Anomalous left coronary artery originating from the pulmonary artery. Report on 15 cases.

Askenazi, Joseph; Nadas, Alexanders .

doi:10.1161/01.cir.51.6.976

Cited by 135 publications

(33 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Simple ligation of the proximal main left coronary artery has been used with variable success. 5 [10][11][12][13] More recently, methods to establish a dual coronary system by reimplantation or construction of an intra-pulmonary artery baffle have been introduced.5 ' 12-17 Nonetheless, the capacity of the left ventricle for recovery after successful surgical repair of this lesion remains uncertain.…”

mentioning

confidence: 99%

Regional and global left ventricular function in infants with anomalous origin of the left coronary artery from the pulmonary trunk: preoperative and postoperative assessment.

Rein¹,

Colan²,

Parness³

et al. 1987

Circulation

View full text Add to dashboard Cite

Anomalous origin of the left coronary artery from the pulmonary trunk (ALCA) remains a diagnostic as well as a therapeutic problem. The purposes of this study were: (1) to analyze left ventricular mechanics, including regional wall motion, in infants with ALCA, (2) to determine if the pattern of wall motion in infants with ALCA distinguishes these patients from those with congestive cardiomyopathy of other causes, and (3) to evaluate the potential for recovery of left ventricular function after successful restoration of a dual coronary artery system. Left ventricular mechanics were studied before and serially after surgery in six infants (2 to 13 months old) with ALCA. Fifteen agematched normal subjects and seven age-matched patients with idiopathic congestive cardiomyopathy were also studied for comparison. Preoperatively, the end-diastolic volume in infants with ALCA was about four times larger than normal and did not differ from that in infants with CM; the myocardial volume was also about three times larger than normal, similar to that in the patients with CM. The myocardial volume/end-diastolic volume ratio was extremely low in patients with ALCA and in those with CM. The infants with ALCA did not exhibit specific segmental wall motion abnormalities but rather had global hypokinesis indistinguishable from that in the patients with CM. After successful repair, end-diastolic volume index rapidly decreased, reaching near normal values by 7 to 22 months after surgery, while myocardial volume index decreased at a slower rate, leading to an early phase of "overshoot hypertrophy," but reaching normal values by 7 to 22 months after surgery. The global and regional indexes of left ventricular function improved dramatically by 7 to 22 months after surgery, with the ejection fraction reaching the normal range and nine of the 13 left ventricular segments in short-and long-axis views exhibiting a normal shortening fraction. In conclusion (1) the regional wall motion pattern in infants with ALCA is not diagnostically useful for distinguishing ALCA from other causes of idiopathic congestive cardiomyopathy, (2) as in cardiomyopathy, preoperative left ventricular dysfunction in ALCA is severe and associated with inadequate left ventricular hypertrophy, (3) there is potential for nearly complete recovery of global and regional left ventricular function after successful repair of ALCA in early infancy. Circulation 75, No. 1, 115-123, 1987. ANOMALOUS ORIGIN of the left coronary artery from the pulmonary trunk (ALCA), although an uncommon lesion, remains a diagnostic and therapeutic problem. The diagnosis is difficult to confirm echocardiographically because of the unreliability of visualizing the origin of the coronary arteries.1`3 It has been proposed that left ventricular regional wall motion abFrom the Department of Cardiology, The Children's Hospital, Boston.

show abstract

mentioning

confidence: 99%

Regional and global left ventricular function in infants with anomalous origin of the left coronary artery from the pulmonary trunk: preoperative and postoperative assessment.

Rein¹,

Colan²,

Parness³

et al. 1987

Circulation

View full text Add to dashboard Cite

show abstract

“…As previously reported, about 60% -85% of affected patients die in the first two years of life because of myocardial infarction or congestive heart failure [2,3]. We present a rare case of BWG syndrome in an adult that sometimes led to severe myocardial ischemia, especially during exercise.…”

Section: Introductionmentioning

confidence: 61%

“…Frequent ECG findings include atrial fibrillation, left ventricular hypertrophy, abnormal Q waves, and/or negative T waves in leads aVL, Vs, and V6 [2]. However, because the ECG of some patients with BWG syndrome is almost normal, the above-mentioned findings are not helpful in differential diagnosis from other heart diseases [4][5][6].…”

Section: Discussionmentioning

confidence: 99%

An adult case of Bland-White-Garland syndrome with collaterals from the bronchial artery

et al. 1994

View full text Add to dashboard Cite

We report herein an adult case of anomalous origin of the left coronary artery from the pulmonary artery (Bland-White-Garland syndrome; BWG syndrome). The patient had chest discomfort during exercise and signs of mitral regurgitation. We diagnosed him as having BWG syndrome by angiography, and performed surgical treatment. At the operation, retrograde coronary blood flow was found through the left coronary artery during aortic cross-clamping. This suggested extracardiac anastomosis from peripheral arteries to the left coronary artery. Since the collateral blood flow was considerable during aortic cross-clamping, only the left coronary artery was closed. A collateral from the left bronchial artery to the left circumflex artery was demonstrated by postoperative angiography. Cases of adults with BWG syndrome are rare, and this may be the first report of a collateral from the bronchial artery.

show abstract

“…Este es el caso del síndrome de ALCAPA. Esta es una anomalía del origen del ostium de la ACI cuya incidencia se aproxima a 1/300.00 nacidos vivos y representa entre 0,26 y 0,46% de las cardiopatías congénitas 1,5 . En adultos tiene una incidencia no definida a nivel poblacional, en estudios angiográficos se describe una incidencia de 0,008% 6 (datos mostrados en el mayor registro angiográfico publicado hasta ahora, con más de 120.000 pacientes).…”

Section: Discussionunclassified

Síndrome de ALCAPA en adulto: Caso clínico

et al. 2017

Rev. méd. Chile

View full text Add to dashboard Cite

Anomalous left coronary artery originating from the pulmonary artery. Report on 15 cases.

Cited by 135 publications

References 17 publications

Regional and global left ventricular function in infants with anomalous origin of the left coronary artery from the pulmonary trunk: preoperative and postoperative assessment.

Regional and global left ventricular function in infants with anomalous origin of the left coronary artery from the pulmonary trunk: preoperative and postoperative assessment.

An adult case of Bland-White-Garland syndrome with collaterals from the bronchial artery

Síndrome de ALCAPA en adulto: Caso clínico

Contact Info

Product

Resources

About