Answer to the comments by Eric J. Grant et al. in “Radiation unlikely to be responsible for high cancer rates among distal Hiroshima A-bomb survivors”

Miyao, Masaru; Watanabe, Tetsu; Honda, Ryumon; Yamada, Yuichi

doi:10.1007/s12199-009-0088-7

Cited by 1 publication

(1 citation statement)

References 5 publications

(11 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These analyses reported by RERF had some problems: (1) LSS did not investigate the residual radiation value in each subject who had been exposed to the A-bomb, and (2) showed the results for A-bomb survivors in comparison with a non-zero exposed group as an unexposed group [20]. The LSS report, therefore, may have calculated the background risk as higher than it actually was [5,22]. We estimated SMRs compared with a genuine non-exposed control group by using the Japanese population.…”

Section: Discussionmentioning

confidence: 99%

Cancer mortality among atomic bomb survivors exposed as children

Goto

Watanabe

Miyao

et al. 2011

Environ Health Prev Med

Self Cite

View full text Add to dashboard Cite

Objectives To compare cancer mortality among A-bomb survivors exposed as children with cancer mortality among an unexposed control group (the entire population of Japan, JPCG). Methods The subjects were the Hiroshima and Nagasaki A-bomb survivor groups (0-14 years of age in 1945) reported in life span study report 12 (follow-up years were from 1950 to 1990), and a control group consisting of the JPCG. We estimated the expected number of deaths due to all causes and cancers of various causes among the exposed survivors who died in the follow-up interval, if they had died with the same mortality as the JPCG (0-14 years of age in 1945). We calculated the standardized mortality ratio (SMR) of A-bomb survivors in comparison with the JPCG.Results SMRs were significantly higher in exposed boys overall for all deaths, all cancers, leukemia, and liver cancer, and for exposed girls overall for all cancers, solid cancers, liver cancer, and breast cancer. In boys, SMRs were significantly higher for all deaths and liver cancer even in those exposed to very low doses, and for all cancers, solid cancers, and liver cancer in those exposed to low doses. In girls, SMRs were significantly higher for liver cancer and uterine cancer in those exposed to low doses, and for leukemia, solid cancers, stomach cancer, and breast cancer in those exposed to high doses. Conclusions We calculated the SMRs for the A-bomb survivors versus JPCG in childhood and compared them with a true non-exposed group. A notable result was that SMRs in boys exposed to low doses were significantly higher for solid cancer.

show abstract

Section: Discussionmentioning

confidence: 99%