Anisakis allergy in human

Ivanović, Jelena; Baltić, Milan Ž.; Bošković, Marija; Kilibarda, Nataša; Dokmanović, Marija; Marković, Radmila; Janjić, Jelena M.; Baltic, Branislav

doi:10.1016/j.tifs.2016.11.006

Cited by 32 publications

(23 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The spectrum of allergic reactions to Anisakis simplex is wide and includes rhinitis, conjunctivitis, asthma, urticaria/ /angioedema, allergic contact dermatitis, and anaphylactic shock [4,13,14,17].…”

Section: Discussionmentioning

confidence: 99%

“…The condition may be caused through the consumption of infected fish, or from occupational contact. The sectors most affected by Anisakis-related diseases are fishermen/ /women, fishmongers, and chefs: in general, anyone whose work involves catching, cleaning, handling, selling, or preparing contaminated fish [13,18].…”

Section: Discussionmentioning

confidence: 99%

“…However, over the last few years there has been an increase in the number of cases reported in other countries including Italy [8,12] and Spain [6,13].…”

Section: Pathogenesismentioning

confidence: 99%

See 2 more Smart Citations

Occupational disease due to Anisakis simplex in fish handlers

Uña-Gorospe

Herrera-Mozo

Canals³

et al. 2018

International Maritime Health

View full text Add to dashboard Cite

Background: Anisakis is a marine nematode. Its larvae can be found encysted in several species, both in the abdominal cavity and in the adjacent musculature. The most commonly affected commercial species are hake, whiting, cod, and mackerel. The prevalence in fish varies according to the fishing area and the size of the host. Materials and methods: Until now only three species have been confirmed to be involved in human anisakiasis, the most common ones being A. simplex sensu stricto (s.s.) and A. pegreffii, and anecdotally, A. physeteris. Infestation in humans occurs when they eat raw or undercooked parasitized fish or cephalopods (pickled, cold-smoked, salted, semi-preserved, prepared in certain Asian styles like sushi or sashimi, ceviche). Results: The majority of anisakiasis cases have been described by Japanese authors. However, over the last few years there has been an increase in the number of cases reported in other countries including Italy and Spain. It is estimated that its incidence in the European Union is 0.32/100,000, and in the Basque Country (Spain), this parasite is responsible for 10% of anaphylaxis cases and 32% of urticaria cases in adults aged 40-60 years, around 300 cases/year. Anisakis-related disease in the work environment (occupational disease) is less common. Conclusions: We present three cases of the occupational disease in Spain due to a type I hypersensitivity to Anisakis simplex in individuals who handle fish (one fishmonger, one supermarket employee, and one chef).

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Occupational disease due to Anisakis simplex in fish handlers

Uña-Gorospe

Herrera-Mozo

Canals³

et al. 2018

International Maritime Health

View full text Add to dashboard Cite

show abstract

“…Humans are an accidental host of this parasitic nematode. Infection occurs upon consumption of raw or undercooked marine fish and crustaceans contaminated with the third-stage larvae of A. simplex [ 2 ]. Infected dishes of raw fish, such as sushi and sashimi, as well as the consumption of marinated or raw fish in European countries such as Italy and Spain, are significant sources of the infection [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Comparative Proteomics Analysis of Anisakis simplex s.s.—Evaluation of the Response of Invasive Larvae to Ivermectin

Polak

Łopieńska–Biernat

Stryiński

et al. 2020

Genes

View full text Add to dashboard Cite

Ivermectin (IVM), an antiparasitic drug, has a positive effect against Anisakis simplex s.s. infection and has been used for the treatment and prevention of anisakiasis in humans. However, the molecular mechanism of action of IVM on A. simplex s.s. remains unknown. Herein, tandem mass tag (TMT) labeling and extensive liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) analysis were used to identify the effect of IVM on the proteome of A. simplex s.s. in vitro. During the study, 3433 proteins, of which 1247 had at least two protein unique peptides, were identified. Comparative proteomics analysis revealed that 59 proteins were differentially regulated (DRPs) in IVM-treated larvae, of which 14 proteins were upregulated and 38 were downregulated after 12 h of culture, but after 24 h, 12 proteins were upregulated and 22 were downregulated. The transcription level of five randomly selected DRPs was determined by real-time PCR as a supplement to the proteomic data. The functional enrichment analysis showed that most of the DRPs were involved in oxidoreductase activity, immunogenicity, protein degradation, and other biological processes. This study has, for the first time, provided comprehensive proteomics data on A. simplex s.s. response to IVM and might deliver new insight into the molecular mechanism by which IVM acts on invasive larvae of A. simplex s.s.

show abstract

“…Their life cycle involving small crustaceans as an intermediate host, fish and cephalopods as paratenic hosts, and marine mammals as final hosts. Humans become an accidental host of Anisakis larvae usually as a result of consuming infected raw fish or imperfectly cooked fish (Audicana et al 2003;Ivanovic et al 2017). Anisakis infection in human causes an acute gastrointestinal infection with several symptoms such as abdominal pain, diarrhea, nausea and vomiting, a condition known as anisakiasis (Ivanovic et al 2017;Bao et al 2018).…”

Section: Introductionmentioning

confidence: 99%

Presence of Anisakis nematode larvae in Indian mackerel (Rastrelliger spp.) along the Indian Ocean southern coast of East Java, Indonesia

Setyobudi¹,

Rohmah²,

Syarifah³

et al. 2018

Biodiversitas

View full text Add to dashboard Cite

Setyobudi E, Rohmah I, Syarifah RF, Ramatia L, Murwantoko, Sari DWK. 2019. Presence of Anisakis nematode larvae in Indian mackerel (Rastrelliger spp.) along the Indian Ocean southern coast of East Java, Indonesia. Biodiversitas 20: 313-319. In this study, we aimed to determine the prevalence (P), mean intensity (MI) and site of infection of anisakid larvae (Nematoda) in Indian mackerel (Rastrelliger spp.) at the Indian Ocean Southern Coast of East Java. A total of 341 fish were collected from Prigi and Muncar Fish Harbor, East Java during March-April 2018. Each fish specimen was measured in body length and weight, and then dissected for examination of Anisakis larvae in the body cavity, digestive tract, liver, gonad and muscle. The collected larvae were preserved in absolute ethanol for both morphological and molecular identification. The results of this research showed Indian mackerel was susceptible to Anisakis infection (P=17%, MI =6.8 larva/individual fish). Most of the larvae were found in the digestive tract and body cavity, 47.2% and 46.0% respectively. Only a few larvae were found in other internal organs and muscle. Based on morphological identification, these larvae corresponded to Anisakis Type I. Furthermore, in molecular identification using PCR-RFLP, the banding pattern clearly matched with Anisakis typica. The prevalence and mean intensity of Anisakis nematodes on Indian mackerel along the southern coast of East Java seem to be different in each locality and from other adjacent waters as has previously been reported, which may be due to differences in feeding habits and in the distribution of marine mammals as the final host. The results suggest that differences in prevalence and mean intensity of anisakis larvae infection could be developed as a biological indicator of fish stock discrimination. However, clear information regarding food habits of Indian mackerel and migration patterns of the paratenic hosts as well as of marine mammals as final host is needed.

show abstract

Anisakis allergy in human

Cited by 32 publications

References 35 publications

Occupational disease due to Anisakis simplex in fish handlers

Occupational disease due to Anisakis simplex in fish handlers

Comparative Proteomics Analysis of Anisakis simplex s.s.—Evaluation of the Response of Invasive Larvae to Ivermectin

Presence of Anisakis nematode larvae in Indian mackerel (Rastrelliger spp.) along the Indian Ocean southern coast of East Java, Indonesia

Contact Info

Product

Resources

About