Animal models of Takotsubo syndrome: bridging the gap to the human condition
Ermir Zulfaj,
AmirAli Nejat,
Abdulhussain Haamid
et al.
Abstract:Modelling human diseases serves as a crucial tool to unveil underlying mechanisms and pathophysiology. Takotsubo syndrome (TS), an acute form of heart failure resembling myocardial infarction, manifests with reversible regional wall motion abnormalities (RWMA) of the ventricles. Despite its mortality and clinical similarity to myocardial infarction, TS aetiology remains elusive, with stress and catecholamines playing central roles. This review delves into current animal models of TS, aiming to assess their abi… Show more
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