Annular pancreas in China: 9 years’ experience from a single center

Abstract

To summarize the clinical characteristics, diagnosis, treatment and prognosis among 152 children with annular pancreas (AP). A retrospective review of 152 patients with AP who were treated with surgical repair between January 2009 and August 2017 was performed at our pediatric surgical units. Presenting symptoms, birth weight, radiological findings, associated anomalies, the type of surgery performed were analyzed. (1) 152 patients were identified, out of which 82 were males, and 70 were females; (2) the average birth weight of children with AP was less than that of healthy newborns. The birth weights of 5.4% premature infants were less than 1500 g; the birth weight of 17% full-term infants, 69% premature infants and 50% post-term infants were less than 2500 g. (3) 100 (66%) patients presented symptoms during neonatal period and 43 (28%) patients had duodenal obstruction diagnosed by prenatal ultrasound scan. (4) All cases were managed surgically by open laparotomy, and all patients were duly discharged. AP most commonly presents symptoms in early neonatal period. Infants with AP are associated with a higher rate of low birth weight, and it was because swallowed amniotic fluid could not be absorbed and impaired insulin secretion caused by abnormal pancreas. Ultrasonography, abdominal plain film and upper gastrointestinal series (UGI) are helpful, but cannot make the diagnosis, and surgery is the only effective way to diagnose and treat AP.

Annular Pancreas in Neonates; Case Series and Review of Literatures

“…stated that the association of annular pancreas and low birth weight could be due to the failure of amniotic fluid absorption in the gastrointestinal tract in addition to pancreatic insulin secretion impairment. [ 18 ] Down syndrome was diagnosed in one case (16.7%), while Yigiter et al . reported that 8 of 22 (36.3%) patients had trisomy 21.…”

Annular pancreas: Radiological features of a rare case of infantile vomiting

“…Annular pancreas is a rare congenital abnormality defined by a ring of cephalic pancreatic tissue partially or completely surrounding the second part of the duodenum [1] , [2] , [3] .…”

Investigation of annular pancreas through multiple detector spiral CT (MDCT) and MRI

“…A literature review has revealed that annular pancreas has scarcely been reported, with few large sample systematic studies. 10 In order to improve understanding of this disease and provide help for clinics, we retrospectively analyzed the clinical and imaging data of 24 cases of annular pancreas, investigated the imaging features of annular pancreas in adults, and found the best sequence for diagnosis of annular pancreas.…”