Annual FEV1 Loss in Patients with Noncystic Fibrosis Bronchiectasis and Affecting Factors

Börekçi, Şermin; Gundogdu, Şule; Harbiyeli, Deniz Öngel; Müsellim, Benan

doi:10.14423/smj.0000000000001394

Cited by 2 publications

(1 citation statement)

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“…Rapid lung function decline is an important pathophysiology leading to COPD. However, changes in lung function in bronchiectasis vary widely across studies ( Figure 2 ) [ 20 - 25 ].…”

Section: Controversial Issues 1: Bronchiectasis With Airflow Limitationmentioning

confidence: 99%

Proposed Etiotypes for Chronic Obstructive Pulmonary Disease: Controversial Issues

Kim,

Moon,

Min

et al. 2024

Tuberc Respir Dis

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The 2023 Global Initiative for Chronic Obstructive Lung Disease (GOLD) revised the definition of chronic obstructive pulmonary disease (COPD) to broadly include a variety of etiologies. A new taxonomy, composed of etiotypes, aims to highlight the heterogeneity in causes and pathogenesis of COPD, allowing more personalized management strategies and emphasizing the need for targeted research to understand and manage COPD better. However, controversy arises with including some diseases under the umbrella term of COPD, as their clinical presentations and treatments differ from classical COPD, which is smoking-related. COPD due to infection (COPD-I) and COPD due to environmental exposure (COPD-P) are classifications within the new taxonomy. Some disease entities in these categories show distinct clinical features and may not benefit from conventional COPD treatments, raising questions about their classification as COPD subtypes. There is also controversy regarding whether bronchiectasis with airflow limitations should be classified as an etiotype of COPD. This article discusses controversial issues associated with the proposed etiotypes for COPD in terms of COPD-I, Controversial Issues 1: Bronchiectasis with Airflow LimitationBronchiectasis is a disease entity of clinical and radio-COPD-P, and bronchiectasis. While the updated COPD definition by GOLD 2023 is a major step towards recognizing the disease's complexity, it also raises questions about the classification of related respiratory conditions. This highlights the need for further research to improve our understanding and approach to COPD management.

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“…Rapid lung function decline is an important pathophysiology leading to COPD. However, changes in lung function in bronchiectasis vary widely across studies ( Figure 2 ) [ 20 - 25 ].…”

Section: Controversial Issues 1: Bronchiectasis With Airflow Limitationmentioning

confidence: 99%