Ankylosing spondylitis and non-radiographic axial spondyloarthritis: Two stages of disease?

Rumyantseva, D. G.; Dubinina, Tatiana V.; Demina, A.; Rumyantseva, O.; Agafonova, E.; Смирнов, А. В.; Эрдес, Ш. Ф.

doi:10.17116/terarkh201789533-37

Cited by 18 publications

(8 citation statements)

References 18 publications

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“…In this study, extra‐articular involvement rates except for IBD ( P = .053), HLA‐B27 status and fulfillment of the ASAS criteria were not different in radiographic and non‐radiographic groups. Similar to our results, in a study to compare the clinical manifestations of AS and nr‐axSpA, the patients in the 2 groups did not differ in the presence of arthritis and enthesitis, disease activity (BASDAI, ASDAS‐CRP) and functional status (BASFI) and unlike our results, uveitis in AS patients were reported to be more prevalent in a meta‐analysis . In another retrospective study, patients with AS were more often men and had longer symptom duration.…”

Section: Discussionsupporting

confidence: 87%

Ultrasonographic evaluation of Achilles tendon: Is there any difference between ankylosing spondylitis, non‐radiographic axial spondyloarthropathy and controls?

et al. 2020

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Purpose:The aim is to evaluate Achilles tendon enthesopathy with ultrasound (US) in ankylosing spondylitis (AS) and non-radiographic axial SpA (nr-axSpA) patients and controls, and compare these groups in terms of associations between disease activity parameters and ultrasonographic Achilles enthesitis signs. Methods:A total of 24 AS and 20 nr-axSpA patients fulfilling the Assessment in Spondyloarthritis International Working Group criteria for axSpA and 30 controls were enrolled. Demographic characteristics, erythrocyte sedimentation rate, C-reactive protein (CRP), human leukocyte antigen (HLA)-B27, Bath AS Disease Activity Index, Bath AS Functional Index, Bath AS Metrology Index, Maastricht AS Enthesitis Score (MASES), AS Disease Activity Score-CRP, modified Stoke AS Spine Score (m-SASSS) scores and ultrasonographic findings were noted. Results: HLA-B27 positivity, extra-articular and peripheral involvement, disease activity, functional status, mean m-SASSS, ultrasonographic gray scale (GS) andtotal scores were similar between AS and nr-axSpA groups. In GS, tendon echotexture scores were significantly different across all groups (0.812 ± 0.384 in AS, 0.575 ± 0.466 in nr-axSpA, 0.017 ± 0.091 in controls; P < .001). Entheseal calcification scores were similar in AS and nr-axSpA patients, and higher than controls (P = .001).Bone profile scores were similar in patients with AS and nr-axSpA, and higher than controls (P = .010). When the correlations between US findings and disease activity and functional status were considered, power Doppler US (PDUS) and MASES total scores were positively correlated in the AS group (P = .045; r = .41). Conclusion: AS and nr-axSpA patients were found to be similar in various clinical, functional, and US findings indicating that these 2 entities are different phenotypic reflections of the same disease spectrum. The positive correlation between PDUS and MASES scores in AS patients substantiate the performance of MASES in evaluation of entheseal activity. K E Y W O R D S achilles, ankylosing spondylitis, enthesitis, non-radiographic axial spondyloarthritis, ultrasound

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Section: Discussionsupporting

confidence: 87%

Ultrasonographic evaluation of Achilles tendon: Is there any difference between ankylosing spondylitis, non‐radiographic axial spondyloarthropathy and controls?

et al. 2020

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“…Axial spondyloarthritis (axSpA) includes non-radiological axSpA (nraxSpA) and radiological axSpA (namely, AS). Since patients with nraxSpA have similar clinical characteristics to those with confirmed AS, Rumyantseva et al proposed that the former can be imagined as the early stage of AS (33). Due to different clinical manifestations and limited knowledge among general practitioners (GPs), axSpA is often diagnosed with a delay (34), which may lead to a more severe prognosis.…”

Section: Discussionmentioning

confidence: 99%

Research hotspots and trends analysis of ankylosing spondylitis: a bibliometric and scientometric analysis from 2009 to 2018

Liang¹,

Meng²,

Zhou³

et al. 2020

Ann Transl Med

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Background: This study utilized bibliometric analysis to qualitatively and quantitatively analyze hotspots and predict trends in the field of ankylosing spondylitis (AS) research.Methods: Articles about AS were obtained from the Web of Science Core Collection and PubMed database, and bibliometric analysis was carried out through CiteSpace and the Online Analysis Platform of Literature Metrology and Bibliographic Item Co-Occurrence Matrix Builder (BICOMB). Then, co-word biclustering analysis was conducted to obtain research hotspots and predict trends using gCLUTO software. Results: A total of 6,818 articles on AS from 2009 to 2018 were analyzed, showing an increasing publication trend (558 articles in 2009 to 851 articles in 2018). The Journal of Rheumatology was the leading journal in AS research, with an impact factor (IF) of 3.634 and H-index value of 49. In terms of region, the United States led the world in this field, and The University of Toronto was the leading institution for AS research. Van Der Heijde, D was the most prolific author in the field. Eight research hotspots in the field of AS were also identified.Conclusions: Our analysis identified eight research hotspots, and predicted that surgical treatment and etiology will be the main AS research trends in the future. This study provides new directions and ideas for future research in AS.

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“…Во-первых, дебют аксСпА приходится на молодой, трудоспособный возраст [5][6][7][8][9], когда ввиду активной тру-довой занятости у человека нет времени посещать врачей для регулярного наблюдения за состоянием здоровья. Во-вторых, укомплектованность медицинских учреждений врачами ревматологами в настоящее время не удовлетворя-ет растущим потребностям населения, особенно на уровне первичного звена.…”

Section: Draft «Aspine» Mobile Application For Patients With Early Axunclassified

Draft «aspine» Mobile Application for Patients With Early Axial Spondyloarthritis

Румянцева¹,

Dubinina²,

Эрдес³

2017

rsp

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Ankylosing spondylitis and non-radiographic axial spondyloarthritis: Two stages of disease?

Abstract: Due to the fact that the clinical manifestations of AS and nrAxSpA are comparable, it can be assumed that the latter is an early stage of AS.

Cited by 18 publications

References 18 publications

Ultrasonographic evaluation of Achilles tendon: Is there any difference between ankylosing spondylitis, non‐radiographic axial spondyloarthropathy and controls?

Ultrasonographic evaluation of Achilles tendon: Is there any difference between ankylosing spondylitis, non‐radiographic axial spondyloarthropathy and controls?

Research hotspots and trends analysis of ankylosing spondylitis: a bibliometric and scientometric analysis from 2009 to 2018

Draft «aspine» Mobile Application for Patients With Early Axial Spondyloarthritis

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