Annular leucocytoclastic vasculitis: response to dapsone

Ruiz‐Villaverde, Ricardo; Melguizo, J. Blasco; Sánchez, MC Martín; Sintes, R. Naranjo

doi:10.1046/j.1468-3083.2002.00559_10.x

Cited by 22 publications

(16 citation statements)

References 8 publications

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“…Tamoxifen [24], anastrozole [25], etoposide [26], erlotinib [27], and capecitabine [28] are agents that have been implicated in the literature. Again, subclinical infections suffered by these patients based on immunosuppression may also cause vasculitis [29, 30].…”

Section: Discussionmentioning

confidence: 99%

Demographic characteristics, aetiology, and assessment of treatment options in leukocytoclastic vasculitis

Çakıter¹,

Küçük²,

Özkaya³

et al. 2017

pdia

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IntroductionVasculitides are a heterogeneous group of diseases characterized by inflammation of the blood vessel walls. Etiological factors include infections, drugs, connective tissue diseases, and malignancies.AimTo examine the demographic characteristics, etiological factors, and treatment options in 75 patients with leukocytoclastic vasculitis.Material and methodsThe study included 75 patients diagnosed with leukocytoclastic vasculitis at our clinic. The patients’ medical records were reviewed to determine their age, sex, presence of systemic symptoms, possible etiological factors, laboratory results, types of cutaneous lesions, locations of the lesions, treatment options, and disease course.ResultsThere were 43 women and 32 men. Cutaneous lesions affected only the lower limbs in 60 of the 75 patients (80%) and usually presented as palpable purpura (64%, n = 48). Arthralgia (26.7%, n = 20) was the most frequent extracutaneous symptom. Of the patients with secondary vasculitis, the most common causes were infections and drugs. The mean age of the patients with Henoch-Schönlein purpura was 26.8 years. There was no significant association between age and renal, gastrointestinal, or joint involvement.ConclusionsThe most common form of vasculitis in our study was cutaneous leukocytoclastic vasculitis. In most of the patients it appeared to be idiopathic. Among drugs, antibiotics were the most common etiological factor. In 4 patients, the cutaneous leukocytoclastic vasculitis behaved like the paraneoplastic syndrome.

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Section: Discussionmentioning

confidence: 99%

Demographic characteristics, aetiology, and assessment of treatment options in leukocytoclastic vasculitis

Çakıter¹,

Küçük²,

Özkaya³

et al. 2017

pdia

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“…Dapsone is primarily an anti‐inflammatory medication with a predominantly antineutrophilic effect that is frequently used in various vasculitic diseases and neutrophilic dermatoses, such as Sweet's syndrome (SS), erythema elevatum diutinum (EED), pyoderma gangrenosum (PG), dermatitis herpetiformis (DH), and HSP 34 . A few cases have shown complete resolution in cutaneous LCV and refractory HUV with doses of 100–200 mg daily 35–37 . Although directly reported cases are few in the literature, dapsone is considered a frequent treatment modality in many vasculitis reviews 6,7,11 .…”

Section: Treatmentmentioning

confidence: 99%

Primary cutaneous small vessel vasculitis: approach to diagnosis and treatment

2006

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“…In our case, only the combination of lamivudine to treat the hepatitis and dapsone 200 mg/day successfully ameliorated the clinical occurrence of the annular leucocytoclastic vasculitis and provoked a long‐lasting remission 8 …”

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confidence: 62%