Animal Model Simulation for Training With Split‐Liver Transplants

Fryer, Jonathan P.

doi:10.1002/lt.25418

Cited by 1 publication

(1 citation statement)

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“…Future directions could address the possibility that TVG utilization is due to lack of surgical expertise by development of training seminars, coursework, simulation models, cooperative arrangements, or consolidation of pediatric LT programs and each method to address has been described for other complex surgical procedures previously 25‐27 . The American Society of Transplant Surgeons has recently created and implemented several hands on training programs to increase expertise and application of LD nephrectomy and donation after cardiac death, which are examples of two other technically complex surgical transplant techniques for which centers have demonstrated variable utilization.…”

Section: Discussionmentioning

confidence: 99%

An appraisal of technical variant grafts compared to whole liver grafts in pediatric liver transplant recipients: Multicenter analysis from the SPLIT registry

McElroy

Martin

Feldman

et al. 2022

Pediatric Transplantation

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Background Shortages of liver allografts for children awaiting transplantation have led to high LT waitlist mortality. Prior studies have shown that usage of TVG can reduce waiting time and waitlist mortality, but their use is not universal. We sought to compare patient and graft survival between WLG and TVG and to identify potential associated risk factors in a contemporary pediatric LT cohort. Methods We performed a retrospective analysis of patient survival, graft survival, and biliary and vascular complications for LT recipients <18 years old entered into the Society of Pediatric Liver Transplantation prospective multicenter database. Results Of 1839 LT recipients, 1029 received a WLG and 810 received a TVG from either a LD or a DD. There was no difference in patient survival or graft survival by graft type. Three‐year patient survival and graft survival were 96%, 93%, and 96%, and 95%, 89%, and 92% for TVG‐LD, TVG‐DD, and WLG, respectively. Biliary complications were more frequent in TVG. Hepatic artery thrombosis was more frequent in WLG. Multivariate analysis revealed primary diagnosis was the only significant predictor of patient survival. Predictors for graft survival included time‐dependent development of biliary and vascular complications. Conclusions There were no significant differences in patient and graft survival based on graft types in this North American multi‐center pediatric cohort. Widespread routine use of TVG should be strongly encouraged to decrease mortality on the waitlist for pediatric LT candidates.

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Section: Discussionmentioning

confidence: 99%