Anomaly handling and the politics of gene drives

Evans, Sam Weiss; Palmer, Megan J.

doi:10.1080/23299460.2017.1407911

Cited by 21 publications

(22 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In short, decisions about the use of gene drive organisms for any application will require thoughtful and inclusive deliberation [60]. The promise of these technologies is great, yet the uncertainty about success outcomes is clearly considerable.…”

Section: Discussionmentioning

confidence: 99%

“…The development of these technologies is outpacing the local, national and global structures that govern biotechnology in the environment [2], and some scholars describe them as 'anomalies' in the biotechnology regulation ecosystem [60]. Gene drive organisms will not only cross political jurisdictions, but they will also influence shared environments and decisions about them should reflect these complex implications [2,59].…”

Section: Societymentioning

confidence: 99%

See 1 more Smart Citation

Sustainability as a Framework for Considering Gene Drive Mice for Invasive Rodent Eradication

et al. 2019

View full text Add to dashboard Cite

Gene drives represent a dynamic and controversial set of technologies with applications that range from mosquito control to the conservation of biological diversity on islands. Currently, gene drives are being developed in mice that may one day serve as an important tool for reducing invasive rodent pests, a key threat to island biodiversity and economies. Gene drives in mice are still in development in laboratories, and wild release of modified mice is likely a distant reality. However, technological changes outpace the existing capacity of regulatory frameworks, and thus require integrated governance frameworks. We suggest sustainability—which gives equal consideration to the environment, economy, and society—as one framework for addressing complexity and uncertainty in the governance of emerging gene drive technologies for invasive species management. We explore the impacts of rodent gene drives on island environments, including potential conservation and restoration of island biodiversity. We outline considerations for rodent gene drives on island economies, including impacts on agricultural and tourism losses, and reductions in biosecurity costs. Finally, we address the social dimension as an essential space for deliberation that will be integral to evaluating the potential deployment of gene drive rodents on islands.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Societymentioning

confidence: 99%

Sustainability as a Framework for Considering Gene Drive Mice for Invasive Rodent Eradication

et al. 2019

View full text Add to dashboard Cite

show abstract

“…Gene drives were initially proposed for the control of insect vectors for human diseases (Gantz et al, 2015;Neve, 2018), but recent work suggest that they could provide major economic benefits to the agricultural sector (Collins, 2018;Neve, 2018). However, while there is potential for gene drives to eliminate or suppress pest species, their widespread uptake and use could lead to problems in their application and governance (Evans and Palmer, 2018). One concern is that commercial interests will seek to maintain sales of agrochemicals by configuring gene drives to reduce chemical resistance in target pest insects and weeds as opposed to causing sterility in those species.…”

Section: Agricultural Gene Drivesmentioning

confidence: 99%

Bioengineering horizon scan 2020

Kemp

Adam

Boehm

et al. 2020

eLife

Self Cite

View full text Add to dashboard Cite

Horizon scanning is intended to identify the opportunities and threats associated with technological, regulatory and social change. In 2017 some of the present authors conducted a horizon scan for bioengineering (Wintle et al., 2017). Here we report the results of a new horizon scan that is based on inputs from a larger and more international group of 38 participants. The final list of 20 issues includes topics spanning from the political (the regulation of genomic data, increased philanthropic funding and malicious uses of neurochemicals) to the environmental (crops for changing climates and agricultural gene drives). The early identification of such issues is relevant to researchers, policy-makers and the wider public.

show abstract

“…In gene drive research, genetically modified organisms contain a transgene that can be passed on up to 100% of their progeny. The prospect of gene drive research moving from a laboratory-only setting to being used "in the field" is now raising questions about the adequacy of the policy frameworks in place to manage and guide the research and its outcomes responsibly ( Evans & Palmer, 2018 ; James et al ., 2018 ; Kuzma et al ., 2018 ).…”

Section: Introductionmentioning

confidence: 99%

Providing a policy framework for responsible gene drive research: an analysis of the existing governance landscape and priority areas for further research

Thizy¹,

Coche²,

Vries³

2020

Wellcome Open Res

View full text Add to dashboard Cite

The progress in gene drive research has made the possibility of a future release in the environment probable. This prospect is raising new questions related to the adequacy of the policy frameworks in place to manage and regulate the research and its outcomes responsibly. A number of international mechanisms are exploring how to evaluate this technology. Amongst them, the Convention of Biological Diversity and the Cartagena Protocol, the review mechanisms of the World Health Organisation, and the International Union for Conservation of Nature are offering international fora for dialogue, while regional entities, such as the African Union, are developing specific frameworks to build their preparedness for oversight of gene drive organisms. In this manuscript, we review the existing regulatory landscape around gene drive research and map areas of convergence and divergence, as well as gaps in relation to guidelines for community engagement in gene drive research.

show abstract

Anomaly handling and the politics of gene drives

Cited by 21 publications

References 43 publications

Sustainability as a Framework for Considering Gene Drive Mice for Invasive Rodent Eradication

Sustainability as a Framework for Considering Gene Drive Mice for Invasive Rodent Eradication

Bioengineering horizon scan 2020

Providing a policy framework for responsible gene drive research: an analysis of the existing governance landscape and priority areas for further research

Contact Info

Product

Resources

About