Anomalies et erreurs de détermination de l'hémogramme avec les automates d'hématologie cellulaire

Tessier-Marteau, Anne; Geneviève, Franck; Godon, Alban; Macchi, Laurent; Zandecki, Marc

doi:10.1684/abc.2010.0451

Cited by 7 publications

(4 citation statements)

References 43 publications

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“…Therefore, nonplatelet elements similar in size to platelets may result in inaccurate counting . Thus, a significant increase in the platelet count in samples with a high degree of hemolysis is justified by the fact that this count is affected by the presence of RBC fragments …”

Section: Discussionmentioning

confidence: 99%

“…19 Thus, a significant increase in the platelet count in samples with a high degree F I G U R E 4 Bland-Altman graphs for platelet counts: concordance analysis between samples without hemolysis and HD < 5% (A); without hemolysis and HD > 5% (B) of hemolysis is justified by the fact that this count is affected by the presence of RBC fragments. 20 The main difference of this study was evaluating hemolyzed samples in the impedance-based hematology analyzer. The results of this study showed different results when compared with other methodology, as the flow cytometry method.…”

Section: Discussionmentioning

confidence: 99%

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Interference of in vitro hemolysis complete blood count

Jonge

Santos

Cruz

et al. 2018

Clinical Laboratory Analysis

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Interference of in vitro hemolysis complete blood count

Jonge

Santos

Cruz

et al. 2018

Clinical Laboratory Analysis

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“…The presence of cryofibrinogen and the involvement of thrombospondin [80,85] could also be encountered in this phenomenon. As such, probably, platelets adhere to the PMN membrane and then detach over time as platelet clumps [42,86].…”

Section: Platelet Clumpsmentioning

confidence: 99%

Platelet Counting: Ugly Traps and Good Advice. Proposals from the French-Speaking Cellular Hematology Group (GFHC)

Baccini

Geneviève

Jacqmin

et al. 2020

JCM

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Despite the ongoing development of automated hematology analyzers to optimize complete blood count results, platelet count still suffers from pre-analytical or analytical pitfalls, including EDTA-induced pseudothrombocytopenia. Although most of these interferences are widely known, laboratory practices remain highly heterogeneous. In order to harmonize and standardize cellular hematology practices, the French-speaking Cellular Hematology Group (GFHC) wants to focus on interferences that could affect the platelet count and to detail the verification steps with minimal recommendations, taking into account the different technologies employed nowadays. The conclusions of the GFHC presented here met with a "strong professional agreement" and are explained with their rationale to define the course of actions, in case thrombocytopenia or thrombocytosis is detected. They are proposed as minimum recommendations to be used by each specialist in laboratory medicine who remains free to use more restrictive guidelines based on the patient's condition.

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“…It is well known that ethylenediaminetetraacetic acid (EDTA) can cause in vitro agglutination of various blood cell types (most of the time platelets and less frequently neutrophils). 4 The involvement of lymphocytes is very unusual as the frequency of this phenomenon has been estimated at less than one case out of 45 000 blood cell counts. 5 Nevertheless, when it occurs, it usually is in a context of Bcell chronic lymphoproliferative disorder, comprising MZL.…”

Section: Introductionmentioning

confidence: 99%