2011
DOI: 10.2310/7750.2011.10042
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Annular Elastolytic Giant Cell Granuloma Associated with Temporal Arteritis Leading to Blindness

Abstract: There have been only two previous case reports presenting an association between AEGCG and temporal arteritis. This report explores AEGCG and its possible relationship to temporal arteritis along with possible treatment regimens cited in the current literature.

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Cited by 14 publications
(17 citation statements)
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“…53 An association between EAGCG and temporal arteritis has been documented, suggesting a common cause of both conditions. 54,55 A similar inflammatory reaction is observed in AG and temporal arteritis. Actinic radiation may injure the elastic tissue not only of the skin but also of superficial arteries, damaging the elastic lamina and becoming antigenic.…”
Section: Systemic Associationssupporting
confidence: 67%
“…53 An association between EAGCG and temporal arteritis has been documented, suggesting a common cause of both conditions. 54,55 A similar inflammatory reaction is observed in AG and temporal arteritis. Actinic radiation may injure the elastic tissue not only of the skin but also of superficial arteries, damaging the elastic lamina and becoming antigenic.…”
Section: Systemic Associationssupporting
confidence: 67%
“…The underlying basis of this association is thought to be related to actinic degeneration of elastic tissue not only of the skin, but also of the internal elastic lamina of vessels (Gutierrez-Gonzalez et al, 2013, O'Brien and Regan, 1999). Since then, few reports in the literature have demonstrated the association between actinic granuloma and temporal arteritis (Lau et al, 1997, Shoimer and Wismer, 2011); interestingly, all cases demonstrating the association have occurred in males, despite the higher prevalence of actinic granuloma in females. Our case supports this rarely discussed, yet serious, complication.…”
Section: Discussionmentioning
confidence: 99%
“…Lau et al (1997) described two elderly gentlemen who presented with solitary lesions on the forehead, and Shoimer and Wismer (2011) described an elderly gentleman who presented with erythematous annular confluent plaques in predominantly sun-exposed locations. Our case further supports the possibility of temporal arteritis in a variety of presentations of actinic granuloma.…”
Section: Discussionmentioning
confidence: 99%
“…Most of the patients are middle-aged, white women. The lesions are generally asymptomatic and heal without scarring (1,(3)(4)(5).…”
Section: Discussionmentioning
confidence: 99%