Anisometropic amblyopia: Axial length versus corneal curvature in children with severe refractive imbalance

Patel, Vaidehi S.; Simon, John W.; Schultze, R.

doi:10.1016/j.jaapos.2010.07.008

Cited by 19 publications

(20 citation statements)

References 6 publications

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“…This is further evidence that hyperopia in anisometropic amblyopia is primarily axial in nature, as is the case for hyperopia in general. 3 The authors of previous biometric studies of amblyopia agree with this observation, 8,13,14 although exceptions can occur. For example, in the current study, 2 of the 9 patients without anisometropia had interocular axial length difference of greater than 0.20 mm (patients 3 and 8 in e-Supplement 1).…”

Section: Volume 16 Number 1 / February 2012 Khansupporting

confidence: 61%

The relationship of axial length to cycloplegic refraction and keratometry in amblyopic eyes of hyperopic children

Khan

2012

Journal of American Association for Pediatric Ophthalmology and

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Section: Volume 16 Number 1 / February 2012 Khansupporting

confidence: 61%

The relationship of axial length to cycloplegic refraction and keratometry in amblyopic eyes of hyperopic children

Khan

2012

Journal of American Association for Pediatric Ophthalmology and

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“…One of these reports studied a population with a broad age-range that included some individuals with mature eyeballs and others with immature eyeballs [11]. The low ages of subjects in that and another study may have skewed the results, as the eyeballs of those subjects are still in the process of enlarging [11,12]. In contrast, the population used in this study was composed of subjects with mature eyeballs and a more homogenous sample in general.…”

Section: Discussionmentioning

confidence: 99%

The Correlation of Differences in the Ocular Component Values with the Degree of Myopic Anisometropia

Kim

Cho

Yang

et al. 2013

Korean J Ophthalmol

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PurposeTo determine the relationship between the differences in the ocular component values with the degree of anisomyopia.MethodsRefraction, corneal power (CP), and biometry were examined in 50 myopic adults with refractive differences (RD) over 1.50 diopters (D). Ocular components were measured by ultrasound biometry and keratometry. The correlation between the differences in the ocular component values with the degree of anisomyopia was analyzed by linear regression analysis.ResultsAmong 50 adults with anisomyopia, 5 had RD from 1.50 to 2.99 D, 11 had RD from 3.00 to 3.99 D, 9 had RD from 4.00 to 5.99 D, 12 had RD from 6.00 to 7.99 D, 7 had RD from 8.00 to 11.99 D, and 6 had ≥12.00 D. There was no significant correlation between the ocular components (CP, crystalline lens thickness [LT], and anterior chamber depth [ACD], and the length from the cornea to the posterior surface of the lens [ACD + LT]) and the RD (p > 0.05). The RD showed a significantly positive correlation with vitreous chamber depth (VCD), and axial length (r = 0.963, p < 0.0001).ConclusionsThe severity of anisomyopia was not correlated with the between-eye differences in the anterior chamber values of the eye (CP, ACD, LT, ACD + LT). The severity of anisomyopia was significantly correlated with the between-eye differences in VCD.

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“…Myopic anisometropia is generally less amblyogenic than hyperopic anisometropia. Many studies have shown that amblyopia is associated with abnormalities in the development of visual cortex, lateral geniculate nucleus, optic nerve, peripapillary retina nerve fiber layer thickness (RNFLT), central macular thickness (CMT), axial length (AL), and central corneal thickness (CCT) [6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Effect of myopic anisometropia on anterior and posterior ocular segment parameters

et al. 2016

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The purpose of this study is to investigate the differences in anterior and posterior segment parameters of more myopic eyes compared to fellow eyes using spectral domain optical coherence tomography and optical biometer device in patients with myopic anisometropia. This prospective cross-sectional study included 42 myopic anisometropic patients with and without amblyopia, aged between 7 and 40 years old. The refractive error and keratometry values, axial length (AL), central corneal thickness (CCT), peripapillary retinal nerve fiber layer thickness (RNFLT), and central macular thickness (CMT) were evaluated. Eighteen of the patients had myopic anisometropia with amblyopia, and the remaining 24 had myopic anisometropia without amblyopia. There were 23 female and 19 male patients with a mean age as 23.67 ± 10.12 years (range 7-40). The right eyes of the subjects significantly had a higher degree of myopia. There was a significant difference in mean best-corrected visual acuity (0.195 ± 0.234 vs. 0.011 ± 0.025 logMAR, p < 0.001), spherical equivalent refraction (-3.95 ± 1.38 vs. -1.04 ± 0.99 D, p < 0.001), AL (25.06 ± 1.27 vs. 23.99 ± 0.98 mm, p < 0.001), and RNFLT (89.24 ± 12.84 vs. 94.57 ± 10.81 μm, p < 0.001) between the more myopic and fellow eyes in all patients. On the contrary, there was no significant difference in CMT and anterior segment parameters including mean keratometry and CCT in all patients and either group. During the development of the myopic anisometropia, more myopic eyes have significantly more myopic refraction, longer AL and thinner RNFLT compared to the fellow eyes.

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Anisometropic amblyopia: Axial length versus corneal curvature in children with severe refractive imbalance

Cited by 19 publications

References 6 publications

The relationship of axial length to cycloplegic refraction and keratometry in amblyopic eyes of hyperopic children

The relationship of axial length to cycloplegic refraction and keratometry in amblyopic eyes of hyperopic children

The Correlation of Differences in the Ocular Component Values with the Degree of Myopic Anisometropia

Effect of myopic anisometropia on anterior and posterior ocular segment parameters

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