Anomalies of the thoracic aorta: Pathologic considerations

Blieden, Leonard C.; Edwards, Jesse E.

doi:10.1016/0033-0620(73)90003-0

Cited by 8 publications

(2 citation statements)

References 23 publications

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“…Numerous aortic arch anomalies have been described. 2,3 Most of the time aberrant position of the supraaortic arteries reflects the isolation of a brachiocephalic artery. The development of mediastinal and thoracic great arteries is explained by embryological mechanisms and by the hypothetical double aortic arch of Knight and Edwards.…”

Section: Discussionmentioning

confidence: 99%

Isolated Left Common Carotid Artery Connected to the Pulmonary Artery

Fouilloux

Gran

Kreitmann

2013

World J Pediatr Congenit Heart Surg

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A three-year-old boy was referred for persistent arterial duct. Transthoracic echocardiography showed a right aortic arch and an unusual Doppler flow in the arch vessels and the pulmonary artery. The tomodensitometry showed a right-sided aortic arch, with successive origin of the right common carotid, the right subclavian artery, and an aberrant (lusoria) left subclavian artery. The left common carotid took origin from the pulmonary trunk. During surgery, a fibrous cord independent from the anomaly was identified. An end-to-side anastomosis between the left carotid and the ascending aorta was done and the fibrous cord was divided. Was this fibrous cord a ductal ligament?

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Section: Discussionmentioning

confidence: 99%

Isolated Left Common Carotid Artery Connected to the Pulmonary Artery

Fouilloux

Gran

Kreitmann

2013

World J Pediatr Congenit Heart Surg

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“…Of note is one case of a young woman who suffered from lupus erythematosus and died of myocardial infarction (Blieden, Tsackracklides and Edwards, 1973). At post-mortem, severe atherosclerotic changes were present.…”

Section: Acquired Conditionsmentioning

confidence: 99%

Coronary artery disease in children

Neufeld

Blieden

1978

Postgraduate Medical Journal

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SummaryIn this paper an attempt has been made to correlate the morphological aspects of childhood atherosclerosis. Some of the features described are directly related to atherosclerosis. Some of the other conditions described may be related to the subsequent development of atherosclerosis by damaging the vessel wall and thus stimulating the production of atherosclerosis. In other instances, as in the description of the ultrastructural features of the coronary arteries, the exact role of the changes described still remains to be elucidated.THE treatment of atherosclerosis in adulthood does not get to the root of the problem which is obviously prevention. The latter must of course start at an early age. In order to do this we must understand the aetiology and pathogenesis of atherosclerosis.It is the purpose in this paper to discuss the morphological features of childhood atherosclerosis. It is hoped that some of the features to be discussed will aid in the better understanding of this condition and thus of its prevention and treatment. The normal development of the coronary arteries and its influence on atherosclerosis will be briefly reviewed. Next to be considered will be the anatomical features in different ethnic groups and the possible effect of these differences on the prevalences ofatherosclerosis.The ultrastructural features of the coronary microcirculation will then be briefly described and an attempt be made to relate these features to subsequent pathological findings. Next, the effect of congenital heart lesions -especially those producing coronary hypertension -on the development of atherosclerosis will be considered. The coronary arterial changes in metabolic disorders will also be dealt with briefly.Finally, the end result of coronary artery diseasenamely myocardial infarction -in the childhood period will be considered. Normal coronary arteriesThe natural history of the development of coronary heart disease may be divided into three periods (Abramovici and Neufeld, 1965): The last period is the one with which we are all familiar. In the search for aetiological factors one must start in the infancy period and even back into fetal life. With this in mind the authors developed their studies of the histology of coronary arteries. Two main aspects were considered: the normal child, and the child with congenital heart disease. In the latter, an attempt was made to learn how the structural changes in the coronary arteries develop, particularly in those lesions where coronary artery hypertension exists, because of its possible implications in the development of atherosclerosis. Special emphasis has been placed in the studies on the differences in structural changes of coronary arteries in different ethnic groups.From the investigations performed up to the present, the histological changes which appear in the coronary arteries during the different stages of development in fetal life as well as after birth, have now been determined (Neufeld and Vlodaver, 1971).In fetuses, the intima is not developed, and co...

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Die Mißbildungen des Herzens und der großen Gefäße

Chuaqui¹,

Farru²

1993

Spezielle Pathologische Anatomie

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Anomalies of the thoracic aorta: Pathologic considerations

Cited by 8 publications

References 23 publications

Isolated Left Common Carotid Artery Connected to the Pulmonary Artery

Isolated Left Common Carotid Artery Connected to the Pulmonary Artery

Coronary artery disease in children

Die Mißbildungen des Herzens und der großen Gefäße

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