Annona squamosa: Phytochemical Constituents, Bioactive Compounds, Traditional and Medicinal Uses

Ahmed, Rasheeda Hamid Abdalla; Mariod, Abdalbasit Adam

doi:10.1007/978-3-030-31885-7_12

Cited by 3 publications

(4 citation statements)

References 39 publications

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“…This Annona species remains one of the most researched in the world and is well known for having antidiabetic effects [58]. It has a variety of pharmacological characteristics, primarily antitumor properties, in its seeds, bark, and leaves [59].…”

Section: Annona Squamosa (Sugar Apple/sweetsop)mentioning

confidence: 99%

Chemopreventive Potential of Oils Extracted from Seeds of Three Annona Species

Attanayake,

Rupasinghe,

Gamage

et al. 2024

Seeds

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Annona fruit, leaves, seeds, roots, and bark have been conventionally used in many countries for medical treatments as they are considered ideal sources of pharmacologically active compounds, but Annona remains an underutilized fruit in many countries. The fruit of these plants is delicately flavored and is used in industrial products such as ready-to-serve beverages, wine, jellies, jam, and fruit-butter preserve, while the seeds generally go to waste. Annona seed oil contains numerous health-benefiting factors such as vitamins, minerals, bioactive compounds, fatty acids, antioxidants, and phenolic compounds, which are responsible for various biological activities, including antibacterial, antioxidant, and antitumor activities. Cancer is a worldwide major health problem that remains unresolved. Even though the current treatments can manage to reduce tumor growth, there is an urgent need to investigate more efficient but less expensive novel techniques to overcome some of the restrictions in treating tumors. Annona might offer an indispensable choice besides chemotherapy and radiotherapy, especially for terminally ill patients, as the Annona genus contains secondary metabolites in nearly every component of Annona plants. Research has shown that many Annona species contain promising components that could potentially exhibit anticancer activity, but the information available is scarce and inconsistent. Annona muricata (Soursop, “Katuanoda”), Annona squamosa (Sweetsop, “Seenianoda”), and Annona reticulata (Custard apple, “Welianoda”) are three commonly cultivated edible Annona species in Sri Lanka. The main objective of the review was to present an updated comprehensive literature analysis of the putative chemopreventive functions against cancer cell lines/the anticancer effect on cancers, phytochemical properties, and antioxidant properties possessed by the seed oils of three selected common Annona species. Although there are some in vitro and in vivo experimental investigations supporting the benefits of Annona seed oils, clinical investigations are still needed to explore concealed areas, determine the effects on the human body, determine the safest concentration, and determine health-contributing benefits before they are submitted to clinical trials.

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Section: Annona Squamosa (Sugar Apple/sweetsop)mentioning

confidence: 99%

Chemopreventive Potential of Oils Extracted from Seeds of Three Annona Species

Attanayake,

Rupasinghe,

Gamage

et al. 2024

Seeds

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“…In the Aligarh district village in Uttar Pradesh, A. squamosa is well-known for its antidiabetic properties [ 63 ]. Its seeds, bark and leaves possess various pharmacological properties, mainly anti-tumour properties [ 64 ].…”

Section: Annona Generamentioning

confidence: 99%

Traditional Uses, Phytochemistry and Pharmacological Activities of Annonacae

2022

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In 1789, the Annonaceae family was catalogued by de Jussieu. It encompasses tropical and subtropical plants which are widespread in distribution across various continents such as Asia, South and Central America, Australia and Africa. The genus of Annona is one of 120 genera of the Annonaceae family and contains more than 119 species of trees and shrubs. Most species are found in tropical America, where over 105 species have been identified. Due to its edible fruits and medicinal properties, Annona is the most studied genus of Annonaceae family. To date, only a limited number of these species have economic value, including A. squamosa L. (sugar apple), A. cherimola Mill. (Cherimoya), A. muricata L. (guanabana or soursop), A. atemoya Mabb. (atemoya), a hybrid between A. cherimola and A. squamosa, A. reticulata L. (custard apple), A. glabra L. (pond-apple) and A. macroprophyllata Donn. Sm. (ilama). Phytochemically, several classes of secondary metabolites, including acetogenins, essential oils, alkaloids, terpenoids and flavonoids. The pharmacological activities of Annona species leaves and seeds include antibacterial, anticancer, antidiabetic and anti-inflammatory properties.

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“…However, custard apple seeds are rich in oil, with a yield of around 24%–28% (w/w) and a composition of mainly oleic and linoleic acid. Therefore, the use of custard apple seed oil as a source of bio‐based plasticizers can provide a sustainable solution for reducing waste and utilizing renewable resources 22,16,17,20 …”

Section: Introductionmentioning

confidence: 99%

“…Therefore, the use of custard apple seed oil as a source of bio-based plasticizers can provide a sustainable solution for reducing waste and utilizing renewable resources. 22,16,17,20 The main goal of this project is to find sustainable alternatives to plasticizers for PVC compounds. These alternatives should be derived from renewable sources, that is, custard apple seed oil.…”

Section: Introductionmentioning

confidence: 99%

Synthesis of bio‐based plasticizer from custard apple seed oil for PVC application

Kharat,

2024

Vietnam Journal of Chemistry

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In the research, a bio‐based through epoxidizing, plasticizer was created non‐toxic custard apple seed oil (CASO) using peroxy acid generated in situ and investigates the application of a bio‐based plasticizer in the compounding of polyvinyl chloride as epoxidized custard apple seed oil (ECASO) (PVC). The ECASO was synthesized through an epoxidation reaction and characterized using Fourier‐transform infrared spectroscopy and analytical parameters such as epoxy value, and oxirane conversion. To create plasticized PVC, the PVC was mixed with different ratios of ECASO and dioctyl phthalate (DOP) using a two‐roll mill and prepared PVC sheet by compression molding. The ECASO plasticizer completely fuses with PVC and plasticized PVC sheets are made. Glass transition temperature, tensile strength, percent elongation, solvent resistance, differential scanning calorimetry (DSC), and thermal gravimetric analysis were among the mechanical and thermal characteristics of PVC sheets that were assessed. This result shows the plasticization efficiency of ECASO and DOP combined was similar to that of DOP alone, even with the same plasticizer loading. Moreover, when used in combination with DOP, ECASO was found to be a more efficient plasticizer. As a result, ECASO can be used as a biobased substitute for DOP, replacing up to 60% of the ECASO plasticizer loading.

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Annona squamosa: Phytochemical Constituents, Bioactive Compounds, Traditional and Medicinal Uses

Cited by 3 publications

References 39 publications

Chemopreventive Potential of Oils Extracted from Seeds of Three Annona Species

Chemopreventive Potential of Oils Extracted from Seeds of Three Annona Species

Traditional Uses, Phytochemistry and Pharmacological Activities of Annonacae

Synthesis of bio‐based plasticizer from custard apple seed oil for PVC application

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