significantly higher in grade 3 patients than those in grades 1 and 2. Kl-6 levels were also higher in grade 2 patients compared to grade 1 patients. Finally, no difference was observed between grade 4 patients and grade 3 patients. KL-6 levels were significantly higher in usual interstitial pneumonia pattern compared other patterns (P=0.015). In conclusion, KL-6 is a potential circulating biomarker that may have a substantial role in detecting the presence and evaluating the severity of interstitial lung disease among rheumatoid arthritis patients.
“…Interestingly, the plasmonic substrate was protected with polymer films as a proof-of-concept for developing more stable and wearable sensors for on-site monitoring. Detection of the pesticide thiram was achieved employing polydopamine spheres coated with a gold shell bearing gaps and voids (hotspots) (Chen et al, 2018). The nanowaxberry substrate (see Figure 1B) achieved a LOD of 2.4 µg/L in spiked environmental water (river water).…”
Section: Sers Detection Of Organic Pollutantsmentioning
Water is a matter of vital importance for all developed countries due to the strong impact on human health and aquatic, wetlands and terrestrial environments. Therefore, the monitoring of water quality is of tremendous importance. The enormous advantages that Surface-enhanced Raman scattering (SERS) spectroscopy offers, such as fingerprint recognition, multiplex capabilities, high sensitivity, and selectivity or non-destructive testing, make this analytical tool very attractive for this purpose. This minireview aims to provide a summary of current approaches for the implementation of SERS sensors in monitoring organic and inorganic pollutants in water. In addition, we briefly highlight current challenges and provide an outlook for the application of SERS in environmental monitoring.
“…According to the spot on CCD, the sensor using its own algorithm to measure the displacement value of the object. In the Fig.1, L is the distance from the intersection of the optical axis of the laser beam and the receiving optical axis to the front surface of the receiving lens [7].…”
Section: The Measurement Principle Of Laser Displacement Sensormentioning
confidence: 99%
“…Laser displacement measurement system is composed of laser diode, optical system, linear CCD sensor, digital signal processor and external interface, etc. [7]. The sensor uses analog triangulation technology to detect the displacement and thickness.…”
Abstract. For large heavy-duty rotary table, in order to improve the machining precision of the workbench in practical work, the workbench is usually set above the oil film with stable thickness.
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