“…Risk factors for infection after open reduction and internal fixation of ankle fractures include diabetes mellitus [2,4,7,8,12,13,15,18], alcoholism [20], advanced age [1], and high-energy injuries [9]. Patients with diabetes mellitus after operative treatment of ankle fractures have had infection rates ranging from 10% to 60% [7,13], amputation rates up to 42% in open ankle fractures [21], and mortality up to 11% [18].…”