Anorectal motor disorders

Massive lower gastrointestinal bleeding associated with solitary rectal ulcer in a patient with Behçet’s disease

“…Due to its complex clinical and endoscopic findings, a biopsy and an histopathological examination are required to confirm the diagnosis. The main pathological findings are fibromuscular dysplasia, collagenous and muscle cell infiltration in the lamina propria, a thickening of muscularis mucosa and deformations in crypt units (8). Although there are various treatment options that range from conservative therapy to surgery, so far no therapy has proved to be more effective than the others.…”

Effective treatment of solitary rectal ulcer syndrome using argon plasma coagulation

“…This is especially difficult when the ulceration is large [2, 4]. However, there are some reports describing the effectiveness of pharmacotherapy, which suggest that local pharmacotherapy in SRUS does not give good results, but there are no prospective studies evaluating this method.…”

“…The most popular hypothesis claims that this is a secondary disease following rectal prolapse (overt or latent, mucosal or complete prolapse) and it is a result of defecation disorders. Disorders of muscle synergy related to defecation are seen in 25–82% of patients with SRUS [ 2 ]. Sharara et al .…”

“…The diagnosis of SRUS is usually late, mainly because of its common asymptomatic initial course [ 1 , 2 , 5 ]. Later symptoms are the same as in other – more common – disorders of the anorectum and are often ignored.…”

Role of electromyography and functional electrical stimulation in the treatment of anorectal diseases

“…The pathophysiology of functional disorders of the pelvic floor The pathophysiology of functional pelvic floor muscles is complex and in many diseases remains unclear. Increased tension of pelvic floor muscles at rest and reduced number of active units significantly correlate with vascularization disturbances, which underly with the many pathologies of the area, such as rectal ulceration, perianal infections, and chronic anal fissure (1).…”