Annular Pustular Psoriasis

Adler, Donald J.

doi:10.1001/archderm.1981.01650050069029

Cited by 12 publications

(17 citation statements)

References 2 publications

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“…Nearly 60% (78 patients) had annular lesions, of which 78% (61 patients) had solely APP and 22% (17 patients) had a mixture of generalized pustular psoriasis (GPP) and APP. Adler et al (3) described APP as gyrate, annular lesions with an erythematous, scaly, and pustular margin. Like GPP, fever and leukocytosis may accompany the onset of pustules; however, APP has a more benign course (3) and can be intermittent over years.…”

Section: Discussionmentioning

confidence: 99%

“…Adler et al (3) described APP as gyrate, annular lesions with an erythematous, scaly, and pustular margin. Like GPP, fever and leukocytosis may accompany the onset of pustules; however, APP has a more benign course (3) and can be intermittent over years. The recurrent, annular plaques are characterized by an erythematous, scaly, pustular margin that desquamates within 24 hours (1,3).…”

Section: Discussionmentioning

confidence: 99%

“…The major histologic features shared by APP and typical plaque‐type psoriasis include confluent parakeratosis, acanthotic epidermis with regular elongation of rete ridges, focal epidermal edema, epidermal spongiform pustules, dilatation of superficial dermal capillaries, and an infiltrate of mononuclear cells and neutrophils in the upper dermis (1,3,8). These histologic features were observed in both patients.…”

Section: Discussionmentioning

confidence: 99%

“…Annular pustular psoriasis (APP) is a well‐documented form of psoriasis characterized by primary annular erythematous pustule‐studded plaques often occurring on the trunk, neck, and extremities. Although pustular psoriasis is rare in children, they are more likely to manifest annular lesions than adults (1–4). Primary, plaque‐type, exclusively annular psoriasis has not been previously described, and we herein present two women who developed these lesions during adolescence.…”

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confidence: 99%

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Primary Annular Plaque‐Type Psoriasis

Guill¹,

Hoang

Carder³

2005

Pediatric Dermatology

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We described two adolescent girls with untreated, consistently annular, plaque-type psoriasis without pustules, a presentation that is to our knowledge, not previously described. No typical confluent plaque-type lesions were present. The plaques in our patients resembled other entities such as tinea corporis and erythema annulare centrifugum, given the erythematous, scaling borders and central clearing. Biopsy specimens from our patients showed features characteristic of psoriasis vulgaris. Both patients responded to combination therapy with calcipotriene and a mid-potency steroid. We conclude that primary annular plaque-type psoriasis shares features of both typical plaque-type and annular pustular psoriasis, suggesting that these entities represent a spectrum of psoriatic disease.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

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Primary Annular Plaque‐Type Psoriasis

Guill¹,

Hoang

Carder³

2005

Pediatric Dermatology

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“…Diagnosis of EACP, also called annular pustular psoriasis or annular centrifugal psoriasis type Lapiere, 4,8,9 can be difficult. The ring‐form or serpiginous erythemas, variably with pustulation, scabby or colerette‐like scaling, have to be differentiated from subcorneal pustular dermatosis of Sneddon and Wilkinson, Sweet's syndrome, necrolytic migratory erythema and the annular and gyrate erythemas; but tinea corporis, pityriasis rosea, pemphigus foliaceus, dermatitis herpetiformis or a form of the variable erythrokeratodermias may also come into question 4–12 …”

Section: Discussionmentioning

confidence: 99%

Erythema annulare centrifugum‐type psoriasis: a particular variant of acute‐eruptive psoriasis

Vocks

Ring

2003

Acad Dermatol Venereol

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A case of erythema annulare centrifugum-type psoriasis in a 58-year-old white woman with a history of chronic plaque psoriasis is described. Initial failure of antipsoriatic treatments and an untypical histology complicated the diagnosis. After several trials acitretin at a low maintenance dose combined with oral fish oil and topical calcitriol led to sustained long-term remission. The spectrum of clinical differentiation of this rare disease, the histological characteristics and its nosological classification are discussed. It is suggested that this dermatosis represents a variant of acute psoriasis, rather than a variant of pustular psoriasis.

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Clinical Course and Characteristics of Generalized Pustular Psoriasis

2022

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Generalized pustular psoriasis (GPP) is a rare, potentially life-threatening disease characterized by episodes of widespread sterile macroscopic pustules, with or without systemic inflammation and/or plaque psoriasis. Multiple GPP subtypes have been described, from acute GPP of von Zumbusch to milder, annular pustular psoriasis. Generalized pustular psoriasis mainly affects adults, with a female preponderance, but juvenile GPP also occurs. Flares are a hallmark of GPP and may occur de novo or be provoked by triggers, including withdrawal of systemic corticosteroids, infections, stress, pregnancy, and menstruation. Severity of flares varies widely between patients, and between flares in an individual patient. Significant flares are often accompanied by systemic symptoms, notably fever, general malaise, and extracutaneous manifestations such as arthritis, uveitis, and neutrophilic cholangitis. Common laboratory abnormalities include neutrophilia, elevated C-reactive protein levels, hypocalcemia, and abnormal liver function tests. The clinical course of GPP is highly variable; it can be a relapsing disease with recurrent flares and no pustulation between flares or a persistent disease with perpetual mild pustulation punctuated with flares of greater severity. Patients may have multiple flares per year or a flare every few years. Most flares last 2–5 weeks and approximately 50% require hospitalization. Life-threatening complications include sepsis and renal, hepatic, respiratory, and heart failure. Reported mortality rates are 2–16%.

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Annular Pustular Psoriasis

Cited by 12 publications

References 2 publications

Primary Annular Plaque‐Type Psoriasis

Primary Annular Plaque‐Type Psoriasis

Erythema annulare centrifugum‐type psoriasis: a particular variant of acute‐eruptive psoriasis

Clinical Course and Characteristics of Generalized Pustular Psoriasis

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