Another Choice for Aortic Valve Disease in Pediatric Patients

Jia, Bing; Zhang, Huifeng; Huang, Jiaxi

doi:10.1016/j.athoracsur.2021.01.080

Cited by 3 publications

(9 citation statements)

References 2 publications

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“…Although the early and mid-term results are successful, data for long-term morbidity and reoperation rate have not yet been published. 8,9 A wide variety of surgical repair techniques are available for congenital or acquired aortic valve stenosis and insufficiency in children. 2 These techniques have acceptable results in the medium and long term.…”

Section: Discussionmentioning

confidence: 99%

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Urgent aortic valve neocuspidization using the Ozaki procedure in an infant with native aortic valve endocarditis

et al. 2023

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Native valve aortic endocarditis is rarely seen in the paediatric population. Although, the first-line of treatment is medical, surgical intervention may be indicated in patients with unrepairable valvular and subvalvular disease. Recently, the aortic valve neocuspidization (AVNeo) procedure has gained popularity both in adult and children in whom other repair techniques are not feasible. In this case report, we present an urgent aortic valve replacement using the AVNeo technique in a critically ill infant with a small annulus, severe left ventricular outflow tract stenosis, and severe aortic regurgitation.

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Section: Discussionmentioning

confidence: 99%

“…Although the early and mid-term results are successful, data for long-term morbidity and reoperation rate have not yet been published. 8,9…”

Section: Discussionmentioning

confidence: 99%

Urgent aortic valve neocuspidization using the Ozaki procedure in an infant with native aortic valve endocarditis

et al. 2023

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“…Then the thymus was exposed and then excised if necessary. A large piece of pericardium with an adequate area was harvested, and treated with 0.6% glutaraldehyde solution with a buffer for 10 minutes followed by three times of rinsing with normal saline solution as preparation for use ( Figure 2A ) ( 16 ). The pericardium was fixed without tension.…”

Section: Methodsmentioning

confidence: 99%

“… Procedures of our technique. Reprinted/adapted with permission from ref ( 16 ). The Society of Thoracic Surgeons.…”

Section: Methodsmentioning

confidence: 99%

“…After careful exploration, the unrepairable native aortic valve was then excised. The size of the annulus was measured ( Figure 2B ) ( 16 ). Then a self-designed template with a corresponding size to the annulus was selected to draw the shape of new valve cusps on the treated pericardium together with some important marking points, the midpoint of a suturing margin and the free margin ( Figure 2C ) ( 16 ).…”

Section: Methodsmentioning

confidence: 99%

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A midterm follow-up study of the application of a confluent aortic valve neocuspidization technique with pericardium in children

Huang,

Zhang,

Jia

et al. 2023

Transl Pediatr

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Background The treatment of aortic valve diseases in children remains a great challenge. We aim to report outcomes and midterm follow-up data of our confluent neocuspidization technique with pericardium for aortic valve replacement (AVR) in children. Methods A retrospective analysis was performed on all 20 children who underwent the confluent neocuspidization technique with pericardium at Children’s Hospital of Fudan University from March 2017 to May 2022. Outcome measures included echocardiographic measurements, surgical intervention, and mortality. Results A total of 20 patients (17 males vs. 3 females), with a median age of 7.5 years [min–max, 0.3–12 years; interquartile range (IQR), 4.4–9.7 years], a median body weight of 24.0 kg (min–max, 6.0–52.3 kg; IQR, 15.6–31.0 kg), and median aortic valve annulus size before surgery of 19.0 mm (min–max, 11.0–25.0 mm; IQR, 17.1–21.5 mm), underwent the neocuspidization technique with pericardium (17 autologous pericardia and 3 bovine patch). With 50% of bicuspid aortic valve and 50% of tricuspid, they were respectively diagnosed as aortic stenosis (AS) (7/20, 35%), aortic regurgitation (AR) (8/20, 40%) and mixed AS and AR (AS & AR) (5/20, 25%). The median postoperative follow-up time was 19 months (min–max, 5–61 months; IQR, 16.3–35 months). The peak pressure gradient across the aortic valve decreased from 81.0±37.0 mmHg in AS group and AS & AR group before surgery to 25.9±15.8 mmHg within 24 hours after surgery (P<0.001) and was mostly around 25 mmHg during follow-up. All patients presented mild or less than mild regurgitation within 24 hours after surgery. There were no hospital mortalities. Three patients needed reintervention during follow-up. There was one late death related to mitral valve stenosis. Conclusions Though the confluent neocuspidization technique with pericardium provided immediate relief of significant AS or regurgitation, the midterm outcome was suboptimal. More research is needed to find the optimal material for AVR.

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Curb Your Enthusiasm for the Ozaki Procedure in Small Children

Alsoufi

2022

The Annals of Thoracic Surgery

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Another Choice for Aortic Valve Disease in Pediatric Patients

Cited by 3 publications

References 2 publications

Urgent aortic valve neocuspidization using the Ozaki procedure in an infant with native aortic valve endocarditis

Urgent aortic valve neocuspidization using the Ozaki procedure in an infant with native aortic valve endocarditis

A midterm follow-up study of the application of a confluent aortic valve neocuspidization technique with pericardium in children

Curb Your Enthusiasm for the Ozaki Procedure in Small Children

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