Anorexia nervosa in a long-term perspective: results of the Heidelberg-Mannheim Study.

Deter, Hans‐Christian; Herzog, Wolfgang

doi:10.1097/00006842-199401000-00003

Cited by 156 publications

(113 citation statements)

References 21 publications

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“…Twenty-four of the patients were males. The ascertainment, diagnostic assessment according to DSM-III-R, and outcome of these study cohorts have been described in detail elsewhere (4)(5)(6)(7)(8)(9). For the present analysis, all 24 of the males, seven females with additional somatic diseases at referral, and seven pretreated females whose body mass indexes at referral were greater than 17.5 kg/m 2 were excluded; 31 additional females could not be traced at follow-up.…”

Section: Methodsmentioning

confidence: 99%

“…Obviously, focusing on weight outcome alone is unsuitable for assessment of the general outcome of anorexia nervosa, which for the patients in the present study has been described elsewhere (5)(6)(7)(8)(9). Nevertheless, persistence of underweight has far-reaching implications justifying attempts to adequately define a poor weight outcome.…”

Section: Figure 1 Relationship Of Body Mass Indexes (Kg/m 2 ) At Refmentioning

confidence: 99%

See 1 more Smart Citation

Prediction of low body weight at long-term follow-up in acute anorexia nervosa by low body weight at referral

Himmelmann¹,

Herzog²,

Herpertz‐Dahlmann³

et al. 1997

AJP

118

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S ingle follow-up studies have identified a low body weight at referral as a poor prognostic indicator for intermediate or long-term follow-up (1, 2). Morgan and Russell (3) observed an association between low body weight (less than 60% average body weight, roughly equivalent to a body mass index of 12.5 kg/m 2 in females aged 17-19 years) at referral and poor general outcome after 5 years. In a previous study (4), we found that 24 patients with body mass indexes less than 13 kg/m 2 at referral had significantly lower body mass indexes at follow-up than 57 patients who had higher body mass indexes at referral; the mean follow-up period was 11.7 years. Possible explanations for the discrepancies regarding the prognostic implications of a low body weight at referral include small sample sizes and crude categorizations of the weight outcome.The hypothesis of the present study was that a low body mass index at referral predicts a low body mass index at long-term follow-up. To test this hypothesis we assessed body mass indexes at referral and at follow-up in a large study group (N=272) to determine their interrelationship and to assess the influence of age at onset, age at referral, and age at follow-up, respectively. METHODThe study group was a composite of five study cohorts with a total of 341 consecutively ascertained inpatients with anorexia nervosa. Twenty-four of the patients were males. The ascertainment, diagnostic assessment according to DSM-III-R, and outcome of these study cohorts have been described in detail elsewhere (4-9). For the present analysis, all 24 of the males, seven females with additional somatic diseases at referral, and seven pretreated females whose body mass indexes at referral were greater than 17.5 kg/m 2 were excluded; 31 additional females could not be traced at follow-up. The final study group included 272 females whose body mass indexes at referral and body mass indexes at follow-up or time of death were available. Their mean ages at referral and at follow-up were 16.7 years (SD=4.5, range=10-42) and 26.2 years (SD=6.9, range=15-58), respectively. Mean length of follow-up was 9.5 years (SD=5.3, range=0-33.6) and included the survival times of the 12 patients who had died after a mean of 4.2 years (SD=4.0, range=0-13). Deaths were related to the sequelae of emaciation in 10 patients and to suicide in two patients.The patients' body mass indexes at referral were plotted against their body mass indexes at follow-up and Pearson's correlation was calculated. Body mass indexes were plotted in 1-kg/mg 2 intervals from 9 to 27 kg/mg 2 . Patients with low body mass indexes at referral were compared with patients with higher body mass indexes at referral by using repeated U tests. Significance was adjusted for multiple testing (10). We also charted the proportion of patients whose body mass indexes at follow-up were 17.5 kg/m 2 or less, those whose body mass indexes were in the fifth percentile or below, and those whose body mass indexes were in the 10th percentile or below. Body mass index ...

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Section: Methodsmentioning

confidence: 99%

Section: Figure 1 Relationship Of Body Mass Indexes (Kg/m 2 ) At Refmentioning

confidence: 99%

Prediction of low body weight at long-term follow-up in acute anorexia nervosa by low body weight at referral

Himmelmann¹,

Herzog²,

Herpertz‐Dahlmann³

et al. 1997

AJP

118

View full text Add to dashboard Cite

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“…There are reports linking impulsivity [48] as well as purging behaviors in ED to greater overall morbidity and worse outcome [49]. Some suggested that dysfunctional interactions between serotonin and dopamine systems in the prefrontal cortex may be an important mechanism underlying the link between impulsivity and ED symptoms [3,7].…”

Section: Discussionmentioning

confidence: 99%

Differences in Impulsivity between Females Diagnosed with Eating Disorders and Healthy Subjects

Golan¹

2015

JPCPY

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Objectives: This cross-sectional study investigates the tendencies toward impulsivity and self-control over the entire spectrum of the different eating disorders in comparison to healthy and recovered subjects. Methods:The study included 116 women, aged 18-35. Participants filled seven self-report questionnaires to assess eating disorders features and tendencies toward impulsivity and self-control and two computerized tasks (Go/No Go and Cognitive Delay Discounting) to examine motoric impulsivity. Results:There was a hierarchy of occurrence of impulsivity in the different categories of eating disorders. Cognitive impulsivity as well as motor impulsivity and global score of impulsivity were most prominent in the anorexia nervosa binging type. This hierarchy was correlated with the eating disorders symptoms. The lowest score in motor impulsivity was observed among restrictive patients with anorexia and the highest among patients with binging-purging anorexia, while all other groups were in between. Those with binging-purging anorexia demonstrated significantly different behavior in short term delays: they were less willing to delay gratification in comparison to other participants who demonstrated preference for the higher delayed reward. The impulse regulation and the ineffectiveness scores of both anorextic groups were higher in comparison to the other groups. These two variables were highly correlated with attentional impulsiveness. Conclusion:These findings suggest that binging restricting behaviors may be seen as lying on opposite ends of a spectrum of impulsive behaviors. Individuals with AN-BP appear to have more in common with BN individuals as they share the tendency to display greater response Disinhibition and produce more impulsive behaviors. Since at this stage only a small sample size was analyzed these results are considered preliminary.

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“…[24] Benzer şekilde 105 hastanın 13.5 yıl izlendiği çalışmada gerçekleşen 25 ölümün 5'inin (kaba ölüm hızı: %4.8) ; 84 hastanın 12 yıl sonra değerlendirildiği çalışmada gerçekleşen 9 ölümün 2'sinin özkıyıma bağlı olduğu bulunmuştur (kaba ölüm hızı: %2.4). [25,26] Amerika Birleşik Devletlerinde (A.B.D) 1885 yeme bozukluğu olgusu (anoreksiya nervoza: 177, bulimiya nervoza: 906, başka türlü adlandırılama-yan yeme bozukluğu: 802) 8 ila 25 yıllık bir dönemin ardından Ulusal Ölüm İndeksinin bilgisayar kayıtlarıyla bağlantı kurularak araştırılmıştır. [27] Bu çalışmada, kaba ölüm hızları anoreksiya nervoza için %4, bulimiya nervoza için %3.9 ve başka türlü adlandırılamayan yeme bozuklukları için %5.2 olarak saptanmıştır.…”

Section: Sıklığıunclassified

Suicidal Behavior in Eating Disorders

Öncü¹,

Sakarya²

2013

Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychia

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ÖZETYeme bozukluklarında özkıyıma bağlı ölüm oranları oldukça yüksektir. Yeme bozukluklarında özkıyıma bağlı kaba ölüm hızı %0 ile %5.3 arasında değiş-mektedir. Yeme bozukluklarında özkıyım davranışı ile ilişkili etmenler, yeme bozukluğunun alt tipi, ek tanıların varlığı, ilaç metabolizmasının hızlı olması, belli kişilik özellikleri, çocuklukta istismar öyküsü ve belli aile tutumlarıdır. Bu etmenler dışında depresif bozukluklar, alkol-madde kötüye kullanımı ve kişilik bozuklukları gibi diğer ruhsal bozuklukların bulunması da yeme bozukluklarında özkıyım riskini artırmaktadır. Bu yazıda yeme bozukluklarında özkıyım davranışı ve ile ilişkili etmenler kısaca gözden geçirilmiştir. Anahtar Sözcükler: Özkıyım, yeme bozuklukları, anoreksiya nervoza ABSTRACT Suicide associated mortality rates are notable for eating disorders. Crude mortality rate associated with suicide, varies between 0% and 5.3% in patients with eating disorders. Prominent risk factors for suicidal behavior among these patients are subtype of the eating disorders, comorbid psychiatric diagnosis (e.g. depression, alcohol and substance abuse, personality disorders), ultrarapid drug metabolism, history of childhood abuse and particular family dynamics. In this article, suicidal behavior and associated factors in eating disorders are briefly reviewed.

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Anorexia nervosa in a long-term perspective: results of the Heidelberg-Mannheim Study.

Cited by 156 publications

References 21 publications

Prediction of low body weight at long-term follow-up in acute anorexia nervosa by low body weight at referral

Prediction of low body weight at long-term follow-up in acute anorexia nervosa by low body weight at referral

Differences in Impulsivity between Females Diagnosed with Eating Disorders and Healthy Subjects

Suicidal Behavior in Eating Disorders

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