Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA): a surgical certainty

Butt, Arthur J.; Amanullah, Muhammad Muneer; Amanullah, Mehnaz Atiq; Hasan, Asif; Ahmad, Waris

doi:10.5455/jpma.34200

Cited by 4 publications

(5 citation statements)

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“…11,27 The incidence of MDR in EPTB, taken together, varies from 4.3% to 22% in India, 19,28,29 12.5% in Nepal, 30 9.2% in Ethiopia, 18 and 21% in Pakistan. 31 The results of Rif and Inh susceptibility, as produced by MTBDRplus in the present study, were 100% concordant with both pDST and gene sequencing, thereby producing a sensitivity and specificity of 100% in detecting RifR and InhR. Because no prior study has evaluated MTBDR assay on GITB biopsy specimens earlier, a head-to-head comparison with currently available literature is not possible.…”

Section: Discussionsupporting

confidence: 56%

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MTBDRplus and MTBDRsl for simultaneous diagnosis of gastrointestinal tuberculosis and detection of first‐line and second‐line drug resistance

Sharma

et al. 2023

J of Gastro and Hepatol

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Background and Aim: Emergence of drug resistance, especially to second-line drugs, hampers tuberculosis elimination efforts. The present study aimed to evaluate MTBDRplus and MTBDRsl assays for detecting first-line and second-line drug resistance, respectively, in gastrointestinal tuberculosis (GITB). Methods: Thirty ileocecal biopsy specimens, processed in the Department of Microbiology between 2012 and 2022, that showed growth of Mycobacterium tuberculosis on culture were included in the study. DNA, extracted from culture, was subjected to MTBDRplus and MTBDRsl (Hain Lifescience GmbH, Nehren, Germany), following manufacturer's instructions. Their performance was compared against phenotypic drug susceptibility testing (pDST) and gene sequencing. Results: Out of the 30 specimens, 4 (13.33%) were mono-isoniazid resistant, 4 (13.33%) were multidrug resistant (MDR), 2 (6.67%) were pre-extensively drug resistant (pre-XDR), and 2 (6.67%) were mono-fluoroquinolone resistant. The results were 100% concordant with pDST and gene sequencing. Conclusions: In the wake of growing drug resistance in all forms of extrapulmonary tuberculosis, including GITB, MTBDRplus and MTBDRsl are reliable tools for screening of resistance to both first-line and second-line drugs.

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Section: Discussionsupporting

confidence: 56%

“…The incidence of MDR‐GITB is reported to range from 4% to 13.9% in India 11,27 . The incidence of MDR in EPTB, taken together, varies from 4.3% to 22% in India, 19,28,29 12.5% in Nepal, 30 9.2% in Ethiopia, 18 and 21% in Pakistan 31 …”

Section: Discussionmentioning

confidence: 99%

MTBDRplus and MTBDRsl for simultaneous diagnosis of gastrointestinal tuberculosis and detection of first‐line and second‐line drug resistance

Sharma

et al. 2023

J of Gastro and Hepatol

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“…The current diagnostic method of choice is echocardiography [6]. The characteristic findings that can be seen are a dilated right coronary artery (RCA), retrograde Doppler flow from the left coronary artery (LCA) to pulmonary artery (PA), and a septal flow due to collaterals [9]. However, there are reports of cases being missed on echocardiography just like our case.…”

Section: Discussionmentioning

confidence: 60%

Anomalous left coronary artery from pulmonary artery (ALCAPA) as a silent cause of mitral regurgitation in children

Ashraf

Zubairi

Atiq

et al. 2022

Monaldi Arch Chest Dis

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Anomalous left coronary artery from pulmonary artery (ALCAPA), also known as Bland-White-Garland syndrome, is a rare cardiac disease. This condition may present with complications such as myocardial infarction, left ventricular dilatation, mitral regurgitation, and left heart failure in children. We report a case of a four-year-old boy who presented with shortness of breath, palpitations, and recurrent upper respiratory tract infections. He was diagnosed with mitral regurgitation. During the surgery, left coronary artery (LCA) was not present in its anatomical position and ALCAPA was identified. One should keep in mind the possibility of ALCAPA in presentation of mitral regurgitation in children despite not being reported in echocardiography.

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“…A review of ALCAPA patients showed that 66% of adult patients presented with angina, dyspnea, palpitations or fatigue. Ventricular arrhythmias, syncope, or sudden death occurred in 17% of patients, while 14% remained asymptomatic [5].…”

Section: Discussionmentioning

confidence: 99%

Two cases of anomalous origin of left coronary artery from the pulmonary artery

Zhao¹,

Zou²

2022

J Clin Images Med Case Rep

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Coronary artery originating from pulmonary artery is a rare congenital vascular malformation, which generally presents corresponding clinical symptoms with the growth of patients’ age. Coronary CTA and angiography are important methods for diagnosis of this disease, and provide evidence for treatment strategies of patients. Keywords: bicardiovascular malformations; coronary arteries; coronary cta.

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Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA): a surgical certainty

Cited by 4 publications

References 0 publications

MTBDRplus and MTBDRsl for simultaneous diagnosis of gastrointestinal tuberculosis and detection of first‐line and second‐line drug resistance

MTBDRplus and MTBDRsl for simultaneous diagnosis of gastrointestinal tuberculosis and detection of first‐line and second‐line drug resistance

Anomalous left coronary artery from pulmonary artery (ALCAPA) as a silent cause of mitral regurgitation in children

Two cases of anomalous origin of left coronary artery from the pulmonary artery

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