Infections of the genitals, including infections caused by the human papillomavirus (HPV) are still quite common in Indonesia country. The general population that is often found in this case is HPV 16 and 18. Condyloma acuminata (CA) is an infection of HPV in the vaginal region that causes a cauliflower-like benign tumor. Infection is one of the causes of morbidity and mortality in individuals with systemic lupus erythematosus (SLE), and this illness might increase the risk of human papillomavirus (HPV) infection, particularly condyloma acuminatum.